Meconium Ileus

About the Disease
Meconium Ileus, also known as intestinal obstruction in the newborn due to guanylate cyclase 2c deficiency, is related to duodenal atresia and cystic fibrosis, modifier of, 1, and has symptoms including bowel spasm and gastric distention. An important gene associated with Meconium Ileus is GUCY2C (Guanylate Cyclase 2C). The drugs Sodium citrate and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include colon, liver and small intestine, and related phenotypes are microcolon and meconium ileus

Common Targets
NOS1 | GUCY2C | TGFB1 | MSRA

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