Disease

Blau Syndrome

About the Disease
Blau Syndrome, also known as arthrocutaneouveal granulomatosis, is related to uveitis and sarcoidosis 1. An important gene associated with Blau Syndrome is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways/superpathways are Innate Immune System and Disease. Affiliated tissues include skin, eye and kidney, and related phenotypes are arthralgia and joint swelling

Common Targets
Serine/Threonine Kinase (nonspecified subtype) | NOD2 | ACVR1 | G114548 | RIPK2

疾病靶点研报
Blau Syndrome

Note: If you'd like to get a target analysis report for Blau Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Blau Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Lissencephaly 2 | Chronic Mucocutaneous Candidiasis | Ulcerative Colitis | Transient Bullous Dermolysis Of The Newborn | Renal-hepatic-pancreatic Dysplasia | Porphyria Cutanea Tarda | Wiedemann-Steiner Syndrome | Carbamoyl Phosphate Synthetase I Deficiency | Triphalangeal Thumb-polysyndactyly Syndrome | Trichothiodystrophy | Congenital Poikiloderma | Allergic Contact Dermatitis | Chediak-Higashi Syndrome | Adenoma, Pleomorphic | Chondrodysplasia Punctata 2, X-linked Dominant | Double Outlet Right Ventricle | Adrenal Insufficiency | Bursitis | Presbyopia | Histoplasmosis | Schizotypal Personality Disorder | Lymphangiomatosis | Cardiomyopathy, Hypertrophic | Hereditary Sensory Neuropathy Type 1 | Arterial Tortuosity Syndrome | Oculocutaneous Albinism Type 4 | Brenner Tumor | Ameloblastoma | Alcoholism | Usher Syndrome Type I | Asperger Syndrome | Scapuloperoneal Myopathy, X-linked Dominant | Cat Eye Syndrome | Bladder Exstrophy | Hypobetalipoproteinemias | Aarskog-Scott Syndrome | Shprintzen-Goldberg Syndrome | Peeling Skin Syndrome, Acral Type | Anxiety Disorders | Evans Syndrome | Acrodermatitis | Hidradenitis Suppurativa | Otitis Media | Von Willebrand Disease | Multiple Sclerosis, Primary Progressive | Chordoma | Short-chain Acyl-CoA Dehydrogenase Deficiency | Epithelial-myoepithelial Carcinoma | Neuromyotonia | Lipid Metabolism Disorders | C3 Glomerulonephritis | Postpartum Depression | Farber Disease | Oligodendroglioma | Conduct Disorder | Skin Carcinoma | Avian Influenza | Myocarditis | Feingold Syndrome | Episodic Ataxia | Hypopituitarism | Metatropic Dysplasia | Pulmonary Sclerosing Hemangioma | Lipoma | Gout | Dent Disease | Parkinson's Disease | Pontocerebellar Hypoplasia Type 2 | Gastroenteritis, Eosinophilic | Granular Corneal Dystrophy | Mabry Syndrome | Spinocerebellar Ataxia Type 12 | Familial Dysautonomia | Exostoses | Antisocial Personality Disorder | Fibrodysplasia Ossificans Progressiva | Niemann-Pick Disease | Chromosome 9q34.3 Deletion Syndrome | Desbuquois Syndrome | Graft-versus-host Disease | Diastrophic Dysplasia | Hypothyroidism | Glycogen Storage Disease Type 0, Muscle | Sensory Neuropathy | Episodic Ataxia Type 1 | Alexander Disease | Exfoliative Dermatitis | Myeloid Leukemia | Parvovirus B19 Infection | Raine Syndrome | Adrenomyeloneuropathy | Prediabetes | Myofibromatosis | Androgen Insensitivity | Pyloric Stenosis, Infantile Hypertrophic | Astrocytoma, Anaplastic | Scleritis | Schwartz-Jampel-Aberfeld Syndrome | Heroin Dependence | Prune Belly Syndrome | Angina Pectoris | Leukoplakia | Leprosy | Spinocerebellar Ataxia Type 8 | Dysplastic Nevus | Multiple Sulfatase Deficiency | Hypoparathyroidism | Chylothorax, Congenital | Vitamin A Deficiency | Myositis | Echinococcosis | Meconium Ileus | Cervical Dystonia | GATA2 Deficiency | Gastric Atrophy | Perivascular Epithelioid Cell Tumor | Lymphoma Lymphoblastic | Esophagitis, Eosinophilic | Mountain Sickness | Joubert Syndrome | Myositis, Focal | Tendinitis | Acromegaly | Dysgerminoma | Proctitis | Sleep Disorder | Dermatofibrosarcoma | Coffin-Lowry Syndrome | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Spinocerebellar Ataxia Type 10 | Cyst | Snyder-Robinson Syndrome | Arthritis | Zollinger-Ellison Syndrome | Vitamin D Deficiency | Glomerulonephritis, Membranous | Ureteropelvic Junction Obstruction | Endometriosis | Panniculitis | Charcot-Marie-Tooth Disease Type 4E | Fahr Disease | Esophageal Carcinoma | Takayasu's Arteritis | Pantothenate Kinase-associated Neurodegeneration | Giant Cell Glioblastoma | Chorioretinitis | Neuromuscular Disorders | Irritable Bowel Syndrome | CHOPS Syndrome | Methylmalonic Acidemia | Esophagitis | Supravalvular Aortic Stenosis | Mesothelioma, Malignant | Optic Nerve Hypoplasia, Bilateral | Chondrosarcoma | Maternally Inherited Diabetes And Deafness | Glycogen Storage Disease | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Alveolar Capillary Dysplasia | Borjeson-Forssman-Lehmann Syndrome | Proximal Symphalangism | Tularemia | Warsaw Breakage Syndrome | Tyrosinemia Type 1 | Metachondromatosis | Cerebral Cavernous Malformations | Arteriovenous Malformations | 3-methylglutaconic Aciduria Type IV | Congenital Generalized Lipodystrophy | Hypertensive Nephropathy | Osteogenesis Imperfecta Type VI | Hyper IgE Syndrome | Anorectal Malformations | Encephalocele | Epilepsy Of Infancy With Migrating Focal Seizures | Neuroma | Micro Syndrome | Leiomyosarcoma | Tracheal Disorders | Retinopathy, Diabetic | Marinesco-Sjogren Syndrome | Juvenile Myelomonocytic Leukemia | Chudley-McCullough Syndrome | Canavan Disease | Saul-Wilson Syndrome | Pterygium | Primary Familial Brain Calcification | Hereditary Hemorrhagic Telangiectasia Type 2 | Sjogren Syndrome | Azoospermia | Chronic Enteropathy Associated With SLCO2A1 Gene | Carcinoma, Merkel Cell | Anorectal Fistula | Epidermolytic Palmoplantar Keratoderma | Chondroma | Learning Disability | Carotid Artery Disease | Hyperlipidemia | Waardenburg Syndrome Type 4 | Globozoospermia | Anthrax | Hashimoto Thyroiditis | Pneumococcal Meningitis | Renal Hypomagnesemia 3 | Fibrillation, Atrial | Esophageal Motility Disorders | Neuromyelitis Optica | Antithrombin III Deficiency | Sleep Apnea, Central | Gilbert Syndrome | Omenn Syndrome | Bulimia Nervosa | McCune-Albright Syndrome | Malignant Fibrous Histiocytoma | Generalized Epilepsy And Paroxysmal Dyskinesia | Kleine-Levin Syndrome | Pityriasis Rubra Pilaris | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Esotropia | Alpha-thalassemia Myelodysplasia Syndrome | Thin Basement Membrane Disease | Lattice Corneal Dystrophy | Pelizaeus-Merzbacher Disease | Chronic Myeloid Leukemia | Pleomorphic Xanthoastrocytoma | Multifocal Motor Neuropathy | Epilepsy | Eiken Syndrome | Congenital Bile Acid Synthesis Defect | Lymphoma, Follicular | Nutrition Disorders | Cranioectodermal Dysplasia | Paracoccidioidomycosis | Hermansky-Pudlak Syndrome | Pseudohermaphroditism | Ganglioglioma | Hepatitis | Basal Ganglia Disease, Biotin-responsive | Wiskott-Aldrich Syndrome | Angiodysplasia | Acute Anterior Uveitis | Spondylosis | Graves Disease | Nephrocalcinosis | Brachydactyly | Congenital Mirror Movements | Episodic Ataxia Type 2 | Mucolipidosis Type III | Trichuriasis | Lymphangioleiomyomatosis | Blepharoconjunctivitis | ACTH-independent Macronodular Adrenal Hyperplasia | Poirier-Bienvenu Neurodevelopmental Syndrome | Bernard-Soulier Syndrome | Heart Block | Congenital Heart Block | Cervicitis | Osteosarcoma | Atopic Dermatitis | Hepatitis, Chronic | Acquired Partial Lipodystrophy | Progressive Familial Intrahepatic Cholestasis Type 2 | Hemangioblastoma | Diarrhea | Tic Disorder | Cerebrotendinous Xanthomatosis | Hypohidrotic Ectodermal Dysplasia | Oculocutaneous Albinism Type 2 | Central Retinal Artery Occlusion | Tuberculosis | Subacute Sclerosing Panencephalitis | Microvillus Inclusion Disease | Isovaleric Acidemia | Nestor-Guillermo Progeria Syndrome | Choriocarcinoma | Neurofibroma | Sotos Syndrome | Pseudohypoparathyroidism Type 1B | Agammaglobulinemia | Gigantism | Encephalopathy, Ethylmalonic | Patent Foramen Ovale | Chanarin-Dorfman Syndrome | Intellectual Disability, Autosomal Dominant 5 | Infantile Liver Failure Syndrome 1 | Carcinoma, Transitional Cell | Scapuloperoneal Spinal Muscular Atrophy | Pierre Robin Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | Carney Triad | Schindler Disease | Charcot-Marie-Tooth Disease Axonal Type 2N | Diabetic Macular Edema | Osteopetrosis | Macrodactyly | Autosomal Recessive Spastic Paraplegia Type 35 | Charcot-Marie-Tooth Disease, Type 2 | Encephalopathy | Mevalonate Kinase Deficiency | Anodontia | Ocular Hypertension | Delayed Sleep Phase Syndrome | Diffuse Intrinsic Pontine Glioma | Early Infantile Epileptic Encephalopathy 28 | Asthma, Exercise-induced | Fucosidosis | Rheumatic Heart Disease | Enlarged Vestibular Aqueduct | Spinocerebellar Ataxia Type 27 | Beare-Stevenson Syndrome | Antley-Bixler Syndrome | Discoid Lupus Erythematosus | Pituitary Disorders | Neurocutaneous Melanocytosis | Cholestasis | Patent Ductus Arteriosus | Mitochondrial Disease | Infectious Diarrhea | Peutz-Jeghers Syndrome | Thalassemia, Beta | Hypermetropia | Dermatitis | Dermatitis Herpetiformis | Hernia, Inguinal | Beckwith-Wiedemann Syndrome | Tibial Muscular Dystrophy | Pseudoexfoliation Syndrome | Schizoaffective Disorder | Leber Hereditary Optic Neuropathy | Sialoadenitis | Kaposiform Hemangioendothelioma | Tumoral Calcinosis | Spinocerebellar Ataxia Type 14 | Neuroleptic Malignant Syndrome | Uveitis | Congenital Myopathy | Molybdenum Cofactor Deficiency | Avellino Corneal Dystrophy | Acute Generalized Exanthematous Pustulosis | Mitochondrial Encephalomyopathy | Interstitial Lung Diseases | Congenital Fiber-type Disproportion Myopathy | Hemochromatosis | Charcot-Marie-Tooth Disease Type 2E | Specific Granule Deficiency | Leukemia | Communication Disorders | Senior-Loken Syndrome | Measles | Spinal Cord Diseases | Carney-Stratakis Syndrome | Rhabdomyosarcoma, Embryonal | Antisynthetase Syndrome | Pneumonia, Mycoplasma | Cystitis, Interstitial | Hyperthermia, Malignant | Osteoarthritis | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Corneal Dystrophy And Perceptive Deafness | Thyroid Hormone Resistance | Aplasia Cutis Congenita | Shwachman-Bodian-Diamond Syndrome | Otitis Externa | Tylosis With Esophageal Cancer | Epidermolysis Bullosa Simplex | MELAS Syndrome | Blepharo-cheilo-odontic Syndrome | Camurati-Engelmann Disease | Periventricular Nodular Heterotopia | IgA Nephropathy | Primary Carnitine Deficiency | Amyotrophic Lateral Sclerosis, Juvenile | Major Depression | Hemangioendothelioma | Hypoplastic Left Heart Syndrome | Bethlem Myopathy | Peroxisomal Disorder | Cardiac Sarcoidosis | GLUT1 Deficiency Syndrome | Tyrosinemia Type 2 | Unverricht-Lundborg Syndrome | IgA Deficiency | Chromosome 16p11.2 Deletion Syndrome | Colitis, Lymphocytic | Charcot-Marie-Tooth Disease, Type 2A | Twin-to-twin Transfusion Syndrome | Acute Motor Axonal Neuropathy | Fibromyalgia | Vogt-Koyanagi-Harada Syndrome | Mucormycosis | Olmsted Syndrome | Bronchiolitis | Menetrier Disease | Sialidosis | Cavitary Optic Disc Anomalies | Periventricular Leukomalacia | Sarcoma, Endometrial Stromal | Hyperferritinemia-cataract Syndrome