Disease

Histiocytosis

About the Disease
Histiocytosis, also known as hand schuller christian disease, is related to histiocytosis-lymphadenopathy plus syndrome and langerhans cell sarcoma. An important gene associated with Histiocytosis is SLC29A3 (Solute Carrier Family 29 Member 3), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Prednisone and glucocorticoids have been mentioned in the context of this disorder. Affiliated tissues include lung, bone and liver, and related phenotypes are no effect and no effect

Common Targets
MAP2K1 | ALDH2 | G3845 | UNC13D | G7124 | ADH1B | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | SLC29A3 | PRF1 | CBL | G673 | CRBN | PARP2 | Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) (nonspecified subtype) | NRAS | PDGFRB | LPIN1 | PARP3 | G142

疾病靶点研报
Histiocytosis

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