Disease

Ollier Disease

About the Disease
Enchondromatosis, Multiple, Ollier Type, also known as enchondromatosis, is related to exostoses, multiple, type i and hereditary multiple osteochondromas, and has symptoms including pain An important gene associated with Enchondromatosis, Multiple, Ollier Type is IDH1 (Isocitrate Dehydrogenase (NADP(+)) 1), and among its related pathways/superpathways are Signal Transduction and Presynaptic function of Kainate receptors. The drug Isotretinoin has been mentioned in the context of this disorder. Affiliated tissues include bone, skin and liver, and related phenotypes are micromelia and visceral angiomatosis

Common Targets
HIF1A | KDM4C | IDH1 | G1029 | IDH2 | VHL

疾病靶点研报
Ollier Disease

Note: If you'd like to get a target analysis report for Ollier Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Ollier Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Rickets | Combined Deficiency Of Factor V And Factor VIII | Diabetic Nephropathy | Mycosis Fungoides | Adenylosuccinate Lyase Deficiency | Dermatitis Herpetiformis | Osteoporosis, Postmenopausal | Sialidosis | Mumps | Scabies | Feingold Syndrome | Dermatitis | Epidermodysplasia Verruciformis | Deafness, Dystonia, And Cerebral Hypomyelination | Macrodactyly | Crisponi Syndrome | Impulse Control Disorder | Early Infantile Epileptic Encephalopathy 28 | Budd-Chiari Syndrome | Erythrokeratodermia Variabilis | Clouston Hidrotic Ectodermal Dysplasia | Juvenile Myelomonocytic Leukemia | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Prader-Willi Syndrome | Methylmalonic Aciduria And Homocystinuria, CblC Type | Anti-NMDA Receptor Encephalitis | TARP Syndrome | Cancer, Prostate | Parkinsonism | Hypogonadism | Trigonocephaly | Farber Disease | Synovitis | Pupil Disorders | Hepatic Steatosis | Acquired Partial Lipodystrophy | Agnathia-Otocephaly Complex | GAPO Syndrome | Sitosterolemia | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Thin Basement Membrane Disease | Seizures-scoliosis-macrocephaly Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Schnitzler Syndrome | Orthostatic Intolerance | Chromosome 9q34.3 Deletion Syndrome | Irritable Bowel Syndrome | Inflammatory Linear Verrucous Epidermal Nevus | Alveolar Capillary Dysplasia | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Unverricht-Lundborg Syndrome | Congenital Disorders Of Glycosylation | Diastrophic Dysplasia | Antisocial Personality Disorder | Acrodysostosis | Seborrheic Dermatitis | Asthma | Klippel-Feil Syndrome | Epithelial-myoepithelial Carcinoma | Carcinoma, Signet Ring Cell | HANAC Syndrome | Gout | Epidermolytic Hyperkeratosis | Hennekam Lymphangiectasia-lymphedema Syndrome | Filariasis | Schindler Disease | Fukuyama Congenital Muscular Dystrophy | Megaloblastic Anemia | Pituitary Stalk Interruption Syndrome | Borjeson-Forssman-Lehmann Syndrome | Palmoplantar Keratoderma | Focal Segmental Glomerulosclerosis | Alcoholism | Gallstones | Hypersensitivity Pneumonitis | Congenital Central Hypoventilation Syndrome | Neurotoxicity | Acrodermatitis Enteropathica | Mitochondrial Disease | Thrombophilia | Presbycusis | Osteosclerosis | Heterotopic Ossification | Encephalopathy, Ethylmalonic | Angioedema | Obesity, Morbid | Polycystic Ovary Syndrome | Tremor | Spinocerebellar Ataxia Type 3 | Omenn Syndrome | Exotropia | Alpers Syndrome | T-cell Leukemia | Allan-Herndon-Dudley Syndrome | Pleurisy | Primary Biliary Cholangitis | Metaphyseal Chondrodysplasia, Schmid Type | Retinal Telangiectasia | Pseudo-pseudohypoparathyroidism | McCune-Albright Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Roberts Syndrome | Basal Cell Nevus Syndrome | Dyslexia | Hodgkin Lymphoma | Bethlem Myopathy | Senior-Loken Syndrome | Osteogenesis