Disease

Congenital Generalized Lipodystrophy

About the Disease
Congenital Generalized Lipodystrophy, also known as berardinelli-seip congenital lipodystrophy, is related to lipodystrophy, congenital generalized, type 4 and lipodystrophy, congenital generalized, type 3, and has symptoms including myalgia An important gene associated with Congenital Generalized Lipodystrophy is BSCL2 (BSCL2 Lipid Droplet Biogenesis Associated, Seipin), and among its related pathways/superpathways are Metabolism and IL-9 Signaling Pathways. The drugs Propoxycaine and Anesthetics, Local have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and heart, and related phenotypes are hepatomegaly and lipodystrophy

Common Targets
SYNE2 | CYP21A2 | CEBPA | AGPAT2 | BSCL2 | CAVIN1 | CAV1 | LEPR | LMNA

疾病靶点研报
Congenital Generalized Lipodystrophy

Note: If you'd like to get a target analysis report for Congenital Generalized Lipodystrophy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Congenital Generalized Lipodystrophy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Fibromyalgia | Cellulitis | Benign Recurrent Intrahepatic Cholestasis 1 | Hypotrichosis | Leber Congenital Amaurosis | Meier-Gorlin Syndrome | Ataxia-ocular Apraxia 2 | Hypospadias | Familial Thoracic Aortic Aneurysm | Gynecomastia | Thrombocytopenia | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Unverricht-Lundborg Syndrome | Amyloidosis | Pregnancy, Ectopic | Hyperparathyroidism | Neuropathy | Menkes Disease | Megalencephaly | Camptocormia | Chromosome 16p11.2 Deletion Syndrome | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Panuveitis | Corneal Ulcer | Meningococcal Meningitis | Lipid Storage Myopathy | Angioedema, Acquired | T-cell Prolymphocytic Leukemia | Fibrodysplasia Ossificans Progressiva | Histoplasmosis | Incontinentia Pigmenti | Porokeratosis | Heart Septal Defects | Cranial Nerve Disease | Congenital Myopathy | Anorectal Malformations | CHOPS Syndrome | D-2-Hydroxyglutaric Aciduria | Primary Aldosteronism | FG Syndrome | Orthostatic Intolerance | T-cell Chronic Lymphocytic Leukemia | VACTERL Association | Fetal Akinesia Deformation Sequence | Optic Neuropathy | Speech Disorders | Split Hand-foot Malformation | Osteomalacia | Botulism | Spondyloarthritis | Spastic Paraplegia Type 7 | Macular Degeneration | Low Tension Glaucoma | Spondylo-ocular Syndrome | Diarrhea | Dementia, Vascular | Beare-Stevenson Syndrome | Thrombosis | Premenstrual Syndrome | Fontaine Progeroid Syndrome | Dysequilibrium Syndrome | Liver Diseases | Pancreatitis, Chronic | Rolandic Epilepsy | Pantothenate Kinase-associated Neurodegeneration | Fibrosarcoma | Allan-Herndon-Dudley Syndrome | Neurofibromatosis | Succinic Semialdehyde Dehydrogenase Deficiency | Lupus Erythematosus | Majeed Syndrome | Arthritis, Psoriatic | Paternal Uniparental Disomy Of Chromosome 14 | Trimethylaminuria | Prediabetes | Bursitis | Left Ventricular Noncompaction | Oculocutaneous Albinism Type 4 | Granuloma Annulare | Hyperthermia, Malignant | Gaucher Disease | Plasma Cell Dyscrasia | Glycogen Storage Disease Type 3 | Homocystinuria | Hepatitis C, Chronic | Alopecia | Carcinoma, Merkel Cell | Cranioectodermal Dysplasia | Congenital Nystagmus | Juvenile Xanthogranuloma | Waldenstrom Macroglobulinemia | Congenital Ichthyosiform Erythroderma | Hereditary Inclusion Body Myopathy | Connective Tissue Disorders | Coloboma | Ureteropelvic Junction Obstruction | Focal Dermal Hypoplasia | Hyperacusis | Hypercholesterolemia | Kohlschutter-Tonz Syndrome | Hypertension | LEOPARD Syndrome | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Mannosidase Deficiency Diseases | Hemimegalencephaly | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Cocaine-Related Disorders | Spinocerebellar Ataxia Type 