Esophageal Adenocarcinoma

About the Disease
Esophagus Adenocarcinoma, also known as esophageal adenocarcinoma, is related to apocrine adenocarcinoma and peptic esophagitis. An important gene associated with Esophagus Adenocarcinoma is HNF1A-AS1 (HNF1A Antisense RNA 1), and among its related pathways/superpathways are Cell differentiation - expanded index and Head and neck squamous cell carcinoma. The drugs FOLFIRINOX and Ramucirumab have been mentioned in the context of this disorder. Affiliated tissues include lymph node, liver and bone marrow, and related phenotypes are gastroesophageal reflux and feeding difficulties in infancy

Common Targets
HEATR3 | AFG3L1P | ZBTB38 | LINC02257 | CCDC26 | DCLRE1B | CDK4 | OMD | FBN1 | LOC105370500 | APOM | KCNN3 | MGST1 | TOP1 | TSPYL5 | LOC105372985 | DNMT3A | AXL | LINC00824 | FGF3 | TAFA5 | G1950 | EMBP1 | ATRX | TYR | BRD4 | RMI2 | ZNF781 | GRIK1 | EXT2 | CDYL2 | MMP3 | CCDC6 | IKZF1 | FAT1 | UGT1A8 | MTHFR | G4851 | MAP2K1 | DIO3 | G2099 | KDM5C | MLPH | PIK3CA | CIC | PGR | LAG3 | MN1 | H4C9 | POLD3 | LOC107986930 | G5743 | G5243 | ERBB3 | NCAM1 | Hedgehog Protein (nonspecified subtype) | NRG1 | NKX2-1 | G3479 | LEF1 | KLHL14 | STXBP4 | G999 | SFMBT2 | FGF4 | G1956 | G4609 | CRKL | RGS17 | DMRT1 | MMP12 | IRS2 | CASC11 | PIK3R1 | BMP3 | CASC8 | FLT1 | PSCA | TRRAP | AKAP6 | ZEB2 | MICA-AS1 | PADI6 | MYH11 | CTNNA2 | ENG | VDR | CDKN2B-AS1 | LRFN2 | SLC22A3 | OGG1 | CTD-2194D22.4 | SLC18A3 | PRDM2 | BTNL2 | ST8SIA1 | TCEAL7 | SLC14A1 | SYK | NOTCH4 | CASP8 | SCARB1 | ST6GAL1 | AP4B1 | SP140 | G3725 | LIN28B | LOC107987449 | HOXD13 | FLACC1 | KCNN4 | G4233 | NTRK3 | LOC105377732 | GSTT1 | BAK1 | PIGU | GRIN2D | PTCH1 | TSC2 | CACNB2 | POU3F1 | SOX2 | LOC107987459 | KDR | ROS1 | RALY | NFKBIA | TSBP1-AS1 | G3480 | EEFSEC | KITLG | TP63 | FAT3 | ACSL3 | TIPARP | TNFRSF19 | COLCA1 | G2064 | TACC3 | FGF6 | CDH17 | PINX1 | XPO1 | NR5A2 | TET2 | LOC105377871 | STK11 | KAT6A | REL | XXYLT1 | PIGR | LOC105369367 | G4170 | SLC39A12 | PHLDB1 | CYP2E1 | PLCE1 | HAGLROS | EMSY | CYP24A1 | SMAD7 | DICER1 | CCHCR1 | ARID5B | PLEKHM1 | IRF4 | NDRG4 | SMARCA4 | UGT2B4 | G3845 | LOC105373874 | ERCC2 | VPS53 | TPR | ULK4 | MSLN | EHBP1 | HIP1 | HACE1 | HYKK | RNF146 | HUNK | TBX3 | SETBP1 | ADH1B | G4193 | MECOM | FERMT2 | PTPDC1 | MMP7 | FLT3 | HELQ | G2033 | RICTOR | PIK3C2B | RAF1 | TMEM178A | CTLA4 | RET | CASC17 | CASC21 | STAT4 | CAV1 | DNAH11 | CBFA2T3 | ELMO1 | PLA2G6 | INHBA | KLC3 | EBF2 | LOC105369705 | SLC4A7 | BACH1 | SP110 | LSP1 | DIRC3 | ZGPAT | MTMR3 | KMT2A | CCAT2 | LGR6 | AXIN1 | OLIG2 | SETD2 | CDKN2A-DT | RB1 | LOC105374265 | EBF1 | MTAP | CCND3 | RTEL1 | EYS | G7015 | PDGFRA | IDH2 | SKAP1 | APC | RHPN2 | CSNK1A1 | PSORS1C1 | FGF10 | PRKDC | TRIM71 | NF1 | SLC22A18 | CHRNA3 | ANKLE1 | MAML2 | ACKR3 | GHR | CDH11 | EMID1 | NSF | DLX2-DT | CFTR | G672 | G7124 | LMTK2 | CCNE1 | IGFBP-AS1 | LOC107984214 | RXRA | VHL | FGF23 | NUAK1 | GNAS | PRNCR1 | GSTM1 | ERBB4 | JAK3 | ZNF671 | ACOXL | AFAP1 | BPTF | DOCK2 | PSORS1C2 | SRP14-DT | LINC01162 | AJAP1 | FGF19 | GC | MPL | ZNF365 | CCDC170 | LOC105378460 | CREBBP | LOC107984363 | HAGLR | ADH7 | MSMB | UGT1A1 | G472 | ZBTB20 | TPPP | CRTC1 | RPL22 | MX2 | CPXM1 | KMT2D | AFAP1-AS1 | PTPN11 | CLPTM1L | LOC105376400 | GJC2 | G3576 | NAA25 | ZNF331 | MYCL | CHST9 | CLTC | TLL1 | ARHGEF5 | HAVCR2 | CTNNB1 | ZNF217 | FAS | ZNF568 | SYNE1 | RUNX1 | EXOC1 | G3082 | POU2AF3 | PER1 | USP44 | GUCY2C | KIT | TIGIT | LOC105372093 | EPHA5 | IRF8 | NOTCH2 | PCAT19 | G7157 | NT5E | GATA3 | IL13 | PBRM1 | SFRP1 | FTO | ARID1A | PALB2 | TBX15 | CHMP4C | FAM118A | G673 | LTBP4 | G596 | G7099 | LRP1B | LOC105376536 | ZNF703 | XRCC1 | YPEL3 | FARP2 | PCAT2 | LOC105372225 | SPART | ARMC2 | CDK10 | AKT3 | SOX10 | CHEK2 | SNCB | RFX6 | CBX7 | HMOX1 | G5133 | ZNF610 | BCL6 | MMP1 | G6774 | FGF14 | ATR | IL23R | TCF7L2 | TGFBR2 | LOC105370003 | HNF1B | RRAD | PRKD2 | LOC105374875 | PIP4K2A | FBXW7 | MSH6 | EPAS1 | LMO1 | CLDN18 | MICA | PTPRC | PDE4D | CDK12 | GRHL1 | BARD1 | PITX1-AS1 | FGFR2 | LIG3 | GNPTAB | KIF1B | CEP72 | G5728 | AURKA | MLLT10 | HNF4G | MRTFA | MAP3K1 | CTXND2 | LOC105370113 | G6714 | LINC02627 | CCND2-AS1 | TNFRSF9 | ATP2B4 | G29126 | TNFRSF13B | BARX1 | ELL | LINC00506 | RAD51B | KDM5A | VTI1A | G595 | MC1R | G1029 | NBAT1 | FANCC | ZNF132 | THADA | TIMP3 | GPX7 | ITPR1 | EMX2 | RTEL1-TNFRSF6B | ATF7IP | MDM4 | PML | CASC15 | NRAS | TNFRSF10B | VAV3 | FADS1 | OPLAH | RIN2 | XBP1 | LOC105372710 | ADH1C | KDM6A | GPBAR1 | MYNN | RGN | TOGARAM1 | ARFRP1 | KLF4 | G4089 | EPHB1 | TRIM8 | G5562 | ITGA6 | PEX14 | SCN10A | CASC16 | SMO | RAD54L | CD3 Complex (T Cell Receptor Complex) | G2475 | GDNF | NCOR1 | ERCC1 | PDLIM5 | MAP2K4 | SH3GL3 | NOTCH3 | CDK6 | COL23A1 | LOC105372815 | LAMA5 | EWSR1 | BAG6 | AFM | BABAM1 | CEBPE | BRCA2 | PAX9 | LOC105370455 | TAB2

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