Disease

Bethlem Myopathy

About the Disease
Bethlem Myopathy 1, also known as bethlem myopathy, is related to collagen vi-related dystrophies and ullrich congenital muscular dystrophy 1. An important gene associated with Bethlem Myopathy 1 is COL6A1 (Collagen Type VI Alpha 1 Chain), and among its related pathways/superpathways are Integrin Pathway and Phospholipase-C Pathway. Affiliated tissues include skeletal muscle, heart and skin, and related phenotypes are emg: myopathic abnormalities and muscular dystrophy

Common Targets
TRPV4 | COL6A1 | COL6A2 | COL6A3 | COL12A1

疾病靶点研报
Bethlem Myopathy

Note: If you'd like to get a target analysis report for Bethlem Myopathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Bethlem Myopathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Cancer, Bladder | Infantile Nephropathic Cystinosis | Mitochondrial Cytopathy | Birk-Barel Syndrome | Congenital Dyserythropoietic Anemia Type 4 | Orotic Aciduria | Hemolytic Uremic Syndrome | Exostoses | Werner's Syndrome | Presbyopia | Maple Syrup Urine Disease | Hairy Cell Leukemia | Li-Fraumeni Syndrome | Arrhythmogenic Right Ventricular Cardiomyopathy | Myhre Syndrome | Neonatal Progeroid Syndrome | Cranial Nerve Disease | Preaxial Polydactyly | Cutaneous Angiosarcoma | Long QT Syndrome Type 2 | Antenatal Bartter Syndrome Type 1 | Spinal Cord Diseases | Epidermodysplasia Verruciformis | Diabetic Neuropathy | Torticollis | Molybdenum Cofactor Deficiency | Cramp Fasciculation Syndrome | Renpenning Syndrome | Avellino Corneal Dystrophy | Lipid Storage Diseases | Hypermethioninemia | Bronchitis | Pycnodysostosis | Bainbridge-Ropers Syndrome | Netherton Syndrome | Giant Cell Arteritis | Congenital Absence Of Vas Deferens | Delirium | Erysipelas | Spinocerebellar Ataxia Type 2 | Congenital Hemolytic Anemia | Liver Diseases | Cryptorchidism | Impetigo | Neuronal Ceroid Lipofuscinosis | Danon Disease | Neutropenia | Mast Cell Leukemia | Avian Influenza | Poirier-Bienvenu Neurodevelopmental Syndrome | Thromboembolism | Parkinson's Disease | Hypercholesterolemia | Asthma | Adenoid Cystic Carcinoma | Nemaline Myopathy 8 | Dyslipidemia | Progressive Familial Intrahepatic Cholestasis | Chronic Thromboembolic Pulmonary Hypertension | Sclerocornea | T-cell Chronic Lymphocytic Leukemia | Nephronophthisis | Pernicious Anemia | Cysticercosis | Eiken Syndrome | Keratitis | Benign Recurrent Intrahepatic Cholestasis 1 | Rhabdomyosarcoma, Alveolar | Sick Sinus Syndrome 1 | Primary Carnitine Deficiency | Language Disorders | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Progressive Familial Intrahepatic Cholestasis Type 1 | Delayed Sleep Phase Syndrome | Shwachman-Bodian-Diamond Syndrome | Angioedema | Methemoglobinemia Type IV | Antisocial Personality Disorder | Cohen Syndrome | Melanoma | Mitochondrial Disease | Ebstein Anomaly | Panniculitis | Brachydactyly | Aplasia Cutis Congenita | Myocarditis | Riboflavin Transporter Deficiency Neuronopathy | Neurogenic Bladder | Hyperhomocysteinemia | Gangliosidosis, GM1 | Obesity, Morbid | Hepatitis B, Chronic | Diabetic Nephropathy | Vertigo | Niemann-Pick Disease | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Analgesia | Enhanced S-cone Syndrome | Neuromyotonia | Cholera | Dystonia | Scleroderma, Diffuse | Schizotypal Personality Disorder | Pemphigus Vulgaris | Bone Marrow Necrosis | Glanzmann Thrombasthenia | Chromosome 17q21.31 Deletion Syndrome | Progressive Encephalopathy-optic Atrophy Syndrome | Prolymphocytic Leukemia | Sjogren Syndrome | Fukuyama Congenital Muscular Dystrophy | Hypertensive Retinopathy | Non-epidermolytic Palmoplantar