27 | Angiosarcoma | Pulverulent Zonular Cataract | Sickle Cell Anemia | Amyotrophic Lateral Sclerosis, Juvenile | Familial Hemiplegic Migraine | Tuberculosis | Trichothiodystrophy | Apraxia | Protein C Deficiency | Pontocerebellar Hypoplasia Type 7 | Congenital Mirror Movements | Conjunctivitis, Allergic | Pseudoexfoliation Syndrome | Peeling Skin Syndrome, Acral Type | Hypertension, Portal | Epilepsy | Insulin Resistance | T-cell Lymphoma, Subcutaneous Panniculitis-like | Nephrosclerosis | Cancer, Colon | Pemphigoid | Ellis-Van Creveld Syndrome | GNE Myopathy | Bronchiolitis | Warsaw Breakage Syndrome | Porencephaly | Hyperbilirubinemia, Neonatal | Tumoral Calcinosis | Guillain-Barre Syndrome | Postpartum Depression | Otitis Media | Intracerebral Hemorrhage | Renal Tubular Dysgenesis | Diabetes Type 2 | Acute Anterior Uveitis | Multicystic Renal Dysplasia | Primary Pigmented Nodular Adrenocortical Disease | X-linked Creatine Transporter Deficiency | Primary Carnitine Deficiency | Spinocerebellar Ataxia Type 13 | Autoimmune Hemolytic Anemia | Agammaglobulinemia | Familial Pheochromocytoma-paraganglioma | Epidermal Nevus Syndrome | Pituitary Stalk Interruption Syndrome | Paracoccidioidomycosis | Olmsted Syndrome | Nicotine Addiction | Diamond-Blackfan Anemia | LRBA Deficiency | Disseminated Intravascular Coagulation | Viral Meningitis | Adenocarcinoma | Reye Syndrome | Congenital Disorders Of Glycosylation | Cardiomyopathy, Dilated, 1L | Brugada Syndrome 1 | Vitiligo | Tendinopathy | Varices | Megaloblastic Anemia | 3C Syndrome | Progressive Familial Intrahepatic Cholestasis Type 3 | Fraser Syndrome | Lennox-Gastaut Syndrome | Neuromyelitis Optica | Polydactyly | Gastric Atrophy | Glycogen Storage Disease Type 1 | Traboulsi Syndrome | Congenital Dyserythropoietic Anemia | Spinocerebellar Ataxia Type 7 | Auriculocondylar Syndrome | Senior-Loken Syndrome | Pterygium | Liver Failure, Acute Infantile | Withdrawal Syndrome | Mastitis | Cole-Carpenter Syndrome | HANAC Syndrome | Blau Syndrome | Hypereosinophilic Syndrome | Charcot-Marie-Tooth Disease, Type 2C | Torticollis | Acrocallosal Syndrome | Scleritis | Ependymoma | Neuromyotonia | Von Willebrand Disease | Myelofibrosis | Central Core Disease | Primary Hyperoxaluria | Facioscapulohumeral Muscular Dystrophy | Cholecystitis | Gestational Trophoblastic Disease | Waardenburg Syndrome | Congenital Muscular Dystrophy | Iron Metabolism Disorders | Barakat Syndrome | Ventricular Septal Defect | Smoldering Myeloma | Meningeal Melanocytoma | Binge Eating Disorder | Usher Syndrome | Familial Digital Arthropathy-brachydactyly | Hyperandrogenemia | Fanconi Syndrome | Fukuyama Congenital Muscular Dystrophy | Esophageal Motility Disorders | Progressive Familial Intrahepatic Cholestasis | B-cell Chronic Lymphocytic Leukemia | Saethre-Chotzen Syndrome | Diffuse Mesangial Sclerosis | Vitreoretinal Degeneration, Snowflake Type | Osteochondrosis | Polycythemia | Colitis, Collagenous | Poretti-Boltshauser Syndrome | Lymphoma, B-cell | Adrenal Insufficiency | Sezary Syndrome | Oculodentodigital Dysplasia | Myositis | Delirium | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Familial Male-limited Precocious Puberty | Monilethrix | Leri-Weill Dyschondrosteosis | Persistent Hyperplastic Primary Vitreous | Cystinosis | Mesothelioma, Malignant | VEXAS Syndrome | Distal Myopathy | Cold-induced Sweating Syndrome | Schamberg Disease | Benign Familial Infantile Seizures | Omenn Syndrome | Myoclonus | Charcot-Marie-Tooth Disease Type 2T | Benign Hereditary Chorea | Arthritis, Gouty | Chanarin-Dorfman Syndrome | Mitochondrial Myopathy | AIDS Dementia Complex | Encephalopathy, Glycine | Glomerulonephritis, Membranoproliferative | Woodhouse-Sakati Syndrome | Chromosome 5q Deletion