Congenital Absence Of Vas Deferens

About the Disease
Vas Deferens, Congenital Bilateral Aplasia of, also known as congenital bilateral absence of vas deferens, is related to vas deferens, congenital bilateral aplasia of, x-linked and bronchiectasis with or without elevated sweat chloride 1. An important gene associated with Vas Deferens, Congenital Bilateral Aplasia of is CFTR (CF Transmembrane Conductance Regulator), and among its related pathways/superpathways are CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF) and NO-dependent CFTR activation (normal and CF). The drug Dipeptidyl-Peptidase IV Inhibitors has been mentioned in the context of this disorder. Affiliated tissues include testes, prostate and testis, and related phenotypes are male infertility and obstructive azoospermia

Common Targets
ADGRG2 | CFTR

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