Disease

Insulinoma

About the Disease
Insulinoma, also known as islet cell adenoma, is related to islet cell tumor and hypoglycemia. An important gene associated with Insulinoma is MEN1 (Menin 1), and among its related pathways/superpathways are Nervous system development and Glucose / Energy Metabolism. The drugs Bevacizumab and Fluorouracil have been mentioned in the context of this disorder. Affiliated tissues include Pancreas, pancreatic islet and heart, and related phenotypes are hyperhidrosis and tremor

Common Targets
MEG3 | SLC18A2 | G3630 | G2064 | MEN1 | DRD1 | MGMT | GLP1R | ADCY1 | G1956 | SSTR2 | G1950

疾病靶点研报
Insulinoma

Note: If you'd like to get a target analysis report for Insulinoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Insulinoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Whipple's Disease | Micropenis | Tumoral Calcinosis | Hypothyroidism | Distal Spinal Muscular Atrophy | Vaginitis | Pseudohermaphroditism | Esophageal Adenocarcinoma | Bietti Crystalline Dystrophy | Aneurysm, Abdominal Aortic | Specific Granule Deficiency | Cockayne Syndrome | Ghosal Syndrome | Hypertensive Nephropathy | Steel Syndrome | Primary Hyperoxaluria Type 3 | Familial Mediterranean Fever | Arteriovenous Malformations | Temtamy Preaxial Brachydactyly Syndrome | Angelman Syndrome | Superficial Spreading Melanoma | Dementia | Amish Infantile Epilepsy Syndrome | Hepatitis, Autoimmune | Homocystinuria | Dystrophy, Cone-rod | Spinocerebellar Ataxia Type 40 | Withdrawal Syndrome | Bruck Syndrome | Cystinosis | Rhinitis | Poikiloderma With Neutropenia | Enhanced S-cone Syndrome | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Congenital Adrenal Hyperplasia 1 | Infertility, Male | Plasma Cell Dyscrasia | Genitopatellar Syndrome | Multiple Sclerosis, Secondary Progressive | Fuchs Dystrophy | Diabetes Type 1 | Chronic Leukemia | Lewy Body Dementia | Retinopathy Of Prematurity | Sertoli Cell-only Syndrome | Choriocarcinoma | Protein S Deficiency | Shwachman-Bodian-Diamond Syndrome | Duchenne Muscular Dystrophy | Fibromyalgia | Schnitzler Syndrome | T-cell Chronic Lymphocytic Leukemia | Congenital Myasthenic Syndrome | Camurati-Engelmann Disease | Mitochondrial Myopathy | Basan Syndrome | Angioedema, Hereditary | Vitamin K Deficiency | Impetigo | Hypertriglyceridemia | Osteitis | Becker Muscular Dystrophy | Progressive Encephalopathy-optic Atrophy Syndrome | Kashin-Beck Disease | Chronic Lymphocytic Leukemia | Intestinal Tuberculosis | Preaxial Polydactyly | Motor Neuron Diseases | Early Infantile Epileptic Encephalopathy 4 | Cystitis | Erythema Multiforme | Blau Syndrome | Cramp Fasciculation Syndrome | Neuromuscular Disorders | Hepatopulmonary Syndrome | Insulinoma | Infantile Nephropathic Cystinosis | Dysthymia | Hyperammonemia | Lyme Disease | Kallmann Syndrome | Amenorrhea | Larsen Syndrome | Hypercholesterolemia, Familial | Basal Ganglia Disease, Biotin-responsive | Hydronephrosis | Muscular Dystrophy | Galloway-Mowat Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | Barrett Esophagus | Persistent Hyperplastic Primary Vitreous | Urticaria | Thalassemia | Hemolytic Anemia | Chondroma | Metaphyseal Chondrodysplasia, Schmid Type | Evans Syndrome | Sclerocornea | Optic Neuritis | Patent Ductus Arteriosus | Bulimia Nervosa | NDH Syndrome | Raine Syndrome | Aspartylglycosaminuria | Gray Platelet Syndrome | Hyperlipidemia | Dysfibrinogenemia | Hepatic Steatosis | Fetal Akinesia Deformation Sequence | Bronchiolitis | Thyroid Dyshormonogenesis | Peeling Skin Syndrome, Acral Type | Lymphoma | HELLP Syndrome | Sjogren Syndrome | Pyelonephritis | Congenital Bile Acid