Corneal Ulcer

About the Disease
Corneal Ulcer, also known as ulcerative keratitis, is related to conjunctivitis and pyoderma. An important gene associated with Corneal Ulcer is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Amphotericin B and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include eye, bone marrow and endothelial, and related phenotypes are homeostasis/metabolism and immune system

Common Targets
TLR3 | THBS1 | P2RY2 | FGFR2 | Mucin (nonspecified subtype) | LOX | Matrix Metalloproteinase (MMP) (nonspecified subtype) | TGFB1 | TJP1 | NOD2 | Gap junction Connexin ( (nonspecified subtype) | TGFBR1 | F2 | NTRK1 | Elastase (nonspecified subtype) | LOXL2 | USP10 | GJA1 | Gap Junction Protein (nonspecified subtype) | HYOU1 | ESM1 | Collagenase (nonspecified subtype) | Collagen (nonspecified subtype) | G4233 | PI3

Note: If you'd like to get a target analysis report for Corneal Ulcer, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Corneal Ulcer at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Gardner Syndrome | Craniofacial Dysostosis | Waardenburg Syndrome Type 2A | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Obsessive-compulsive Disorder | Periventricular Leukomalacia | Fetal And Neonatal Alloimmune Thrombocytopenia | Giant Cell Glioblastoma | Lymphoma, Follicular | Proteasome-associated Autoinflammatory Syndrome 2 | Glycogen Storage Disease Type 9 | X-linked Acrogigantism | Cataract | Gastric Atrophy | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Depression | Bone Giant Cell Tumor | Glioblastoma | Congenital Generalized Lipodystrophy | Growth Hormone Excess | Nephropathy | Aromatic L-amino Acid Decarboxylase Deficiency | Rubeosis Iridis | Inflammatory Joint Disease | Botulism | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Carney Triad | Optic Neuropathy, Anterior Ischemic | Craniosynostosis | Brooke-Spiegler Syndrome | Nance-Horan Syndrome | Argininosuccinic Aciduria | Absence Epilepsy | Methylmalonic Acidemia | Fontaine Progeroid Syndrome | Epidermolytic Hyperkeratosis | Vulvovaginitis | Coma | Uremic Pruritus | Diffuse Palmoplantar Keratoderma | Borderline Personality Disorder | Onchocerciasis | Parapsoriasis | Emery-Dreifuss Muscular Dystrophy | Schamberg Disease | Neonatal Progeroid Syndrome | Arteriosclerosis | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Diabetes Type 2 | Unverricht-Lundborg Syndrome | Bicuspid Aortic Valve | Arts Syndrome | Infantile Nephropathic Cystinosis | Thyrotoxic Periodic Paralysis | Paracoccidioidomycosis | Proctitis | Common Cold | Hoyeraal-Hreidarsson Syndrome | Exostoses | Chronic Kidney Disease | Fibronectin Glomerulopathy | Pelizaeus-Merzbacher Disease | Tenosynovial Giant Cell Tumor | Viral Meningitis | Endometriosis | Cutaneous Angiosarcoma | Alcoholism | Mannosidase Deficiency Diseases | Syndactyly | Macrophagic Myofasciitis | Myasthenia | Chylomicron Retention Disease | Waardenburg Syndrome Type 4 | Dysplastic Nevus | Zollinger-Ellison Syndrome | Thanatophoric Dysplasia Type 1 | Congenital Muscular Dystrophy | Scleroderma | Disseminated Superficial Actinic Porokeratosis | ICF Syndrome | Keloid | Ocular Surface Squamous Neoplasia | Osteosclerosis | Amelogenesis Imperfecta | Glaucoma, Congenital | Panuveitis | T-cell Prolymphocytic Leukemia | Uremia | Megalencephaly | Cholestasis, Intrahepatic | Rothmund-Thomson Syndrome | Myelofibrosis | Silicosis | Fibromuscular Dysplasia | Multiple Sclerosis | Blepharospasm | Fahr Disease | Hypothalamic Obesity | Oral Lichen Planus | Diarrhea | Chorioretinitis | Meier-Gorlin Syndrome | Lichen Planus | Hypokalemia | Hereditary Spastic Paraplegia | Nail-Patella Syndrome | Dystonia | Odonto-onycho-dermal Dysplasia | Immunoproliferative