Limb Girdle Muscular Dystrophy

About the Disease
Limb-Girdle Muscular Dystrophy, also known as lgmd, is related to muscular dystrophy, limb-girdle, autosomal recessive 1 and muscular dystrophy, limb-girdle, autosomal dominant 3. An important gene associated with Limb-Girdle Muscular Dystrophy is CAPN3 (Calpain 3), and among its related pathways/superpathways are Cardiac conduction and DREAM Repression and Dynorphin Expression. The drugs (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium and Lisinopril have been mentioned in the context of this disorder. Affiliated tissues include heart, skeletal muscle and smooth muscle, and related phenotypes are no effect and no effect

Common Targets
SGCD | DYSF | RYR1 | TNPO3 | POMT1 | SGCG | LIMS2 | FLNC | HMGCR | Eukaryotic translation initiation factor 2-alpha kinase (nonspecified subtype) | ANO5 | PLEC | BVES | TOR1AIP1 | DOK7 | POMGNT2 | DNM2 | CAPN3 | FKTN | CHD7 | CPT2 | TRAPPC11 | CRPPA | IGHMBP2 | DNAJB6 | POPDC3 | POMT2 | STIM1 | CLCN1 | PYGM | KBTBD13 | MYOT | ITGA7 | COL6A1 | GAA | DAG1 | TTN | LMNA | LAMA2 | FKRP | VCP | COL6A2 | TCAP | ACTA1 | Angiotensin receptor (AT) (nonspecified subtype) | MAS1 | SGCA | TRIM32 | COL6A3 | MYH7 | SMCHD1 | GMPPB | DMD | CHRNA1 | alpha-Mannosidase (nonspecified subtype) | NEB | DES | SGCB | POMK | PYROXD1 | GNE

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