Synthesis Defect | Gardner Syndrome | Hermansky-Pudlak Syndrome | Celiac Disease | Hypertension | Adenoma, Villous | Primary Torsion Dystonia | Majeed Syndrome | Traboulsi Syndrome | Dengue Shock Syndrome | Succinic Semialdehyde Dehydrogenase Deficiency | Endophthalmitis | Blepharo-cheilo-odontic Syndrome | Eiken Syndrome | Pouchitis | Gitelman Syndrome | Malaria | Splenomegaly | Spinocerebellar Ataxia Type 27 | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Hereditary Sensory And Autonomic Neuropathy | Spondyloepiphyseal Dysplasia Tarda, X-linked | Peyronie's Disease | Pterygium | Alopecia Totalis | Miyoshi Myopathy | Spinocerebellar Ataxia Type 10 | Myoclonus-dystonia Syndrome | Anorectal Malformations | Fundus Albipunctatus | Plasmacytoma | Combined Deficiency Of Factor V And Factor VIII | Lassa Fever | Hypersomnia | Amyloidosis | Methemoglobinemia Type IV | Congenital Generalized Lipodystrophy | Diffuse Palmoplantar Keratoderma | Focal Dermal Hypoplasia | Phosphoglycerate Dehydrogenase Deficiency | Agoraphobia | Acromicric Dysplasia | Overactive Bladder | Cardiac Arrest | Meesmann Corneal Dystrophy | Peutz-Jeghers Syndrome | Myocardial Infarction | Raynaud Phenomenon | Spinocerebellar Ataxia Type 21 | Hereditary Spastic Paraplegia | Potocki-Shaffer Syndrome | Pleurisy | Osteoarthritis | Lentigo | Skin Fragility-woolly Hair Syndrome | Corticobasal Syndrome | Usher Syndrome Type III | Hyperuricemic Nephropathy, Familial Juvenile | Agranulocytosis | Kindler Syndrome | Leiomyoma | Waldenstrom Macroglobulinemia | Chronic Granulomatous Disease, X-linked | Desbuquois Syndrome | Neuroendocrine Cancer | Progressive Familial Intrahepatic Cholestasis Type 3 | Ataxia-ocular Apraxia 2 | Parapsoriasis | Long QT Syndrome Type 2 | Blomstrand Osteochondrodysplasia | Common Cold | Erythropoietic Protoporphyria | Microtia | Hyperostosis | Meconium Ileus | Marinesco-Sjogren Syndrome | Neurofibroma, Plexiform | Juvenile Myoclonic Epilepsy | Hypersensitivity | Carney-Stratakis Syndrome | Adenomatoid Tumor | Sarcoidosis | Multiple Sclerosis, Chronic Progressive | Cerebrotendinous Xanthomatosis | Colitis, Lymphocytic | Rift Valley Fever | Nicotine Dependence | Congenital Dyserythropoietic Anemia Type 4 | Congenital Stationary Night Blindness | Thromboembolism | Asthma | Retinal Degeneration | Periventricular Nodular Heterotopia | Gastrointestinal Disorders | Papilledema | Asperger Syndrome | Periodontitis | Tyrosinemia | Spinocerebellar Ataxia Type 14 | Silver-Russell Syndrome | Creatine Deficiency Syndrome Due To AGAT Deficiency | Proctitis | Niemann-Pick Disease, Type C | Asthma, Exercise-induced | Anorexia Nervosa | Pulverulent Zonular Cataract | Non-small Cell Lung Cancer | Klinefelter Syndrome | Polymyalgia Rheumatica | Hemochromatosis Type 1 | Varices | Chylothorax, Congenital | Glycogen Storage Disease Type 5 | Adenomyosis | Spinocerebellar Ataxia Type 13 | Pulmonary Alveolar Microlithiasis | Erythrokeratodermia Variabilis | Hypertension, Renovascular | Pupil Disorders | Myotonic Disorders | Chromosome 9q34.3 Deletion Syndrome | Kabuki Syndrome 2 | Schizoaffective Disorder | Nicolaides-Baraitser Syndrome | Tracheal Disorders | Diabetes Insipidus, Neurogenic | Epidermolysis Bullosa Simplex, Generalized | Familial Hypertrophic Cardiomyopathy | Membranous Nephropathy | Rolandic Epilepsy | Craniolenticulosutural Dysplasia | Irritable Bowel Syndrome | McKusick Type Metaphyseal Chondrodysplasia | Neuroectodermal Tumors, Primitive | Heart Septal Defects | Lymphoma Lymphoblastic | Niemann-Pick Disease | Premenstrual Syndrome | POEMS Syndrome | Spinocerebellar Ataxia Type 5 | Orotic Aciduria | Myositis | Primrose Syndrome | Pseudohypoparathyroidism Type 1B | Acute Tubular Necrosis | Anal Fissure | Spinocerebellar Ataxia | Renal Hypouricemia | Arthritis | Chorea | Persistent Truncus Arteriosus | Geleophysic Dysplasia | Pfeiffer Syndrome | Gerodermia Osteodysplastica | Paroxysmal Kinesigenic Dyskinesia | Scleroderma, Diffuse | Familial Cerebral Amyloid Angiopathy | Diamond-Blackfan Anemia | Polyneuropathy | Pulmonary Veno-occlusive Disease | Knobloch Syndrome | Carcinoma, Squamous Cell | Focal Segmental Glomerulosclerosis | Sick Sinus Syndrome | Craniopharyngioma | Noonan Syndrome-like Disorder With Loose Anagen Hair | Porencephaly | Papulopustular Rosacea | Liddle Syndrome | Polymyositis | Carpal Tunnel Syndrome | Donnai-Barrow Syndrome | Vitamin A Deficiency | Autism | Hydrolethalus Syndrome | Lateral Meningocele Syndrome | Hemophilia | 3-hydroxy-3-methylglutaric Aciduria | Antisynthetase Syndrome | Cancer, Kidney | Swine Influenza | Jacobsen Syndrome | Relapsing Polychondritis | Osteogenesis Imperfecta Type II | Ischemia | Rash | Parvovirus B19 Infection | Metabolic Diseases | Pulmonary Alveolar Proteinosis | Mucolipidosis Type III | Dementia, Vascular | Osteoglophonic Dysplasia | Polyarteritis Nodosa | Dowling-Degos Disease | Hyperhomocysteinemia | Erythematotelangiectatic Rosacea | Neuromyotonia | Sporadic Hemiplegic Migraine | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Renal Dysplasia | Hemangioendothelioma | Discoid Lupus Erythematosus | Hereditary Xerocytosis | Spinocerebellar Ataxia Type 3 | Spondyloarthritis | Psoriasis | Spinocerebellar Ataxia Type 7 | Fibrillation, Atrial | Olmsted Syndrome | Melanoma | Primary Progressive Aphasia | Brachial Plexus Neuropathy | Multiple Myeloma | X-linked Acrogigantism | Generalized Epilepsy And Paroxysmal Dyskinesia | Schamberg Disease | Shock, Cardiogenic | Lymphoma, Mantle Cell | Hyperinsulinemia | Facioscapulohumeral Muscular Dystrophy Type 1 | Tyrosinemia Type 2 | Tinea | PASLI Disease | Infantile Spasm | Arrhythmogenic Right Ventricular Cardiomyopathy | Heroin Dependence | Acrodysostosis | Brachydactyly | Mucormycosis | Hypodontia | B-cell Prolymphocytic Leukemia | Macrophage Activation Syndrome | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Adrenoleukodystrophy, X-linked | Combined Malonic And Methylmalonic Acidemia | Speech Disorders | Bicuspid Aortic Valve | Myoclonus | Glycogen Storage Disease Type 4 | Duodenal Atresia | Subacute Sclerosing Panencephalitis | Glycogen Storage Disease Type 0 | Congenital Stromal Corneal Dystrophy | Trismus-pseudocamptodactyly Syndrome | Narcolepsy | Mood Disorder | Fibrodysplasia Ossificans Progressiva | Cerebral Amyloid Angiopathy | Spinocerebellar Ataxia Type 17 | Epidermolysis Bullosa Dystrophica | Birt-Hogg-Dube Syndrome | Osteonecrosis Of The Jaw | Myelofibrosis | Goiter | Primary Hyperoxaluria | Episodic Ataxia Type 2 | Bladder Exstrophy | AIDS | Glutaric Aciduria Type 1 | Nasodigitoacoustic Syndrome | Oculocutaneous Albinism Type 1 | Gastritis | Pantothenate Kinase-associated Neurodegeneration | Fibrosarcoma | Hennekam Lymphangiectasia-lymphedema Syndrome | Cancer, Breast | Acrocallosal Syndrome | Anorectal Fistula | PHARC Syndrome | Spondyloperipheral Dysplasia | Blepharophimosis Syndrome | Peroxisomal Disorder | Analgesia | Avian Influenza | Proximal Symphalangism | Amyotrophic Lateral Sclerosis | Epilepsy Of Infancy With Migrating Focal Seizures | Cardiomyopathy, Restrictive | Familial Male-limited Precocious Puberty | Neurofibromatosis-Noonan Syndrome | Cardiomyopathy, Hypertrophic | Biotinidase Deficiency | Cartilage Disorders | Polymicrogyria