Disorders | Pancytopenia | Aarskog-Scott Syndrome | Cold-induced Sweating Syndrome | Renal Hypomagnesemia 3 | Familial Pheochromocytoma-paraganglioma | Loeys-Dietz Syndrome Type 4 | Microtia | Azoospermia | Ornithine Transcarbamylase Deficiency | Pleural Tuberculosis | Infantile Spasm | Hyperthermia, Malignant | Myoclonic Epilepsy With Ragged Red Fibers | Kawasaki Disease | Pituitary Disorders | Myoclonus | Glutaric Aciduria Type 1 | Smith-Lemli-Opitz Syndrome | Alstrom Syndrome | Beare-Stevenson Syndrome | Colitis, Microscopic | Paget's Disease Of The Breast | Blomstrand Osteochondrodysplasia | HIBCH Deficiency | Congenital Nephrotic Syndrome | Aldosteronism | Bronchitis | Hypokalemic Periodic Paralysis | Teratozoospermia | Polycystic Liver | Adenoid Cystic Carcinoma | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Chondrodysplasia Punctata 1, X-linked Recessive | Proximal Symphalangism | Mucolipidosis | Hereditary Sensory Neuropathy Type 1 | Melanoma, Malignant | Alpers Syndrome | Cholecystitis | Central Pain Syndrome | Peeling Skin Syndrome, Acral Type | Disseminated Intravascular Coagulation | Hypotension, Orthostatic | Wieacker-Wolff Syndrome | Hyperparathyroidism, Secondary | Esophagitis, Eosinophilic | Rhinitis | Arthritis, Psoriatic | Periventricular Nodular Heterotopia | Meesmann Corneal Dystrophy | Renal Tubular Dysgenesis | Amblyopia | Periodontitis | Fabry's Disease | Spinocerebellar Ataxia Type 17 | Rickets | Incontinentia Pigmenti | Low Tension Glaucoma | High Molecular Weight Kininogen Deficiency | Transthyretin-related Amyloidosis | Polycystic Ovary Syndrome | Nijmegen Breakage Syndrome | Cholangitis | Intellectual Disability, Autosomal Dominant 5 | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Axenfeld-Rieger Syndrome | Chanarin-Dorfman Syndrome | Toxoplasmosis | Vaginitis | Retinal Vasculitis | Dyggve-Melchior-Clausen Disease | Myopia | Retinitis | Myasthenia Gravis | Analgesia | Hemochromatosis | Hypocalcemia | Primary Familial Brain Calcification | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Epicondylitis | Nail Disorder, Nonsyndromic Congenital | Fowler's Syndrome | Stuttering | Mitochondrial Encephalomyopathy | DNA Ligase IV Deficiency | Glycogen Storage Disease Type 6 | Irritable Bowel Syndrome | Infantile Refsum Disease | Hypersomnia | Fucosidosis | Leprosy | Guillain-Barre Syndrome | Neutropenia | Proopiomelanocortin Deficiency | Charcot-Marie-Tooth Disease, Type 6 | Babesiosis | Gigantism | Alexander Disease | Arthropathy | Angina Pectoris | McCune-Albright Syndrome | Congenital Mirror Movements | Mountain Sickness | Marfan Syndrome | Generalized Epilepsy And Paroxysmal Dyskinesia | Goldenhar Syndrome | Schindler Disease | CHOPS Syndrome | Methemoglobinemia | Epiphyseal Chondrodysplasia, Miura Type | Acrodermatitis | Pernicious Anemia | Learning Disability | Werner's Syndrome | Blue Rubber Bleb Nevus Syndrome | Anemia | Insulinoma | Eosinophilia | Myosin Storage Myopathy | HUPRA Syndrome | Hypodontia | Barakat Syndrome | Premature Ejaculation | Contact Dermatitis | Obesity | Pulmonary Tuberculosis | Short-chain Acyl-CoA Dehydrogenase Deficiency | Cardiospondylocarpofacial Syndrome | Reflex Epilepsy | Ventricular Septal Defect | Gastroschisis | Globozoospermia | Osteoporosis, Postmenopausal | Congenital Dyserythropoietic Anemia Type 1 | Osteitis | Asthma, Nocturnal | Hyperlipidemia | Patent Foramen Ovale | Non-epidermolytic Palmoplantar Keratoderma | Nephrotic Syndrome | Chromosome 16p11.2 Deletion Syndrome | Adrenomyeloneuropathy | Split Hand-foot Malformation | Hypospadias | Smith-Magenis Syndrome | Ischemia | Spinocerebellar Ataxia Type 14 | Carcinoma, Small Cell | Methemoglobinemia Type IV | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Pituitary