X-linked Myotubular Myopathy

About the Disease
Myopathy, Centronuclear, X-Linked, also known as x-linked myotubular myopathy, is related to tooth disease and muscular disease. An important gene associated with Myopathy, Centronuclear, X-Linked is MTM1 (Myotubularin 1), and among its related pathways/superpathways are Metabolism and Glycerophospholipid biosynthesis. The drugs Sodium citrate and Tamoxifen have been mentioned in the context of this disorder. Affiliated tissues include eye, liver and skeletal muscle, and related phenotypes are low apgar score and type 1 fibers relatively smaller than type 2 fibers

Common Targets
VMA21 | MTM1 | RYR1 | SELENON | DNM2 | PIK3C2A | STIM1 | ACTA1 | TPM2 | CCDC78

Note: If you'd like to get a target analysis report for X-linked Myotubular Myopathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of X-linked Myotubular Myopathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Ebstein Anomaly | Mood Disorder | Chylomicron Retention Disease | Cockayne Syndrome | Hyperuricemic Nephropathy, Familial Juvenile | Noonan Syndrome | Chloridorrhea, Congenital | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Coma | Hemolytic Uremic Syndrome | Inborn Errors Of Metabolism | Carotid Artery Disease | Hyperandrogenemia | Osteogenesis Imperfecta Type V | Rheumatic Heart Disease | Spitz Nevus | Stargardt Disease | Kaposi Sarcoma | Pachyonychia Congenita | Congenital Central Hypoventilation Syndrome | Sweet Syndrome | Nephrotic Syndrome Type 1 | Neuroma | Hypertension, Portal | Carcinoma, Signet Ring Cell | Spinocerebellar Ataxia Type 12 | Bullous Pemphigoid | Oculocutaneous Albinism Type 2 | Anorectal Fistula | Schuurs-Hoeijmakers Syndrome | Rett Syndrome | Mycosis Fungoides | Presbyopia | Albinism | Cerebellar Ataxia, Cayman Type | Pityriasis Rubra Pilaris | Woodhouse-Sakati Syndrome | Immunoproliferative Disorders | Low Tension Glaucoma | Generalized Epilepsy With Febrile Seizures Plus | Familial Dysautonomia | Seizures-scoliosis-macrocephaly Syndrome | Paroxysmal Nocturnal Hemoglobinuria | Transcobalamin Deficiency | Hyperinsulinemic Hypoglycemia | Restrictive Dermopathy | Primary Hyperoxaluria Type 1 | Ganglioglioma | Periodontitis | Dysthymia | Osteoglophonic Dysplasia | Tuberculous Meningitis | Preaxial Polydactyly | Focal Cortical Dysplasia Type 2 | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Cartilage Disorders | Enterocolitis, Necrotizing | Klinefelter Syndrome | Nestor-Guillermo Progeria Syndrome | Goldenhar Syndrome | Tularemia | Diabetic Macular Edema | Pearson Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Sclerosteosis 2 | Trichotillomania | Schnyder Crystalline Corneal Dystrophy | Jaundice, Obstructive | Progressive External Ophthalmoplegia | Sick Sinus Syndrome 1 | Alpha-1 Antitrypsin Deficiency | Fontaine Progeroid Syndrome | VACTERL Association | Enlarged Vestibular Aqueduct | Keratosis, Seborrheic | Gastritis | Hyperacusis | Persistent Hyperplastic Primary Vitreous | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Congenital Absence Of Vas Deferens | Farber Disease | Diastrophic Dysplasia | Leprosy | Trichorhinophalangeal Syndrome | Maternally Inherited Diabetes And Deafness | Alpha-mannosidosis | Autosomal Recessive Spastic Paraplegia Type 54 | Allan-Herndon-Dudley Syndrome | Ichthyosis Bullosa Of Siemens | Odonto-onycho-dermal Dysplasia | Galloway-Mowat Syndrome | Macrophagic Myofasciitis | Sleep Apnea | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Chronic Granulomatous Disease, X-linked | Nemaline Myopathy 10 | Tendinitis | Varices | Tyrosinemia Type 2 | Central Retinal Artery Occlusion | Blepharitis | Milk Allergy | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Familial Digital Arthropathy-brachydactyly | Neuroblastoma | Schnitzler Syndrome | Polymyalgia Rheumatica | Nephroblastoma | Myelitis, Transverse | Nevus | Niemann-Pick Disease, Type B | Ghosal Syndrome | Progressive Encephalopathy-optic Atrophy Syndrome | Pantothenate Kinase-associated Neurodegeneration | Tuberculosis | Pleomorphic Xanthoastrocytoma | Pure Red Cell Aplasia | Liver Failure | LEOPARD Syndrome | Acrocallosal Syndrome | Coffin-Siris Syndrome | Lipoma | Hypotension, Orthostatic | Hepatitis | Optic Neuropathy | Scleroderma | Neural Tube Defect | Fetal And Neonatal Alloimmune Thrombocytopenia | Familial Thoracic Aortic Aneurysm | Dengue Shock Syndrome | Sickle Cell Anemia | Chronic Leukemia | 5-oxoprolinase Deficiency | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Glycogen Storage Disease Type 0, Muscle | Plasma Cell Dyscrasia | Zellweger Syndrome | Absence Epilepsy | Cerebellofaciodental Syndrome | Facioscapulohumeral Muscular Dystrophy | Amish Infantile Epilepsy Syndrome | Otopalatodigital Syndrome Type 2 | Acromegaly | Primrose Syndrome | Neurofibroma, Plexiform | Usher Syndrome Type II | Papilloma | Acute Anterior Uveitis | Dominant Optic Atrophy | Alazami Syndrome | Hypodontia | Cabezas Syndrome | Treacher Collins Syndrome | Pregnancy, Ectopic | Temporal Lobe Epilepsy | Nephronophthisis | Cold-induced Sweating Syndrome | Pneumococcal Meningitis | Acral Lentiginous Melanoma | C3 Glomerulonephritis | Neuromyotonia | Alopecia Totalis | Retinal Telangiectasia | Congenital Dyserythropoietic Anemia Type 1 | Blastomycosis | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Agammaglobulinemia | Hypertension, Pulmonary | Orthostatic Intolerance | Paronychia | Spinocerebellar Ataxia Type 6 | Rhizomelic Chondrodysplasia Punctata | Campomelic Dysplasia | Specific Granule Deficiency | Meningeal Melanocytoma | Saethre-Chotzen Syndrome | Autoimmune Polyendocrine Syndrome | Heimler Syndrome | Encephalitis | Kidney Stones | DRESS Syndrome | Metachromatic Leukodystrophy | Hepatitis C, Chronic | Bacterial Meningitis | Persistent Mullerian Duct Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | Parapsoriasis | Seminoma | Autosomal Recessive Congenital Ichthyosis | Osteomyelitis | Mitochondrial DNA Depletion Syndrome 13 | Acrodermatitis | Hydronephrosis | Pulmonary Capillary Hemangiomatosis | Autism Spectrum Disorders | Polycythemia Vera | Thrombophilia | Autism | Metatropic Dysplasia | Antisynthetase Syndrome | Alkaptonuria | Thyrotoxic Periodic Paralysis | DiGeorge Syndrome | Bainbridge-Ropers Syndrome | Spinocerebellar Ataxia Type 15 | Dyslexia | Neuroleptic Malignant Syndrome | Gangliosidosis | Vitamin A Deficiency | Stuttering | Rubinstein-Taybi Syndrome | Vascular Calcification | Cluster Headache | Tenosynovial Giant Cell Tumor | Malonyl-CoA Decarboxylase Deficiency | Acute Tubular Necrosis | Crisponi Syndrome | Congenital Torticollis | Phosphoglycerate Dehydrogenase Deficiency | NDH Syndrome | Hyperferritinemia-cataract Syndrome | Hemophagocytic Lymphohistiocytosis | Heavy Chain Disease | Niemann-Pick Disease, Type C | Blepharo-cheilo-odontic Syndrome | Diabetes Insipidus | Brachial Plexus Neuropathy | Adenylosuccinate Lyase Deficiency | Benign Recurrent Intrahepatic Cholestasis 1 | Erdheim-Chester Disease | Donnai-Barrow Syndrome | KBG Syndrome | Lymphoma Lymphoblastic | Benign Familial Infantile Seizures | Bronchitis, Chronic | Pendred Syndrome | Erythematotelangiectatic Rosacea | Amyloidosis | Amenorrhea | Prune Belly Syndrome | Waardenburg Syndrome Type 4 | Necrotizing Autoimmune Myopathy | Neurofibromatosis Type 1 | Glioblastoma Multiforme | Spinocerebellar Ataxia Type 10 | Succinic Semialdehyde Dehydrogenase Deficiency | Spondylometaphyseal Dysplasia | Congenital Lipoid Adrenal Hyperplasia | Schizencephaly | Congenital Adrenal Hyperplasia 1 | Phenylketonuria II | Mevalonate Kinase Deficiency | Spinocerebellar Ataxia | Chronic Lymphocytic Leukemia | Menkes Disease | Pituitary Disorders | Lattice Corneal Dystrophy | Limb Girdle Muscular Dystrophy | Dermatitis | Vestibular Disease | Carcinoma, Squamous Cell | Motion Sickness | Basan Syndrome | Transient Bullous Dermolysis Of The Newborn | Proteus Syndrome | Familial Glucocorticoid Deficiency | Neurodevelopmental Disorders | Brooke-Spiegler Syndrome | Myocarditis | Nail Disorder, Nonsyndromic Congenital | Peroxisomal Disorder | Eczema | Joubert Syndrome 2 | Dermatofibrosarcoma | X-linked Acrogigantism | Anovulation | Pure Autonomic Failure | Lymphedema-distichiasis Syndrome | Congenital Bilateral Absence Of Vas Deferens | Ectopia Lentis, Isolated, Autosomal Recessive | Neuropathy | Craniopharyngioma | Paroxysmal Kinesigenic Dyskinesia | Chromosome 16p11.2 Deletion Syndrome | Episodic Ataxia Type 2 | Melanoma, Malignant | Gitelman Syndrome | Central Core Disease | Multiple Hamartoma Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Coenzyme Q10 Deficiency | Charcot-Marie-Tooth Disease Type 4D | Sporadic Hemiplegic Migraine | Parvovirus B19 Infection | Creatine Deficiency Syndrome Due To AGAT Deficiency | Saul-Wilson Syndrome | Primary Hyperoxaluria | Waardenburg Syndrome Type 2 | Shprintzen-Goldberg Syndrome | Stroke, Hemorrhagic | Hypocalcemia | Multifocal Motor Neuropathy | Cholestasis, Intrahepatic | Microcephalic Primordial Dwarfism | Papilledema | Asperger Syndrome | Periventricular Nodular Heterotopia | Gerodermia Osteodysplastica | Japanese Encephalitis | Hyperthyroidism | Smith-Lemli-Opitz Syndrome | Citrullinemia | Waardenburg Syndrome Type 2A | Spinocerebellar Ataxia Type 38 | Fibrillation, Atrial | Sclerosing Cholangitis | Juvenile Myoclonic Epilepsy | Wiskott-Aldrich Syndrome | Gastritis, Atrophic | Chronic Thromboembolic Pulmonary Hypertension | Dermatomyositis | Myofibromatosis | Hypertension | Myopathy | Neutrophilia | Birk-Barel Syndrome | Cranioectodermal Dysplasia | Nicolaides-Baraitser Syndrome | Dyggve-Melchior-Clausen Disease | Amelanotic Melanoma | Acute Kidney Injury | Usher Syndrome Type IIC | HUPRA Syndrome | Non-small Cell Lung Cancer | Hepatitis B, Chronic | Mucormycosis | Episodic Ataxia Type 1 | Autosomal Recessive Bestrophinopathy | Gigantism | Cystinosis | Seizures | PHARC Syndrome | Hemimegalencephaly | Tinea Versicolor | Myoclonus | Lymphangiomatosis | Keloid | Hyperbilirubinemia | Chudley-McCullough Syndrome | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Retinopathy Of Prematurity | Hemosiderosis | Monilethrix | Borjeson-Forssman-Lehmann Syndrome | Cataplexy | Rhabdomyosarcoma, Alveolar | Hyperparathyroidism | Takenouchi-Kosaki Syndrome | Waardenburg Syndrome Type 4A | Posterior Polar Cataract | Oculocutaneous Albinism | Costello Syndrome | Prediabetes | Congenital Disorders Of Glycosylation Type II | Chondrodysplasia Punctata 2, X-linked Dominant | Familial Retinal Arterial Macroaneurysm | Hereditary Inclusion Body Myopathy | Spondylosis | Schizoaffective Disorder | Infantile Liver Failure Syndrome 1 | Glutaric Aciduria Type 1 | Osteopathia Striata With Cranial Sclerosis | Ventricular Septal Defect | Progressive Familial Intrahepatic Cholestasis Type 3 | Neuromuscular Disorders | Idiopathic Pulmonary Fibrosis | Spondyloarthritis | Christianson Syndrome | Inflammatory Joint Disease | Pelvic Inflammatory Disease | Congenital Muscular Dystrophy | Pseudohypoparathyroidism Type 1B | Alopecia | Hepatopulmonary Syndrome | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Irritable Bowel Syndrome | Pilomatrix Carcinoma | Combined Deficiency Of Factor V And Factor VIII | Sarcoma, Endometrial Stromal | Von Hippel-Lindau Disease | Allergic Contact Dermatitis | Adenomyosis | Superficial Spreading Melanoma | Postpoliomyelitis Syndrome | Menetrier Disease | Hereditary Pyropoikilocytosis | Congenital Diaphragmatic Hernia | Nanophthalmos | Primary Progressive Aphasia | Mastitis