Myoclonus

About the Disease
Myoclonus is related to myoclonic epilepsy of lafora and progressive myoclonus epilepsy 10. An important gene associated with Myoclonus is AFG3L2 (AFG3 Like Matrix AAA Peptidase Subunit 2), and among its related pathways/superpathways is "Degradation pathway of sphingolipids, including diseases". The drugs Rocuronium and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, kidney and brain, and related phenotypes are no effect and no effect

Common Targets
GRIN1 | SCN8A | ATP13A2 | YEATS2 | PRRT2 | ADCY5 | NHLRC1 | ATP1A3 | SLC6A3 | SGCE | Glutamate Receptor Ionotropic AMPA Receptor | GABA(A) receptor | GBA1 | SLC18A2

Note: If you'd like to get a target analysis report for Myoclonus, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Myoclonus at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

B-cell Prolymphocytic Leukemia | Myosin Storage Myopathy | Nijmegen Breakage Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Craniosynostosis | Chronic Periodontitis | Coenzyme Q10 Deficiency | Pilomatrix Carcinoma | Learning Disability | Sclerosteosis 2 | Pancytopenia | Renal Failure | Donnai-Barrow Syndrome | Dyslexia | Apert Syndrome | Esophageal Motility Disorders | Cranioectodermal Dysplasia | AIDS | Congenital Hereditary Endothelial Dystrophy Type I | Filariasis | Pernicious Anemia | Sensory Neuropathy | Hyperglycemia | Congenital Dyserythropoietic Anemia | Raynaud Phenomenon | Crimean-Congo Hemorrhagic Fever | Hyperostosis | Blastomycosis | Anthrax | Ectrodactyly | Pontocerebellar Hypoplasia | Anti-NMDA Receptor Encephalitis | Angioedema, Hereditary | Skin Carcinoma | Colorectal Adenoma | IMAGe Syndrome | Kleine-Levin Syndrome | Aldosterone Synthase Deficiency | Saethre-Chotzen Syndrome | Lymphoma Lymphoblastic | Leishmaniasis, Cutaneous | Chiari Malformation Type I | Thrombophilia | Spondyloarthritis | Blepharophimosis Syndrome | Hyperinsulinemic Hypoglycemia | Polymyositis | Cysticercosis | Paronychia | Thrombasthenia | Distal Myopathy 2 | Inflammatory Myopathy | Hepatic Adenomatosis | Amebiasis | Homocystinuria | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Mountain Sickness | Pulmonary Alveolar Proteinosis | Skin Fragility-woolly Hair Syndrome | Schuurs-Hoeijmakers Syndrome | Gigantism | Early Infantile Epileptic Encephalopathy 4 | Retinoblastoma | Systemic Lupus Erythematosus | Thyroiditis | Milk Allergy | Hypoplastic Left Heart Syndrome | Holt-Oram Syndrome | Pierpont Syndrome | Myotonia | Epidermal Nevus Syndrome | Combined Deficiency Of Factor V And Factor VIII | Echinococcosis | Portal Vein Thrombosis | Polycystic Kidney, Autosomal Recessive | Cryptococcal Meningitis | Tonsillitis | Seborrheic Dermatitis | Osteopathia Striata With Cranial Sclerosis | Greig Cephalopolysyndactyly Syndrome | Hereditary Sensory And Autonomic Neuropathy | Granular Corneal Dystrophy Type 1 | Multicystic Renal Dysplasia | Polyarteritis Nodosa | Rhizomelic Chondrodysplasia Punctata | LMNA-related Congenital Muscular Dystrophy | Tyrosinemia Type 2 | Exostoses | Hepatitis, Chronic | Larsen Syndrome | Multiple Sclerosis, Chronic Progressive | Familial Pheochromocytoma-paraganglioma | Meningococcal Meningitis | GNE Myopathy | Glaucoma | Keratoconus | Atelosteogenesis Type 1 | Sick Sinus Syndrome | Thalassemia | Chronic Idiopathic Myelofibrosis | Ulcerative Colitis | Antenatal Bartter Syndrome Type 1 | Dent Disease | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Niemann-Pick Disease, Type B | Ichthyosis | Albinism | Ligneous Conjunctivitis | Majeed Syndrome | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Chitayat Syndrome | Alopecia | Hypersensitivity Pneumonitis | Common Variable Immunodeficiency | Sleep Disorder | Obsessive-compulsive Disorder | Familial Retinal Arterial Macroaneurysm | Nephrosclerosis | Light Chain Amyloidosis | Pneumonia, Mycoplasma | Carbohydrate Metabolism Disorders | Cervical Dystonia | Marshall-Smith Syndrome | Mood Disorder | Gastritis, Atrophic | McCune-Albright Syndrome | X-linked Creatine Transporter Deficiency | Ichthyosis, X-linked | Isobutyryl-CoA Dehydrogenase Deficiency | Choroideremia | Withdrawal Syndrome | Azoospermia | Evans Syndrome | Asphyxia Neonatorum | Hepatic Steatosis | Cri-du-chat Syndrome | Waardenburg Syndrome | Localized Scleroderma | Deafness, Dystonia, And Cerebral Hypomyelination | Ovarian Hyperstimulation Syndrome | Barrett Esophagus | Glycogen Storage Disease Type 9 | Spasticity | Congenital Diaphragmatic Hernia | Congestive Heart Failure | Anorexia Nervosa | Lymphoma, Mantle Cell | Tyrosinemia | Myoclonus | Johanson-Blizzard Syndrome | Odonto-onycho-dermal Dysplasia | Infertility, Male | Norrie Disease | Renal-hepatic-pancreatic Dysplasia | Hydrops Fetalis | Hyperthyroidism | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Esophageal Adenocarcinoma | Cholangitis | Charcot-Marie-Tooth Disease Type 2D | Autoimmune Polyendocrine Syndrome | Bacterial Meningitis | Plasmacytoma | GATA2 Deficiency | Cerebellofaciodental Syndrome | Influenza | Myocarditis | Necrotizing Autoimmune Myopathy | Amelogenesis Imperfecta | Intestinal Tuberculosis | Vitreoretinal Degeneration, Snowflake Type | Arts Syndrome | CEDNIK Syndrome | Craniopharyngioma | Neurogenic Bladder | Salla Disease | Primrose Syndrome | Tuberculous Meningitis | Carcinoma, Small Cell | Spinocerebellar Ataxia Type 20 | Retinitis Pigmentosa | Chorea | Antisocial Personality Disorder | Acne Vulgaris | Kindler Syndrome | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Pulmonary Sclerosing Hemangioma | Carotid Artery Disease | Syndactyly | DiGeorge Syndrome | Triphalangeal Thumb-polysyndactyly Syndrome | Reflex Epilepsy | Lipid Storage Diseases | Microphthalmia, Syndromic 7 | Iron Metabolism Disorders | Giant Cell Glioblastoma | Lesch-Nyhan Syndrome | Epicondylitis | Thalassemia, Beta | Usher Syndrome Type III | Otitis Externa | Acute Generalized Exanthematous Pustulosis | Parapsoriasis | Chronic Lymphocytic Leukemia | Fascioliasis | Apparent Mineralocorticoid Excess Syndrome | Schwannoma | Hemolytic Uremic Syndrome | DRESS Syndrome | Von Hippel-Lindau Disease | Eating Disorder | Atopic Dermatitis | Prader-Willi Syndrome | Liver Diseases | Transcobalamin Deficiency | Bursitis | Cystinuria | Lupus Erythematosus | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Hypotrichosis | Osteoarthritis | Pachyonychia Congenita | Myhre Syndrome | Kidney Stones | Focal Facial Dermal Dysplasia | Progressive Familial Intrahepatic Cholestasis Type 3 | Nicolaides-Baraitser Syndrome | Combined Malonic And Methylmalonic Acidemia | Schamberg Disease | Sarcoidosis | Hereditary Xerocytosis | Genitopatellar Syndrome | Neovascular Glaucoma | Primary Hyperoxaluria Type 3 | Takenouchi-Kosaki Syndrome | Neurofibromatosis Type 2 | Primary Aldosteronism | Hypophosphatasia | Waldenstrom Macroglobulinemia | Retinal Dystrophy, Early-onset Severe | Exocrine Pancreatic Insufficiency | Rickets | Blepharoconjunctivitis | Neurofibromatosis-Noonan Syndrome | Dermatofibrosarcoma | Glomerulonephritis, Membranous | Torticollis | Burn-McKeown Syndrome | Angioimmunoblastic T-cell Lymphoma | Waardenburg Syndrome Type 4 | Noonan Syndrome | Knobloch Syndrome | Gyrate Atrophy Of The Choroid And Retina | Scabies | Papilledema | Twin-to-twin