Stalk Interruption Syndrome | Blastomycosis | Galactosialidosis | Tyrosinemia | Heart Septal Defects | Schuurs-Hoeijmakers Syndrome | Charcot-Marie-Tooth Disease Type 4 | Blepharo-cheilo-odontic Syndrome | Melnick-Needles Syndrome | Majeed Syndrome | Paternal Uniparental Disomy Of Chromosome 14 | Pseudomyxoma Peritonei | Primary Lateral Sclerosis | Nephritis, Interstitial | Mixed Connective Tissue Disease | Metaphyseal Chondrodysplasia, Schmid Type | Peripheral Neuropathy | Campomelic Dysplasia | Epilepsy, Generalized | Motion Sickness | Creutzfeldt-Jakob Disease | Guanidinoacetate Methyltransferase Deficiency | Nasodigitoacoustic Syndrome | Polyomavirus Nephropathy | Spinocerebellar Ataxia Type 15 | Seizures | Sarcoma, Alveolar Soft Part | Loeys-Dietz Syndrome | Epidermolytic Palmoplantar Keratoderma | Hennekam Lymphangiectasia-lymphedema Syndrome | Thyroid Dysgenesis | Pupil Disorders | Osteogenesis Imperfecta | Mitochondrial DNA Depletion Syndrome | ADNP Syndrome | Localized Scleroderma | Metatropic Dysplasia | Esthesioneuroblastoma | Subcortical Band Heterotopia | Branchiootorenal Syndrome | Pure Autonomic Failure | Adenosine Deaminase 2 Deficiency | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Smoldering Myeloma | Jacobsen Syndrome | Retinal Diseases | Trichuriasis | Leiomyoma | 3-methylcrotonyl-CoA Carboxylase Deficiency | Schistosomiasis | Cranioectodermal Dysplasia | Multifocal Motor Neuropathy | Neuroleptic Malignant Syndrome | Hyper IgE Syndrome | Porokeratosis | Metachromatic Leukodystrophy | Pierre Robin Syndrome | Gastritis | Multiple Sclerosis, Secondary Progressive | Pneumococcal Meningitis | Partington Syndrome | Glomerulonephritis, Membranous | Ocular Hypertension | Urticaria | Hypertension, Renovascular | Pneumonia, Viral | Fibrillation, Atrial | Cutaneous Lupus Erythematosus | Cancer, Kidney | Pure Red Cell Aplasia | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Focal Dermal Hypoplasia | Rhabdomyosarcoma, Embryonal | Coronary Artery Disease | Paraganglioma | Cardiomyopathy, Restrictive | Cerebellar Ataxia, Cayman Type | Robinow Syndrome | Myocardial Infarction | Cryoglobulinemia | Scoliosis | Persistent Hyperplastic Primary Vitreous | Congenital Heart Defects | Mesothelioma, Malignant | Angiosarcoma Of The Breast | Necrobiosis Lipoidica | Ghosal Syndrome | Influenza | Familial Digital Arthropathy-brachydactyly | Tay-Sachs Disease | Neurotoxicity | Hyperinsulinemic Hypoglycemia | Infantile Liver Failure Syndrome 1 | Trichorhinophalangeal Syndrome | Situs Inversus | Takayasu's Arteritis | Aicardi-Goutieres Syndrome | Cushing Syndrome | Peters-plus Syndrome | Lissencephaly 2 | Urethritis | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Thyroiditis, Autoimmune | Major Depression | Tularemia | Neurocutaneous Melanocytosis | Papillon-Lefevre Syndrome | Cerebral Amyloid Angiopathy | Hypertensive Retinopathy | Trichomegaly | Autism | Dysequilibrium Syndrome | Martsolf Syndrome | Angiodysplasia | Spinocerebellar Ataxia | Chronic Mucocutaneous Candidiasis | Familial Episodic Pain Syndrome | Scleritis | Brugada Syndrome 1 | Microcephaly | Alzheimer Disease, Late Onset | Fascioliasis | Usher Syndrome Type II | Hyperostosis | Kidney Stones | Epidermolysis Bullosa Simplex | Stromal Corneal Dystrophy | Mosaic Variegated Aneuploidy Syndrome 2 | Rhizomelic Chondrodysplasia Punctata | Congenital Absence Of Vas Deferens | Rheumatoid Arthritis | Esotropia | Hemochromatosis Type 2 | Perivascular Epithelioid Cell Tumor | 3-methylglutaconic Aciduria Type I | Amyloidosis | Huntington's Disease-like 2 | Gastritis, Atrophic | Corneal Dystrophy And Perceptive Deafness | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Hydrops Fetalis