Van Der Knaap Disease

About the Disease
Megalencephalic Leukoencephalopathy with Subcortical Cysts, also known as vacuolating megalencephalic leukoencephalopathy with subcortical cysts, is related to megalencephalic leukoencephalopathy with subcortical cysts 2a and megalencephalic leukoencephalopathy with subcortical cysts 1, and has symptoms including ataxia, muscle spasticity and seizures. An important gene associated with Megalencephalic Leukoencephalopathy with Subcortical Cysts is MLC1 (Modulator Of VRAC Current 1), and among its related pathways/superpathways are Sudden infant death syndrome (SIDS) susceptibility pathways and Miscellaneous transport and binding events. Affiliated tissues include brain, cortex and temporal lobe, and related phenotypes are no effect and no effect

Common Targets
MLC1

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