Disease

Sensorineural Hearing Loss

About the Disease
Sensorineural Hearing Loss, also known as sensory hearing loss, is related to deafness, autosomal dominant 1, with or without thrombocytopenia and deafness and myopia, and has symptoms including tinnitus An important gene associated with Sensorineural Hearing Loss is GJB2 (Gap Junction Protein Beta 2). The drugs Lidocaine and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and brain, and related phenotypes are shRNA abundance <= 50% and nervous system

Common Targets
GJB2 | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | AMP-activated protein kinase (AMPK) | MYO7A | COX2 | MYO15A | RNR1 | SERINC2 | SCN10A | gamma-Secretase | TRNS1 | GRXCR1 | TECTA | ATP6V0A4 | HTRA2 | TRNT | HARS2 | TMC1 | KCNQ4 | Interleukin-1 (nonspecified subtype) | COL4A5 | MRPS10 | GJB3 | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | UBXN11 | LMX1A | PADI6 | MINAR2 | IL10RA | MITF | SLC52A2 | ND1 | PRDM2 | PAX3 | CYTB | EYA1 | GRXCR2 | CDK11B | SYNC | SMPD1 | TIMM8A | CENPP | NTRK3 | ILDR1 | COL9A2 | EYA4 | ND2 | GPSM2 | CHD7 | G7124 | SMPX | PCDH15 | IFNLR1 | CRYBG2 | PIPOX | CCDC50 | TAS1R1 | TMTC2 | KIF17 | ADGRV1 | TRNA | BCAP31 | MAF | WFS1 | G4233 | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | TRNE | ATP1A3 | FRMPD3 | ND4 | MCM2 | ZBTB20 | SLC22A4 | LOXHD1 | IL10 | OTOGL | ACTG1 | USH2A | CDC14A | MPZL2 | GJB6 | TRIOBP | ND4L | ATP6 | TRNK | KLHL18 | BCS1L | MYO1C | CCR5 | COCH | OTOF | SOX10 | CLDN14 | PTPN11 | POU3F4 | MIF | STRC | TPRN | CCL2 | MYO3A | GRHL2 | CLDN9 | ND5 | PPP1R1A | SLC26A4 | IL1B | OTOA | TNFRSF1A | PTPRQ | TMPRSS3 | TRNL1 | EHD1 | G114548 | SLITRK6 | CDH23 | IDS | BSND | POU4F3 | COL11A2 | NTRK2 | COX1 | C1orf109 | PRPS1 | NEIL3 | MYO6 | ATP2B2 | CEP78 | TMIE | DIAPH1 | POLD1 | IL12B | TJP2

疾病靶点研报
Sensorineural Hearing Loss

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