Gouty Arthritis

About the Disease
Gout, also known as gouty arthritis, is related to tubulointerstitial kidney disease, autosomal dominant, 1 and phosphoribosylpyrophosphate synthetase superactivity, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Gout is DARS2 (Aspartyl-TRNA Synthetase 2, Mitochondrial), and among its related pathways/superpathways are Toll-Like receptor Signaling Pathways and Drug ADME. The drugs Allopurinol and Febuxostat have been mentioned in the context of this disorder. Affiliated tissues include joint, kidney and skin, and related phenotypes are no effect and no effect

Common Targets
G114548 | CRBN | G3576 | IL1B | IL1RN | G3569 | MIR139 | ADAMTS5 | IL-1 Receptor (nonspecified subtype) | G1432 | SLC22A12 | G7099 | NOD2 | BRD4 | XDH | PPARG | BRPF1 | MEFV | KCNQ1 | GSDMD | G196 | BCAS3 | P2RY14 | SLC2A9 | BRD3 | PPARGC1B | CASP1 | G5743 | P2RX7 | NLRP3 Inflammasome | BRDT

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