Graves Disease

About the Disease
Graves' Disease, also known as graves disease, is related to graves disease 1 and exophthalmos. An important gene associated with Graves' Disease is GRD2 (Graves Disease, Susceptibility To, 2), and among its related pathways/superpathways are Cytokine Signaling in Immune system and NF-kappaB Signaling. The drugs Methimazole and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include thyroid gland, thyroid and eye, and related phenotypes are endocrine/exocrine gland and immune system

Common Targets
IKZF1 | G3569 | VDR | GPR174 | ROCK1 | FOXO1 | HMGCR | TLR10 | CCR6 | CD247 | GHRL | MTNR1A | HLA-A | ITPR3 | MIF-AS1 | G7124 | LCK | IFNGR1 | G598 | ICAM1 | IL1B | MUC22 | IL10 | CDC42BPG | FSHR | HCP5 | DPP4 | CEP128 | G3605 | PDE10A | PHTF1 | MIR3681HG | MTRR | RAC2 | CD40 | GHRLOS | KALRN | CD44 | LPP | TG | IL3 | IL1RL1 | TNFSF13B | TBX21 | AP4B1 | CTLA4 | MIR7-3HG | MAP3K11 | G4170 | VCAM1 | FOXD3 | SMOC2 | MTNR1B | IL15 | DNMT3B | RARB | ARID5B | JAK2 | MS4A1 | LOC105377877 | COQ8A | IL2 | ZAP70 | FCRL3 | DDAH1 | BACH2 | CYP2R1 | FASLG | JAK1 | MIR182 | ROCK2 | JAK3 | CYP4F22 | IL5 | SLAMF6 | HLX | PTPN22 | G7099 | IL4 | MIR27A | MAGI3 | NRXN1 | SLC25A24 | IKZF3 | MIR7-3 | FCRL2 | HLA-DQB1 | G1786 | IL18RAP | CD3E | MIF | TSHR | PRICKLE1 | HLA-DPB1 | FTO | HLA-C | CD5L | IFIH1 | CYP26B1 | IL13 | CXCL10 | ABCF1 | MIR125A | TLR7 | IRAK1 | HLA-DRB1 | C1QTNF6 | SH2B3 | SCGB3A2 | BCL2L15 | ABO | DCBLD1 | NFKB1 | ATF6 | IL18R1 | LOC101929772 | SLA2 | RND3 | BTG2-DT | RHOA | TSBP1 | FBXL18 | RHOC | FOXP3 | CD3D | HLA-B | ATXN2 | G925 | IL12B | PPARG | LOC105376809 | LOC107985690 | MTHFR | RHOD | ZPBP2 | SELE | CD3 Complex (T Cell Receptor Complex) | PITPNC1 | LOC105372666 | TYK2 | VAV3 | BANK1 | MAGI2 | NR2F6 | G142 | MVB12B | NRXN3 | IL33 | HLA-DQA1 | ESR2 | HCG23 | SOCS3-DT | CD3G | IL2RA | G4851 | CCN1 | THRB | KLF13

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