Imperfecta Type IV | Giant Axonal Neuropathy | Keratosis, Seborrheic | L-2-Hydroxyglutaric Aciduria | Arthrogryposis | Thrombophlebitis | Agranulocytosis | Pure Autonomic Failure | Bruck Syndrome | Rothmund-Thomson Syndrome | Intermittent Claudication | Myofibromatosis | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Mucolipidosis Type IV | Charcot-Marie-Tooth Disease, Type 1A | Diabetes Type 1 | Pierson Syndrome | Limb Girdle Muscular Dystrophy | Primary Aldosteronism | Sensory Neuropathy | Acromegaly | Endometritis | Dystrophy, Cone-rod | T-cell Lymphoma, Subcutaneous Panniculitis-like | Hepatitis C, Chronic | Acne Vulgaris | Pneumonia, Mycoplasma | Growth Hormone Excess | Keratoacanthoma | Wieacker-Wolff Syndrome | Dysgerminoma | Syndactyly | Liver Diseases | C3 Glomerulopathy | Monilethrix | Trichuriasis | Niemann-Pick Disease | Bursitis | Neurofibroma, Plexiform | Pneumonia, Viral | Vitamin A Deficiency | Joubert Syndrome | Dengue Hemorrhagic Fever | Amyotrophic Lateral Sclerosis | GNE Myopathy | Neuroblastoma | Pseudohypoparathyroidism Type 1A | Nijmegen Breakage Syndrome | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Muscular Dystrophy | Chronic Myeloid Leukemia | Prurigo Nodularis | Ellis-Van Creveld Syndrome | Neonatal Progeroid Syndrome | Meningococcal Infections | Duodenal Atresia | Donnai-Barrow Syndrome | Multiple Sclerosis, Chronic Progressive | Idiopathic Pulmonary Fibrosis | Amish Infantile Epilepsy Syndrome | Waardenburg Syndrome Type 2A | Pachyonychia Congenita | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Familial Hemiplegic Migraine | Urofacial Syndrome | Urticaria | AIDS Dementia Complex | Vogt-Koyanagi-Harada Syndrome | Camptocormia | Noonan Syndrome | Fanconi Syndrome | Basal Ganglia Disease, Biotin-responsive | Ulcerative Colitis | Cantu Syndrome | Leukocyte Adhesion Deficiency Type 1 | Charcot-Marie-Tooth Disease, Type 2A | Episodic Ataxia Type 1 | Kabuki Syndrome | Multiple Sclerosis, Secondary Progressive | Charcot-Marie-Tooth Disease, Type 2C | Salla Disease | Aneurysm, Abdominal Aortic | Pemphigus Foliaceus | Amyloidosis | Bietti Crystalline Dystrophy | Erysipelas | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Leber Hereditary Optic Neuropathy | Pelvic Inflammatory Disease | Marinesco-Sjogren Syndrome | PHARC Syndrome | Multiple Hamartoma Syndrome | Myasthenia | Blepharospasm | Polydactyly | Conn Syndrome | Protein C Deficiency | Azoospermia | Hydrolethalus Syndrome | Menetrier Disease | Coloboma | Basan Syndrome | Cancer, Breast | Glycogen Storage Disease | Microcephalic Primordial Dwarfism | Mitochondrial Cytopathy | Urea Cycle Disorder | Overactive Bladder | Waardenburg Syndrome Type 2E | Multiple Sclerosis, Relapsing-remitting | Hypoproteinemia, Hypercatabolic | Meniere's Disease | Dysfibrinogenemia | Light Chain Amyloidosis | Multicystic Renal Dysplasia | Prune Belly Syndrome | Cancer, Lung | Chromosome 16p11.2 Deletion Syndrome | Skin Papilloma | Cyst | Teratozoospermia | Dominant Optic Atrophy | WAGR Syndrome | Intracerebral Hemorrhage | Hemoglobinopathies | Glioblastoma | Mucolipidosis | Apraxia | Adams-Oliver Syndrome | Malignant Fibrous Histiocytoma | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Myasthenia Gravis | Hepatorenal Syndrome | Pemphigoid | Kindler Syndrome | Poikiloderma With Neutropenia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Vertebrobasilar Insufficiency | Atelosteogenesis Type 2 | Okihiro Syndrome | Congenital Hypofibrinogenemia | Ependymoma | Glutaric Aciduria Type 2 | Methylmalonic Acidemia | Lymphopenia | Schistosomiasis Mansoni | Autosomal Recessive Congenital Ichthyosis | Dementia | Myelofibrosis | Rolandic Epilepsy | Lymphomatoid Granulomatosis | Juvenile Xanthogranuloma | Pelizaeus-Merzbacher Disease | Colitis, Microscopic | Ganglioneuroma | Primary Erythromelalgia | Hypertensive Retinopathy | Diabetes Mellitus, Transient Neonatal | Paget's Disease Of The Breast | Keratitis-ichthyosis-deafness Syndrome | Chronic Kidney Disease | Focal Dermal Hypoplasia | Gerstmann-Straussler-Scheinker Syndrome | Anterior Segment Dysgenesis | Spondylocostal Dysostosis | Ectrodactyly | Cartilage Disorders | Neurodevelopmental Disorders | Retinal Coloboma | Wiedemann-Steiner Syndrome | Pouchitis | Spinocerebellar Ataxia Type 8 | Sleep Disorder | Chondrodysplasia Punctata 1, X-linked Recessive | Osteopetrosis | Sarcoma, Endometrial Stromal | Microcephaly | Cherubism | Hyperparathyroidism, Primary | Heart Septal Defects | Brooke-Spiegler Syndrome | Melanocytic Nevus | Vasculitis | Sporadic Hemiplegic Migraine | Keratosis, Actinic | Familial Digital Arthropathy-brachydactyly | Trichomegaly | Angiomyolipoma | Marfan Syndrome | Sclerocornea | Gestational Trophoblastic Disease | Acne | Hypoparathyroidism | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Sarcoma | Congenital Hereditary Endothelial Dystrophy Type II | Periodontitis | Borderline Personality Disorder | Lipodystrophy | Leishmaniasis, Visceral | Pyruvate Carboxylase Deficiency Disease | Sclerosing Cholangitis | Chorioretinitis | Hyperacusis | Multiple Sclerosis, Primary Progressive | Usher Syndrome | Juvenile Polyposis | Cranial Nerve Disease | Primary Familial Brain Calcification | Schizencephaly | Methemoglobinemia Type IV | Craniolenticulosutural Dysplasia | Gastritis | Aceruloplasminemia | Lattice Corneal Dystrophy | Tinea | Adrenoleukodystrophy, X-linked | Meesmann Corneal Dystrophy | Gingivitis | Adult Polyglucosan Body Disease | Usher Syndrome Type III | Cole-Carpenter Syndrome | Polycythemia Vera | Hairy Cell Leukemia | 3-methylglutaconic Aciduria Type IV | Chronic Leukemia | Mountain Sickness | Glycogen Storage Disease Type 3 | Gastritis, Atrophic | Congenital Dyserythropoietic Anemia Type 1 | Myosin Storage Myopathy | Auriculocondylar Syndrome | Spinocerebellar Ataxia Type 1 | Jawad Syndrome | Hyperlipidemia | Cervical Dystonia | Poretti-Boltshauser Syndrome | Scapuloperoneal Myopathy, X-linked Dominant | Mitochondrial DNA Depletion Syndrome 13 | Esophageal Carcinoma | Congenital Stationary Night Blindness | Hypodontia | Hyperthyroidism | Pneumonia, Bacterial | Pemphigus | Spinocerebellar Ataxia Type 38 | Actinomycetoma | Proctitis | Stevens-Johnson Syndrome | Autosomal Recessive Spastic Paraplegia Type 75 | Fontaine Progeroid Syndrome | Anxiety Disorders | Optic Nerve Diseases | Trichothiodystrophy | Central Retinal Artery Occlusion | Hepatopulmonary Syndrome | Temtamy Preaxial Brachydactyly Syndrome | Osteogenesis Imperfecta Type V | Cerebral Cavernous Malformations | Subacute Sclerosing Panencephalitis | Huntington's Disease | Guillain-Barre Syndrome | Peripheral T-cell Lymphoma | Periventricular Nodular Heterotopia | Blastoma, Pleuropulmonary | Retinitis | Imerslund-Grasbeck Syndrome | Inflammatory Myofibroblastic Tumor | Histiocytic Sarcoma | Nemaline Myopathy 8 | Hyperparathyroidism-jaw Tumor Syndrome | Spinocerebellar Ataxia Type 28 | High Molecular Weight Kininogen Deficiency | Peters-plus Syndrome | Craniopharyngioma | Chronic Granulomatous Disease, X-linked | Fibromuscular Dysplasia | Diamond-Blackfan Anemia | Osteogenesis Imperfecta Type VI | Open-angle Glaucoma | Hyperlipidemia, Familial Combined | Swine Influenza | Eclampsia | Schwannoma | Schistosomiasis | Pontocerebellar Hypoplasia | Autosomal Recessive Spastic Paraplegia Type 54 | Osteomalacia | Hyperekplexia | Plasmacytoma | Spinocerebellar Ataxia Type 27 | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Neurocysticercosis