Syndrome | Apparent Mineralocorticoid Excess Syndrome | Antley-Bixler Syndrome | Infantile Spasm | Tonsillitis | Recurrent Respiratory Papillomatosis | Impulse Control Disorder | Neurogenic Bladder | Polyradiculopathy | Hyperbilirubinemia | Pierson Syndrome | Motion Sickness | Retinopathy Of Prematurity | Waardenburg Syndrome Type 2E | Tietze Syndrome | Primrose Syndrome | H Syndrome | Acromesomelic Dysplasia | Temporal Lobe Epilepsy | Hydrops Fetalis | Chordoid Glioma | Pulmonary Vein Stenosis | Pleomorphic Xanthoastrocytoma | Otopalatodigital Syndrome Type 2 | Skin Fragility-woolly Hair Syndrome | Spinocerebellar Ataxia Type 10 | Orotic Aciduria | Van Der Knaap Disease | Polycystic Ovary Syndrome | Alzheimer Disease, Late Onset | Spondyloepiphyseal Dysplasia Tarda, X-linked | Congenital Hereditary Endothelial Dystrophy Type II | Frontometaphyseal Dysplasia | Sialidosis | Mandibuloacral Dysplasia With Type A Lipodystrophy | Lymphoma, Follicular | Non-Langerhans Cell Histiocytosis | Mitochondrial DNA Depletion Syndrome 13 | Bloom Syndrome | Guttate Psoriasis | Borjeson-Forssman-Lehmann Syndrome | Diffuse Intrinsic Pontine Glioma | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Autonomic Neuropathy | Riboflavin Transporter Deficiency Neuronopathy | Infectious Diarrhea | Lipid Storage Diseases | Acral Lentiginous Melanoma | Roberts Syndrome | Arthrogryposis | Angina Pectoris | GM2-gangliosidosis AB Variant | Autoimmune Disease | Pigment Dispersion Syndrome | Salla Disease | Cryptosporidiosis | Neurofibrosarcoma | 3-M Syndrome | Esthesioneuroblastoma | Congenital Diaphragmatic Hernia | Ameloblastoma | Chondroma | Occipital Neuralgia | Neuroblastoma | Mevalonate Kinase Deficiency | Inflammatory Myopathy | Hyperhomocysteinemia | Mountain Sickness | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Mixed Connective Tissue Disease | Diabetes Mellitus, Transient Neonatal | Cerebral Amyloid Angiopathy | Rash | Keloid | Subacute Sclerosing Panencephalitis | Dysmorphophobia | WAGR Syndrome | Pancytopenia | Porphyria | Silicosis | Dysfibrinogenemia | Retinal Vasculitis | DEND Syndrome | Thyrotoxic Periodic Paralysis | Neurodegeneration With Brain Iron Accumulation | Trichomegaly | Myofibromatosis | Pearson Syndrome | Schizotypal Personality Disorder | Demyelinating Diseases | Cerebrotendinous Xanthomatosis | Idiopathic Pulmonary Fibrosis | Hydronephrosis | Schnyder Crystalline Corneal Dystrophy | Meesmann Corneal Dystrophy | Encephalitis | Shprintzen-Goldberg Syndrome | Intracranial Hypertension | Giant Axonal Neuropathy | Leukemia | Leishmaniasis, Visceral | Myosin Storage Myopathy | Chondromyxoid Fibroma | DiGeorge Syndrome | Purpura | Spinocerebellar Ataxia Type 23 | Depression | Pre-eclampsia | Choroiditis | Rift Valley Fever | Learning Disability | Creatine Deficiency Syndrome Due To AGAT Deficiency | Asplenia | Charcot-Marie-Tooth Disease Axonal Type 2N | Blepharitis | Pneumonia, Bacterial | Shock, Cardiogenic | Hypercalciuria | Nance-Horan Syndrome | Personality Disorders | Peutz-Jeghers Syndrome | Trichotillomania | Anovulation | Pyruvate Dehydrogenase Deficiency | Waardenburg Syndrome Type 4A | DNA Ligase IV Deficiency | Renal Dysplasia | Sporadic Inclusion Body Myositis | Epidermolysis Bullosa Simplex | Onchocerciasis | Paraganglioma, Carotid Body | Gray Platelet Syndrome | Chronic Inflammatory Demyelinating Polyneuropathy | Cartilage Disorders | Pycnodysostosis | 3-methylglutaconic Aciduria | Epidermolytic Palmoplantar Keratoderma | Tricho-hepato-enteric Syndrome | Erythropoietic Protoporphyria | Congenital Dyserythropoietic Anemia Type 1 | Familial Mediterranean Fever | Peroxisomal Disorder | Graft-versus-host Disease | Carbohydrate Metabolism Disorders | Deafness, Dystonia, And Cerebral Hypomyelination