Tangier Disease

About the Disease
Tangier Disease, also known as analphalipoproteinemia, is related to hypoalphalipoproteinemia, primary, 1 and hypoalphalipoproteinemia, primary, 2, and has symptoms including dry skin An important gene associated with Tangier Disease is ABCA1 (ATP Binding Cassette Subfamily A Member 1), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Adenosine and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include lymph node, tonsil and spleen, and related phenotypes are hypertriglyceridemia and hypocholesterolemia

Common Targets
ABCA1 | DPP4 | LIPC | APOA1 | HDAC6

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