Thyroid Dyshormonogenesis

About the Disease
Familial Thyroid Dyshormonogenesis, also known as thyroid dyshormonogenesis, is related to pendred syndrome and thyroid dyshormonogenesis 5. An important gene associated with Familial Thyroid Dyshormonogenesis is DUOX2 (Dual Oxidase 2), and among its related pathways/superpathways are Regulation of expression of SLITs and ROBOs and Thyroid hormones production and peripheral downstream signaling effects. Affiliated tissues include thyroid, cerebellum and breast, and related phenotypes are elevated circulating thyroid-stimulating hormone concentration and decreased circulating t4 concentration

Common Targets
TG | TSHR

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