Keratoderma | Metatropic Dysplasia | Alcoholism | Acromesomelic Dysplasia | Esophageal Motility Disorders | Left Ventricular Noncompaction | Metabolic Syndrome | Schwannomatosis | Cannabis Abuse | Waardenburg Syndrome | Spinocerebellar Ataxia Type 12 | Hereditary Folate Malabsorption | Congenital Heart Block | Periventricular Nodular Heterotopia | Leiomyosarcoma | Papillorenal Syndrome | Bullous Pemphigoid | Progressive Myoclonic Epilepsy | Mandibuloacral Dysplasia With Type A Lipodystrophy | Diffuse Mesangial Sclerosis | Papulopustular Rosacea | Pure Autonomic Failure | Pulmonary Stenosis | Mitochondrial DNA Depletion Syndrome | Retinal Vasculitis | Optic Nerve Hypoplasia, Bilateral | Hyper IgE Syndrome | Glycogen Storage Disease Type 0 | Pyelonephritis | Fetal Alcohol Syndrome | Liebenberg Syndrome | Exfoliative Dermatitis | Fibrodysplasia Ossificans Progressiva | Multiple Sclerosis, Primary Progressive | Dominant Optic Atrophy | Leprosy | Spinocerebellar Ataxia Type 13 | Dubin-Johnson Syndrome | Acute Leukemia | Polycythemia Vera | Esophagitis, Eosinophilic | Lipid Metabolism Disorders | Plasmacytoma | Fontaine Progeroid Syndrome | Myoclonus | Giant Axonal Neuropathy | Carpal Tunnel Syndrome | GAPO Syndrome | Costello Syndrome | Neurofibrosarcoma | Amyloidosis | Amyotrophic Lateral Sclerosis | Eosinophilia | Meleda Disease | Coronary Restenosis | Esophageal Adenocarcinoma | Inflammatory Bowel Disease | Keratosis | Autonomic Nervous System Disorders | Coffin-Siris Syndrome | Trigonocephaly | Hypermetropia | Hepatic Steatosis | Seborrheic Dermatitis | Progressive Familial Intrahepatic Cholestasis Type 2 | Low Tension Glaucoma | Hepatitis | Prostatitis | Sezary Syndrome | Erythropoietic Protoporphyria | Nephritis, Interstitial | Acute Generalized Exanthematous Pustulosis | Endometriosis | Congestive Heart Failure | Primary Hyperoxaluria Type 1 | Vasculitis | Tyrosinemia Type 2 | Spinocerebellar Ataxia Type 27 | Spinocerebellar Ataxia Type 8 | 3-methylglutaconic Aciduria | Persistent Fetal Circulation | Smith-Lemli-Opitz Syndrome | Pseudoexfoliation Syndrome | Pseudohermaphroditism | VACTERL Association | Desbuquois Syndrome | Adams-Oliver Syndrome | Multiple Hamartoma Syndrome | Pyruvate Kinase Deficiency | Recurrent Respiratory Papillomatosis | Glioblastoma | Rubeosis Iridis | Autosomal Recessive Bestrophinopathy | Acute Lung Injury | Spinocerebellar Ataxia Type 40 | Sarcomatoid Carcinoma Of The Lung | Raine Syndrome | Orthostatic Intolerance | Chronic Mucocutaneous Candidiasis | X-linked Creatine Transporter Deficiency | Angioedema, Hereditary | Non-bullous Congenital Ichthyosiform Erythroderma | Rotor Syndrome | Ileitis | Cystinosis | Hepatopulmonary Syndrome | POEMS Syndrome | Anencephaly | Premenstrual Syndrome | Diabetes Mellitus, Transient Neonatal | Roberts Syndrome | Zollinger-Ellison Syndrome | Photosensitivity | Sturge-Weber Syndrome | Osteogenesis Imperfecta Type I | Congenital Heart Defects | Conjunctivitis | Vestibular Disease | Sarcoma, Alveolar Soft Part | Insulinoma | Polycythemia | Frank-ter Haar Syndrome | Emery-Dreifuss Muscular Dystrophy | Vitelliform Macular Dystrophy | Sitosterolemia | IMAGe Syndrome | Pitt-Hopkins Syndrome | Juvenile Polyposis | Zimmermann-Laband Syndrome | Prolactinoma | Spitzoid Melanoma | Apraxia | Spondylocarpotarsal Synostosis Syndrome | Non-small Cell Lung Cancer | Pyruvate Carboxylase Deficiency Disease | Retinitis | Antithrombin III Deficiency | Tendinopathy | High Molecular Weight Kininogen Deficiency | Moyamoya Disease | Barrett Esophagus | Walker-Warburg Syndrome | Communication Disorders | Scabies | Situs Inversus | Corneal Dystrophy And Perceptive Deafness | Osteonecrosis | Congenital Nephrotic Syndrome | Systemic Lupus Erythematosus | Epilepsy, Generalized | Congenital Poikiloderma | Actinomycetoma | Acanthosis Nigricans | IgA Deficiency | Branchiootorenal Syndrome | Globozoospermia | Hypervalinemia | Ameloblastoma | Charcot-Marie-Tooth Disease Type 4B1 | Gardner Syndrome | Autism | Porphyria, Variegate | Thyroid Dyshormonogenesis | Congenital Afibrinogenemia | Insulin Resistance | Borjeson-Forssman-Lehmann Syndrome | Diffuse Intrinsic Pontine Glioma | Familial Retinal Arterial Macroaneurysm | Erythema Multiforme | Hereditary Coproporphyria | Episodic Ataxia Type 2 | Intestinal Hypomagnesemia 1 | Osteosarcoma | Anuria | Hereditary Sensory Neuropathy Type 1 | Arthritis | GLUT1 Deficiency Syndrome | Hyperphenylalaninemia | Prolidase Deficiency | Agranulocytosis | Conduct Disorder | Kernicterus | CDKL5 Deficiency Disorder | Congenital Dyserythropoietic Anemia | GNE Myopathy | Iron Deficiency Anemia | Ganglioneuroma | Measles | Angina Pectoris | Liddle Syndrome | Melnick-Needles Syndrome | Transient Bullous Dermolysis Of The Newborn | Cardiospondylocarpofacial Syndrome | Rhinitis | Alpha-thalassemia Myelodysplasia Syndrome | Wieacker-Wolff Syndrome | Early Infantile Epileptic Encephalopathy 13 | Rett Syndrome | Infertility | Hypoplastic Left Heart Syndrome | Myopathy | Tay-Sachs Disease | Hypopituitarism | Thyrotoxic Periodic Paralysis | Exocrine Pancreatic Insufficiency | Auriculocondylar Syndrome | Renal Hypomagnesemia 3 | Kleine-Levin Syndrome | Angiosarcoma Of The Breast | Multifocal Motor Neuropathy | Paroxysmal Nocturnal Hemoglobinuria | Rosacea | Syndactyly | Glomerulonephritis, Membranous | Cantu Syndrome | Charcot-Marie-Tooth Disease Type 2D | Dysmorphophobia | Asperger Syndrome | Peritonitis | Hypersensitivity | Enterocolitis, Necrotizing | Gliosarcoma | Episodic Ataxia | Tangier Disease | Glycogen Storage Disease Type 0, Muscle | Mitochondrial DNA Depletion Syndrome 13 | Diabetic Encephalopathy | Metachondromatosis | Uveitis | Hypodontia | Skin Carcinoma | Congenital Lipoid Adrenal Hyperplasia | Sclerosteosis 2 | Lassa Fever | Idiopathic Multicentric Castleman Disease | Cholesteryl Ester Storage Disease | Myelodysplasia | Glomerulonephritis | Polymyositis | Paracoccidioidomycosis | Otitis Media | Autosomal Recessive Spastic Paraplegia Type 75 | Nijmegen Breakage Syndrome | Desmosterolosis | Hypotrichosis | Constipation | Spinocerebellar Ataxia Type 15 | Myelofibrosis | Early Infantile Epileptic Encephalopathy 1 | Progressive Osseous Heteroplasia | Light Chain Amyloidosis | Hemophagocytic Lymphohistiocytosis | Teratozoospermia | Beckwith-Wiedemann Syndrome | Inflammatory Linear Verrucous Epidermal Nevus | X-linked Charcot-Marie-Tooth Disease | Oculopharyngeal Muscular Dystrophy | Clouston Hidrotic Ectodermal Dysplasia | Corneal Neovascularization | Dysplastic Nevus | Spondylosis | Hypobetalipoproteinemias | Hemimegalencephaly | Binge Eating Disorder | Leukoplakia | Vitamin D Deficiency | Pseudo-pseudohypoparathyroidism | Pleurisy | Scleritis | Pierre Robin Syndrome | Hypopigmentation | Ollier Disease | Anal Fissure | Waardenburg Syndrome Type 2E | Pyoderma Gangrenosum | Diabetes Insipidus, Nephrogenic | Turner's Syndrome | Astrocytoma, Anaplastic | Bartsocas-Papas Syndrome | Tibial Muscular Dystrophy | Coloboma | Familial Glucocorticoid Deficiency | Thyroiditis, Autoimmune | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Granular Corneal Dystrophy Type 1 | Encephalopathy, Glycine | Familial Male-limited Precocious Puberty | Yellow Fever