Cerebral Cavernous Malformations

About the Disease
Cerebral Cavernous Malformations, also known as cerebral cavernous malformation, is related to cerebral cavernous malformations 2 and cerebral cavernous malformations 3. An important gene associated with Cerebral Cavernous Malformations is KRIT1 (KRIT1 Ankyrin Repeat Containing), and among its related pathways/superpathways are B Cell Receptor Signaling Pathway and MAPK Signaling: Mitogens. The drugs Propranolol and Atorvastatin have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and retina, and related phenotypes are cerebral calcification and intracranial hemorrhage

Common Targets
G207 | EIF4A1 | ROCK1 | ITGB1 | GLI3 | CD14 | Neurotrophic Factor (nonspecified subtype) | KRIT1 | CD200 | PIK3CA | ROCK2 | PDCD10 | IL6R | JAK2 | CCM2 | CD68 | Superoxide dismutase (SOD) (nonspecified subtype) | G6647 | MAP3K3 | NACAD

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