Glycogen Storage Disease Type 5

About the Disease
Glycogen Storage Disease V, also known as myophosphorylase deficiency, is related to metabolic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration and myoglobinuria, recurrent. An important gene associated with Glycogen Storage Disease V is PYGM (Glycogen Phosphorylase, Muscle Associated), and among its related pathways/superpathways are Metabolism and Glycosaminoglycan metabolism. The drugs Valproic acid and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include kidney, skeletal muscle and brain, and related phenotypes are highly elevated creatine kinase and glycogen accumulation in muscle fiber lysosomes

Common Targets
AMPD1 | HDAC1 | PPARD | PYGM | APEH

Note: If you'd like to get a target analysis report for Glycogen Storage Disease Type 5, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Glycogen Storage Disease Type 5 at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Peeling Skin Syndrome, Acral Type | Phenylketonuria | Hepatopulmonary Syndrome | Dengue Shock Syndrome | Pancytopenia | Usher Syndrome Type IIC | Mohr-Tranebjaerg Syndrome | Babesiosis | Transthyretin-related Amyloidosis | Bloom Syndrome | Spinocerebellar Ataxia Type 6 | Malonyl-CoA Decarboxylase Deficiency | Schistosomiasis | Erythropoietic Protoporphyria | Multisystemic Smooth Muscle Dysfunction Syndrome | Lung Diseases | Noonan Syndrome-like Disorder With Loose Anagen Hair | Conjunctivitis | Klippel-Feil Syndrome | Paget's Disease Of The Breast | Fibromuscular Dysplasia | Peyronie's Disease | Spinal Cord Diseases | Hypoplastic Left Heart Syndrome | Facioscapulohumeral Muscular Dystrophy | Familial Glucocorticoid Deficiency | Acute Lymphocytic Leukemia | Nemaline Myopathy | Ischemia | Hepatitis | Charcot-Marie-Tooth Disease, Type 2C | Diffuse Intrinsic Pontine Glioma | Pemphigus Vulgaris | Retinal Detachment | Lichen Planus | Waardenburg Syndrome Type 2 | Muscle Wasting | Spondyloperipheral Dysplasia | Spasticity | Sleep Apnea, Obstructive | Aplastic Anemia | Lactose Intolerance | Chronic Thromboembolic Pulmonary Hypertension | Tetraplegia | Relapsing Polychondritis | Diffuse Mesangial Sclerosis | Sclerosteosis | Anemia | Arthropathy | Wolfram Syndrome | Perry Syndrome | Agranulocytosis | Connective Tissue Disorders | Epithelial-myoepithelial Carcinoma | Progressive Familial Intrahepatic Cholestasis Type 1 | Myhre Syndrome | Diabetes Insipidus | Dental Caries | Myasthenia | Menetrier Disease | Acute Coronary Syndrome | Methemoglobinemia | Metaphyseal Chondrodysplasia, Schmid Type | Multiple Hamartoma Syndrome | Treacher Collins Syndrome | Oligodendroglioma | Primary Aldosteronism | Takenouchi-Kosaki Syndrome | Papilloma | Majeed Syndrome | Headache | Cholestasis, Intrahepatic | Acute Kidney Injury | Chronic Leukemia | Endometriosis | Mood Disorder | Hypermethioninemia | Spina Bifida | Uveitis | Lymphoma Lymphoblastic | Ganglioglioma | Tracheal Disorders | Microphthalmia, Syndromic 7 | HUPRA Syndrome | Congenital Disorders Of Glycosylation | Lamellar Ichthyosis | Glycogen Storage Disease Type 9 | Hepatitis A | Pulmonary Capillary Hemangiomatosis | Charcot-Marie-Tooth Disease | Lyme Disease | Vitreoretinopathy, Proliferative | Crisponi Syndrome | Gingivitis | Wilson's Disease | Lesch-Nyhan Syndrome | Ovarian Hyperstimulation Syndrome | Hypersomnia | Keratitis-ichthyosis-deafness Syndrome | Spinocerebellar Ataxia Type 27 | Trachoma | Hereditary Spastic Paraplegia | Hepatorenal Syndrome | Bacterial Meningitis | Basal Ganglia Cerebrovascular Disease | Communication Disorders | Greenberg Dysplasia | Stomatitis | Adrenal Insufficiency | Erysipelas | Infectious Diarrhea | Erythema