Hypoplastic Left Heart Syndrome

About the Disease
Hypoplastic Left Heart Syndrome, also known as hlhs, is related to aortic valve disease 2 and aortic valve disease 1. An important gene associated with Hypoplastic Left Heart Syndrome is TBX20 (T-Box Transcription Factor 20), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Neural crest differentiation. The drugs Ambrisentan and Sildenafil have been mentioned in the context of this disorder. Affiliated tissues include heart, skin and brain, and related phenotypes are hypoplastic left heart and hypoplastic aortic arch

Common Targets
G4851 | ADRA2A | FOXP1 | NKX2-5 | RAF1 | ADRB1 | HMCN1 | TBX5 | PTPRB | NR2F2 | MYH6 | FOXL1 | FOXC2 | HEYL | HEY2 | MYH7 | MYRF

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