Creatine Deficiency Syndrome Due To AGAT Deficiency

About the Disease
Cerebral Creatine Deficiency Syndrome 3, also known as arginine:glycine amidinotransferase deficiency, is related to cerebral creatine deficiency syndrome 1 and type 2 diabetes mellitus. An important gene associated with Cerebral Creatine Deficiency Syndrome 3 is GATM (Glycine Amidinotransferase), and among its related pathways/superpathways are Metabolism and Regulation of expression of SLITs and ROBOs. Affiliated tissues include brain and whole blood, and related phenotypes are gowers sign and intellectual disability

Common Targets
GATM

Note: If you'd like to get a target analysis report for Creatine Deficiency Syndrome Due To AGAT Deficiency, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Creatine Deficiency Syndrome Due To AGAT Deficiency at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Pulverulent Zonular Cataract | Okihiro Syndrome | Leukoplakia | 3-hydroxy-3-methylglutaric Aciduria | Epidermolysis Bullosa Simplex, Localized | GLUT1 Deficiency Syndrome | Carney-Stratakis Syndrome | Reye Syndrome | Narcolepsy | Hereditary Inclusion Body Myopathy | Gitelman Syndrome | Autonomic Neuropathy | Achondrogenesis | Fragile X Syndrome | Myofibromatosis | Gestational Trophoblastic Disease | Portal Vein Thrombosis | Giant Axonal Neuropathy | Melanoma, Malignant | Asphyxia Neonatorum | Hypoproteinemia, Hypercatabolic | Retinitis | Primary Sclerosing Cholangitis | Meleda Disease | Werner's Syndrome | Chromosome 5q Deletion Syndrome | Eccrine Porocarcinoma | Acromesomelic Dysplasia | Mannosidase Deficiency Diseases | Thyroid Dyshormonogenesis | Trichuriasis | Neuromyotonia | Intellectual Disability, Autosomal Dominant 5 | Congenital Hereditary Endothelial Dystrophy Type I | Glycogen Storage Disease | Glaucoma | Diabetes Insipidus, Neurogenic | Myoclonus-dystonia Syndrome | 3-M Syndrome | Facioscapulohumeral Muscular Dystrophy Type 2 | Tatton-Brown-Rahman Syndrome | Anemia | Azoospermia | Chordoma | Generalized Epilepsy And Paroxysmal Dyskinesia | Non-proliferative Diabetic Retinopathy | ADNP Syndrome | Wolff-Parkinson-White Syndrome | Gastric Atrophy | Adams-Oliver Syndrome | Antiphospholipid Syndrome | Oculodentodigital Dysplasia | Mohr-Tranebjaerg Syndrome | Omenn Syndrome | Malaria, Cerebral | Vascular Calcification | Optic Atrophy 2 | Facioscapulohumeral Muscular Dystrophy Type 1 | Lamellar Ichthyosis | Spinocerebellar Ataxia Type 5 | Measles | Pheochromocytoma | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Congenital Fiber-type Disproportion Myopathy | Zimmermann-Laband Syndrome | Retinal Vasculitis | Prune Belly Syndrome | Spinal And Bulbar Muscular Atrophy | Hypercholesterolemia, Familial | Takotsubo Cardiomyopathy | Polydactyly | Spina Bifida | Thrombophilia | Lung Diseases | Achromatopsia | Cutaneous Mastocytosis | Keloid | Hemosiderosis | Cramp Fasciculation Syndrome | H Syndrome | Hepatorenal Syndrome | Congenital Afibrinogenemia | Spinocerebellar Ataxia Type 23 | Wagner Disease | Polymyositis | Arthritis, Reactive | Mucolipidosis Type II | Facioscapulohumeral Muscular Dystrophy | Torticollis | Hereditary Coproporphyria | Hypoalbuminemia | Common Cold | Multiple Sulfatase Deficiency | T-cell Leukemia | Juvenile Xanthogranuloma | Liver Failure | Pantothenate Kinase-associated Neurodegeneration | Syphilis | Adenocarcinoma | Primary Erythromelalgia | Hereditary Folate Malabsorption | Rubinstein-Taybi Syndrome | Hyperuricemia | Neuromuscular Disorders | Glycogen Storage Disease Type 0, Muscle | Megaloblastic Anemia | Aicardi-Goutieres Syndrome | Connective Tissue Disorders | Cantu Syndrome | Leishmaniasis, Cutaneous | IgA Nephropathy | Beta-Propeller