Nodosum | Glioblastoma | Prune Belly Syndrome | DiGeorge Syndrome | Fragile X Syndrome | Myoclonus-dystonia Syndrome | Alopecia | Meconium Ileus | Cataract | Hyperhomocysteinemia | Dystonia | Corneal Ulcer | Hyperparathyroidism | B-cell Prolymphocytic Leukemia | Bronchiectasis | Plasma Cell Leukemia | Keloid | Hyperbilirubinemia, Neonatal | Coffin-Siris Syndrome | Adenoma, Villous | Chorea-acanthocytosis | Congenital Sodium Diarrhea | Spitz Nevus | Epidermal Nevus Syndrome | Epidermolysis Bullosa Simplex, Localized | Usher Syndrome Type III | Down Syndrome | Spinocerebellar Ataxia Type 14 | Tendinitis | Iron Deficiency Anemia | Epidermolysis Bullosa Simplex, Generalized | Blue Rubber Bleb Nevus Syndrome | Cataplexy | Carney Triad | Lattice Corneal Dystrophy Type 1 | Adenoma, Pleomorphic | McCune-Albright Syndrome | Thrombocytopenia | Achromatopsia | Hyperparathyroidism, Secondary | Malaria, Cerebral | Hemangioma | Meningococcal Infections | Waardenburg Syndrome Type 4A | Silver-Russell Syndrome | Agammaglobulinemia | Mesothelioma, Malignant | Postpoliomyelitis Syndrome | Spinocerebellar Ataxia Type 31 | Pityriasis Rubra Pilaris | Ventricular Septal Defect | Proteus Syndrome | Sick Sinus Syndrome 1 | Ocular Albinism Type 1 | Fetal Alcohol Syndrome | Bartter Syndrome | Seizures-scoliosis-macrocephaly Syndrome | Carotid Artery Disease | Rhabdomyosarcoma | VACTERL/VATER Association | Periodontitis | VACTERL Association | Hyperostosis | Anti-glomerular Basement Membrane Disease | Xeroderma Pigmentosum | Spinocerebellar Ataxia Type 40 | Spastic Paraplegia Type 7 | Geleophysic Dysplasia | Von Hippel-Lindau Disease | Familial Mediterranean Fever | Ameloblastic Carcinoma | Acrocallosal Syndrome | Hypersensitivity Pneumonitis | Neurodevelopmental Disorders | Cat Eye Syndrome | Botulism | Congenital Generalized Lipodystrophy | Pemphigus | Congenital Tufting Enteropathy | Dominant Optic Atrophy | Persistent Fetal Circulation | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Nemaline Myopathy 10 | Hyperkalemic Periodic Paralysis | Bladder Exstrophy | Beare-Stevenson Syndrome | Kidney Stones | Heart Block | Multifocal Motor Neuropathy | Multiple Myeloma | Angioedema | Primary Familial Brain Calcification | Pelvic Inflammatory Disease | Cocaine-Related Disorders | Niemann-Pick Disease, Type C | Allergic Contact Dermatitis | Ellis-Van Creveld Syndrome | Nephrotic Syndrome | Arterial Tortuosity Syndrome | Polycystic Kidney, Autosomal Dominant | Osteogenesis Imperfecta Type I | Colitis, Collagenous | Familial Male-limited Precocious Puberty | Familial Partial Lipodystrophy | Adenocarcinoma | Glomerulonephritis, Membranous | Cheilitis | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Liver Failure, Acute Infantile | Asthma | Acromicric Dysplasia | Fibrosis | Arteriosclerosis | Uremia | Cole-Carpenter Syndrome | Castleman Disease | Seborrheic Dermatitis | Pulmonary Tuberculosis | Leri-Weill Dyschondrosteosis | Meningioma | Recurrent Respiratory Papillomatosis | Patent Foramen Ovale | Macular Corneal Dystrophy Type 1 | Depression | Craniosynostosis | Still Disease | Hepatitis, Alcoholic | Primary Pigmented Nodular Adrenocortical Disease | Dwarfism | Creutzfeldt-Jakob Disease | IMAGe Syndrome | Neuronal Ceroid Lipofuscinosis | Glutaric Aciduria Type 2 | Fatty Aldehyde Dehydrogenase Deficiency | Norrie Disease | Congenital Aniridia | Progressive Osseous Heteroplasia | Pseudohypoparathyroidism Type 1B | Oculocutaneous Albinism Type 1 | Glaucomatocyclitic Crisis | Polycystic Kidney, Autosomal Recessive | Epidermolytic Ichthyosis, Annular | Hypotrichosis Simplex | Neurofibroma, Plexiform | Chromosome 16p11.2 Deletion Syndrome | Miyoshi Myopathy | Situs Inversus | Juvenile Xanthogranuloma | Cabezas Syndrome | Myopathy | POEMS Syndrome | Distal Myopathy 2 | Mabry Syndrome | Sarcoidosis, Pulmonary | Presbycusis | Hemochromatosis | Liebenberg Syndrome | Cannabis Abuse | Adenoid Cystic Carcinoma | Hodgkin Lymphoma | Hepatic Steatosis | Anxiety Disorders | Compartment Syndrome | Neuroblastoma | Myofibrillar Myopathy | Perivascular Epithelioid Cell Tumor | Evans Syndrome | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Cryopyrin-associated Periodic Syndromes | Leishmaniasis, Cutaneous | Exocrine Pancreatic Insufficiency | Macrophage Activation Syndrome | Pyruvate Kinase Deficiency | Retinal Coloboma | Meckel-Gruber Syndrome | Epidermodysplasia Verruciformis | Allan-Herndon-Dudley Syndrome | DNA Ligase IV Deficiency | Gardner Syndrome | Esophageal Carcinoma | Prurigo Nodularis | Hereditary Xerocytosis | Gastric Atrophy | Hypercholesterolemia, Familial | Senior-Loken Syndrome | Gout | Glycogen Storage Disease Type 3 | Ophthalmia, Sympathetic | Cancer, Skin | Anorectal Malformations | Congenital Fiber-type Disproportion Myopathy | Frontotemporal Dementia | Pseudohermaphroditism | Fanconi Syndrome | Meleda Disease | Prediabetes | Branchiootorenal Syndrome | Apraxia | Juvenile Hyaline Fibromatosis | Nijmegen Breakage Syndrome | Cold-induced Sweating Syndrome | Tenosynovial Giant Cell Tumor | Congenital Absence Of Vas Deferens | Pouchitis | Keratosis | Benign Familial Pemphigus | Traboulsi Syndrome | Neurodermatitis | Hereditary Neuropathy With Liability To Pressure Palsies | Craniofacial Dysostosis | Leukocyte Adhesion Deficiency | Emery-Dreifuss Muscular Dystrophy | Localized Scleroderma | Peroxisomal Disorder | Alazami Syndrome | Low Tension Glaucoma | Diamond-Blackfan Anemia | Maple Syrup Urine Disease | Congenital Dyserythropoietic Anemia | Hemolytic Uremic Syndrome | Aldosterone Deficiency | Specific Granule Deficiency | Thyroid Dysgenesis | Hypertension, Essential | Chronic Mucocutaneous Candidiasis | Osteoglophonic Dysplasia | Glioblastoma Multiforme | FG Syndrome | Benign Familial Infantile Seizures | Chromosome 17q21.31 Deletion Syndrome | Eczema | Familial Dysautonomia | Leukocyte Adhesion Deficiency Type 1 | Myelitis, Transverse | Lipid Storage Diseases | Cyst | Urea Cycle Disorder | Neuromyelitis Optica | IgA Nephropathy | Spinocerebellar Ataxia Type 2 | Autism | Ichthyosis Hystrix, Curth-Macklin Type | Heterotopic Ossification | Trichomegaly | Niemann-Pick Disease, Type B | Transcobalamin Deficiency | Lymphopenia | Pycnodysostosis | Pontocerebellar Hypoplasia Type 2 | LMNA-related Congenital Muscular Dystrophy | Congenital Nephrotic Syndrome | Neonatal Progeroid Syndrome | Temporal Lobe Epilepsy | Ebstein Anomaly | Oculodentodigital Dysplasia | Episodic Ataxia | Smoldering Myeloma | Alexander Disease | Osteogenesis Imperfecta Type VI | Cartilage Disorders | Cutaneous T-cell Lymphoma | Cornelia De Lange Syndrome | Sitosterolemia | Otitis Media | Pulmonary Sclerosing Hemangioma | Autoimmune Polyendocrinopathy Syndrome Type I | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Shock, Cardiogenic | Common Cold | Fuchs Heterochromic Iridocyclitis | Retinopathy Of Prematurity | Neurofibroma | Blepharitis | Juvenile Polyposis | Myopia | Congestive Heart Failure | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Blastomycosis | Diffuse Palmoplantar Keratoderma | Deafness, Dystonia, And Cerebral Hypomyelination | Motor Neuron Diseases | Krabbe Disease | Multiple Sclerosis, Chronic Progressive | Rothmund-Thomson Syndrome | Leiomyoma | Myocardial Infarction | Fibronectin Glomerulopathy | Cholelithiasis | Hereditary Elliptocytosis