Transfusion Syndrome | Congenital Adrenal Hyperplasia 1 | Chylomicron Retention Disease | Rhabdomyosarcoma, Alveolar | Hypertrophy | Anencephaly | Neurodegeneration With Brain Iron Accumulation | Carcinoma, Transitional Cell | Retinal Dystrophy | Charcot-Marie-Tooth Disease Type 2E | Congenital Hereditary Endothelial Dystrophy Type II | Xeroderma Pigmentosum Variant Type | Enlarged Vestibular Aqueduct | Fibrodysplasia Ossificans Progressiva | Greenberg Dysplasia | Calcium Pyrophosphate Deposition Disease | Batten Disease | Nephropathy | Vitelliform Macular Dystrophy | Phenylketonuria II | Cannabis Abuse | Cholangiocarcinoma | KBG Syndrome | Ocular Surface Squamous Neoplasia | Tangier Disease | Intracranial Hypertension | Coffin-Lowry Syndrome | Familial Glucocorticoid Deficiency | Osteoglophonic Dysplasia | Stroke, Ischemic | Frontometaphyseal Dysplasia | Hydronephrosis | Sandhoff Disease | Triple A Syndrome | Metatropic Dysplasia | Pfeiffer Syndrome | Familial Exudative Vitreoretinopathy | Lactose Intolerance | Colitis | Cryptosporidiosis | Chondrodysplasia Punctata 2, X-linked Dominant | Arterial Tortuosity Syndrome | Muscle Wasting | Chanarin-Dorfman Syndrome | Reye Syndrome | Phosphoglycerate Dehydrogenase Deficiency | Rhabdomyosarcoma | Hepatorenal Syndrome | Smith-Lemli-Opitz Syndrome | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Hypopigmentation | Asthma, Exercise-induced | GLUT1 Deficiency Syndrome | Waardenburg Syndrome Type 2 | Congenital Tufting Enteropathy | Pulverulent Zonular Cataract | Adenomyosis | Pompe Disease | Fahr Disease | Waardenburg Syndrome Type 4A | Adenoma, Villous | Blue Rubber Bleb Nevus Syndrome | Amelanotic Melanoma | Dysthymia | Schwannomatosis | Chronic Beryllium Disease | Thin Basement Membrane Disease | Cryopyrin-associated Periodic Syndromes | Alstrom Syndrome | Wagner Disease | Carey-Fineman-Ziter Syndrome | Fetal Akinesia Deformation Sequence | Myelodysplasia | Methemoglobinemia Type IV | Steel Syndrome | Thyroid Dysgenesis | Hartnup Disease | Adenoid Cystic Carcinoma | Anal Fissure | Epithelial-myoepithelial Carcinoma | Ameloblastic Carcinoma | Autoimmune Hemolytic Anemia | Esophagitis | Episodic Ataxia | Acne | Zollinger-Ellison Syndrome | Progressive Myoclonic Epilepsy | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Sporadic Inclusion Body Myositis | Angioedema, Acquired | Lymphangioleiomyomatosis | Aneurysm, Thoracic Aortic | Retinal Detachment | Bronchiectasis | Gout | Colitis, Microscopic | Aspergillosis | Glomerulonephritis, Membranoproliferative | Bartter Syndrome | Cholera | Syncope | Pelvic Inflammatory Disease | Leukoplakia, Oral | Temtamy Preaxial Brachydactyly Syndrome | Juvenile Polyposis | HUPRA Syndrome | Smith-Magenis Syndrome | Myelitis, Transverse | Micropenis | Zygomycosis | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Lennox-Gastaut Syndrome | Xeroderma Pigmentosum | Cancer, Lung | Oculocutaneous Albinism Type 1 | Dystonia-parkinsonism, X-linked | Thanatophoric Dysplasia | Keratosis, Seborrheic | Carcinoma, Merkel Cell | NDH Syndrome | Hypertelorism | Periventricular Nodular Heterotopia | Thrombosis | Paroxysmal Kinesigenic Dyskinesia | Seasonal Mood Disorder | Bone Marrow Necrosis | Discoid Lupus Erythematosus | Bainbridge-Ropers Syndrome | Diabetic Neuropathy | Spermatocele | Malonyl-CoA Decarboxylase Deficiency | Situs Inversus | Celiac Disease | Orotic Aciduria | C3 Glomerulonephritis | Hereditary Coproporphyria | Central Core Disease | Sweet Syndrome | Ehlers-Danlos Syndrome | Omenn Syndrome | Depression | Warsaw Breakage Syndrome | Galactosialidosis | Sick Sinus Syndrome 1 | Retinal Vasculitis