Malignant Mesothelioma

About the Disease
Mesothelioma, Malignant, also known as malignant mesothelioma, is related to malignant pleural mesothelioma and peritoneal mesothelioma, and has symptoms including chest pain, dyspnea and fatigue. An important gene associated with Mesothelioma, Malignant is BCL10 (BCL10 Immune Signaling Adaptor), and among its related pathways/superpathways is Cytoskeletal Signaling. The drugs Dexamethasone acetate and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include lung, testis and t cells, and related phenotypes are pleural effusion and cough

Common Targets
HCK | NCOR1 | RNF2 | LINGO2 | SLX4 | GTF2B | PARP3 | FGR | RECQL4 | SMARCC1 | NF2 | FLCN | FOLR2 | CSK | BTK | SMO | ERCC1 | LRRK2 | SLC22A1 | ST14 | MELTF | FGFR2 | GLI2 | LILRB4 | PATZ1 | SMARCA2 | G5133 | KIF7 | KIT | NRAS | CDK6 | ELANE | NAE1 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | RRM1 | CDCA4 | AXL | SUFU | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | CD3 Complex (T Cell Receptor Complex) | CSF1R | G29126 | CSPG4 | Ephrin Receptor (nonspecified subtype) | LAG3 | LCK | CDK4 | LOC102724428 | G7295 | G673 | mTOR complex 1 | RASGRF2 | GLI3 | DDR2 | REV1 | PIK3CB | STK36 | BCR | HHIP | DCK | ARID2 | PAK5 | DNA Topoisomerase II (nonspecified subtype) | FGFR3 | DLC1 | SUPT6H | NFATC2 | G1029 | SLC22A6 | PIK3CD | SLC46A1 | EIF4E | GART | PDGFRB | NR0B2 | G142 | LGALS9 | PDPN | REV3L | TPBG | BRD1 | USP6 | MSLN | FOXM1 | PTCH2 | RBM6 | SLC22A8 | PTCH1 | G2475 | DPP4 | HLA-A | FLT4 | PRF1 | CRTAM | G7157 | IHH | PTK2B | SLC22A2 | SMARCA4 | RAD50 | GSTT1 | NEDD8-activating enzyme E1 | G3480 | DAPK1 | MTHFD1 | G5747 | FLT1 | DICER1 | WWTR1 | NCL | EPHB6 | TNFAIP3 | ERCC2 | mTOR complex 2 | SETD2 | FGFR1 | RARB | Tubulin | FRK | SMARCE1 | RAF1 | BLK | TEK | TGFB2 | FGFR4 | ZIC1 | DDR1 | SIK2 | SAV1 | Transcriptional Enhancer Factor (TEAD) (nonspecified subype) | FOLR1 | MLLT1 | LYN | CTLA4 | PIK3CA | G4233 | PRLR | PBRM1 | FLT3 | Focal Adhesion Kinases (FAK) (nonspecified subtype) | SIK1 | WT1 | PARP2 | G3082 | NF1 | G672 | TYMS | SDK1 | VDAC1 | CMKLR1 | RET | PDGFRA | BRIP1 | TNFRSF8 | GNAS | FYN | G3146 | KMT2D | MGMT | PRDX3 | CREBBP | TOP2A | MTHFR | GSTM1 | VHL | BAP1 | DDX3X | ATR | Histone deacetylase (nonspecified subtype) | DHFR | ARID1A | KDR | VSIR | G2146 | GSTP1 | G1956 | PAX7 | CD19 | THBD | ROBO2 | CYP19A1 | APC | CHEK2 | G3845 | GLI1 | RASSF1 | TGFBR2 | PIK3CG | TNFRSF9 | DCC | ARID3C | G10413 | SBDS | ABL1 | AURKA | G6714 | MLH1 | YES1 | LATS2 | DNA Methyltransferase (DNMT) (nonspecified subtype) | CUBN

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