Protein-associated Neurodegeneration | Esophageal Motility Disorders | Inflammatory Myopathy | Phenylketonuria | Auriculocondylar Syndrome | Fabry's Disease | Chediak-Higashi Syndrome | Ectrodactyly | Amyotrophic Lateral Sclerosis | Kidney Stones | Hepatic Adenomatosis | Non-Hodgkin Lymphoma | Thanatophoric Dysplasia Type 1 | Endophthalmitis | Guillain-Barre Syndrome | Mesothelioma, Malignant | Insulin Resistance | ACTH-independent Macronodular Adrenal Hyperplasia | Potocki-Shaffer Syndrome | Lipid Storage Myopathy | Primrose Syndrome | Congenital Mirror Movements | Dubin-Johnson Syndrome | Pontocerebellar Hypoplasia Type 2 | Harlequin Ichthyosis | Neurocutaneous Syndromes | Hypolipoproteinemia | Agranulocytosis | Tardive Dyskinesia | Autosomal Recessive Bestrophinopathy | Zollinger-Ellison Syndrome | Hidradenitis Suppurativa | Myotonia | Gingivitis | Hypopituitarism | Camptocormia | ICF Syndrome | Pre-eclampsia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Perivascular Epithelioid Cell Tumor | Primary Lateral Sclerosis | Nemaline Myopathy 10 | Fahr Disease | Kawasaki Disease | Sotos Syndrome | Chylomicron Retention Disease | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Hypobetalipoproteinemias | X-linked Acrogigantism | Aneurysm, Thoracic Aortic | Spinocerebellar Ataxia Type 40 | Senior-Loken Syndrome | Tietze Syndrome | Osteomalacia | Vaginitis | Renal Hypomagnesemia 3 | Dystonia Musculorum Deformans | Non-epidermolytic Palmoplantar Keratoderma | Congenital Bilateral Absence Of Vas Deferens | Dyggve-Melchior-Clausen Disease | Intracranial Hypertension | POEMS Syndrome | Polycythemia | Schindler Disease | Chronic Myeloid Leukemia | Hypertelorism | Hypothyroidism | Methemoglobinemia Type IV | Mitochondrial Disease | Histoplasmosis | Myosin Storage Myopathy | Progressive External Ophthalmoplegia | Hemolytic Uremic Syndrome, Atypical | Spinocerebellar Ataxia | DRESS Syndrome | Pericarditis | Richter's Syndrome | Antisynthetase Syndrome | Gray Platelet Syndrome | Eosinophilic Asthma | Bleeding Disorder Due To CalDAG-GEFI Deficiency | L-2-Hydroxyglutaric Aciduria | Anterior Segment Dysgenesis | Pyruvate Kinase Deficiency | Focal Cortical Dysplasia Type 2 | Lathosterolosis | Rubeosis Iridis | Juvenile Polyposis | Pain | Mucolipidosis | Dominant Optic Atrophy | Primary Hyperoxaluria | Ollier Disease | Autoimmune Polyendocrine Syndrome | Loeys-Dietz Syndrome | Myasthenia | Myasthenia Gravis | Aphasia | Spinocerebellar Ataxia Type 6 | Metachromatic Leukodystrophy | Unverricht-Lundborg Syndrome | Palmoplantar Keratoderma | Wieacker-Wolff Syndrome | Early Infantile Epileptic Encephalopathy 13 | Pigment Dispersion Syndrome | Microphthalmia | Bacterial Meningitis | Melanoma, Uveal | Hyperuricemic Nephropathy, Familial Juvenile | Swine Influenza | Spinocerebellar Ataxia Type 8 | Hyperparathyroidism, Primary | Brachial Plexus Neuropathy | Hydrocephalus | Dystonia | Bare Lymphocyte Syndrome | Congenital Lipoid Adrenal Hyperplasia | Pulmonary Sclerosing Hemangioma | Gyrate Atrophy Of The Choroid And Retina | Anti-glomerular Basement Membrane Disease | Pulmonary Alveolar Microlithiasis | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Klippel-Feil Syndrome | Hereditary Elliptocytosis | Cystinosis | Hereditary Mixed Polyposis Syndrome | Gastroschisis | Hoyeraal-Hreidarsson Syndrome | Amelogenesis Imperfecta | Non-Langerhans Cell Histiocytosis | Infertility | Fibrosarcoma | Ganglioneuroma | Seizures | Hyperferritinemia-cataract Syndrome | Riboflavin Transporter Deficiency Neuronopathy | Postaxial Polydactyly | Schizophrenia | McKusick Type Metaphyseal Chondrodysplasia | Aplasia Cutis Congenita | Astigmatism | VACTERL Association | Brachydactyly | Snyder-Robinson Syndrome | Ichthyosis, X-linked | Tuberculosis | Hydrolethalus Syndrome | Nephropathy | Arteriosclerosis | Stomatitis | Reflex Epilepsy | Hypercholesterolemia | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Alpha-1 Antitrypsin Deficiency | Corneal Dystrophies, Hereditary | Gerodermia Osteodysplastica | Fundus Albipunctatus | Familial Advanced Sleep Phase Syndrome | Retinopathy Of Prematurity | Endometrial Hyperplasia | Hypermetropia | Motor Neuron Diseases | Behavioral Variant Of Frontotemporal Dementia | Posterior Polar Cataract | Bullous Pemphigoid | Proopiomelanocortin Deficiency | Stroke | Prurigo Nodularis | Beckwith-Wiedemann Syndrome | Medulloblastoma | Carcinoma, Signet Ring Cell | COACH Syndrome | Peripheral T-cell Lymphoma | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Myhre Syndrome | Spinocerebellar Ataxia Type 7 | 5-oxoprolinase Deficiency | Carcinoma, Small Cell | Fibromuscular Dysplasia | Sarcoma, Endometrial Stromal | Chronic Neutrophilic Leukemia | Congenital Disorders Of Glycosylation Type II | Guttate Psoriasis | Hypereosinophilic Syndrome | Niemann-Pick Disease, Type A | Restrictive Dermopathy | Neutropenia | Polycystic Ovary Syndrome | Neuromyelitis Optica | Neuroblastoma | Porencephaly | Cushing Syndrome | Colorectal Adenoma | Alopecia | Hereditary Sensory Neuropathy Type 1 | Barakat Syndrome | Spinocerebellar Ataxia Type 31 | Rheumatic Heart Disease | Muscular Dystrophy | Erythema Nodosum | Congenital Dysfibrinogenemia | Osteosclerosis | Necrotizing Autoimmune Myopathy | Sepiapterin Reductase Deficiency | Schnitzler Syndrome | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Protein C Deficiency | Dental Caries | Uterine Leiomyoma | Retinoblastoma | Lymphedema | Splenomegaly | Hypotonia-cystinuria Syndrome | Systemic Mastocytosis | Congenital Nephrotic Syndrome | Vascular Cognitive Impairment | Arts Syndrome | Chondromyxoid Fibroma | Neovascular Glaucoma | Sialoadenitis | Orthostatic Intolerance | Infantile Spasm | Rhabdoid Tumor | Atrioventricular Septal Defect | Spondyloarthritis | Parkinson Disease 6, Autosomal Recessive Early-onset | Tyrosine Hydroxylase Deficiency | Schuurs-Hoeijmakers Syndrome | Hennekam Lymphangiectasia-lymphedema Syndrome | Metatropic Dysplasia | Ocular Albinism Type 1 | Down Syndrome | Usher Syndrome Type I | Hidradenitis | Prediabetes | Argininosuccinic Aciduria | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Chromosome 9q34.3 Deletion Syndrome | Leber Congenital Amaurosis | Precocious Puberty | Mitochondrial Myopathy | Cholera | Common Variable Immunodeficiency | Graft-versus-host Disease | Lymphoma, AIDS-related | Myelitis, Transverse | Acne Vulgaris | Congenital Generalized Lipodystrophy | Intestinal Tuberculosis | Cholecystitis | Sleep Apnea, Central | Cockayne Syndrome | Endometritis | Congenital Absence Of Vas Deferens | Tracheal Disorders | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Granular Corneal Dystrophy | Von Hippel-Lindau Disease | Phenylketonuria II | Poretti-Boltshauser Syndrome | Sporadic Hemiplegic Migraine | Uveitis, Anterior | Hemorrhoids | Purpura, Thrombotic Thrombocytopenic | Hyperacusis | Fetal Akinesia Deformation Sequence | Congenital Heart Defects | Hepatopulmonary Syndrome | Familial Thoracic Aortic Aneurysm | Holt-Oram Syndrome | Cutaneous Angiosarcoma | LRBA Deficiency | Acrodysostosis | Myelodysplasia | Actinomycetoma | Jacobsen Syndrome | Impetigo | Maternally Inherited Diabetes And Deafness | Hyperekplexia | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Lymphangioma | Paraplegia | Angiosarcoma | Autoimmune Hemolytic Anemia | Sleep Disorder | Spondylo-ocular Syndrome | Myositis | Diabetes Type 1 | Cherubism