Non-Hodgkin Lymphoma

About the Disease
Lymphoma, also known as non-hodgkin malignant lymphoma nos, is related to lymphoma, hodgkin, classic and lymphoma, non-hodgkin, familial. An important gene associated with Lymphoma is PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11), and among its related pathways/superpathways are IL-9 Signaling Pathways and NF-kappaB Signaling. The drugs Ferrous succinate and Posaconazole have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and myeloid, and related phenotypes are immune system and hematopoietic system

Common Targets
MSH6 | APEH | BAG6 | G238 | MSH2 | G5347 | GSTP1 | CCR3 | TNFRSF9 | JAK3 | ADAM10 | CCL26 | TNFRSF10B | IL2RB | JAK1 | PIK3CG | FAM110B | SIRT2 | HLA-DQB1 | G596 | CXCR5 | KDR | MPO | FCGR2B | BIVM-ERCC5 | CEBPE | NTRK2 | NT5C2 | CSNK1E | KCNH2 | DNA Methyltransferase (DNMT) (nonspecified subtype) | PARP3 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | ERCC5 | G472 | NBN | CD74 | Cyclin B (nonspecified subtype) | MDM4 | Protein farnesyltransferase | AURKA | G1956 | SNCA | ABL1 | DNA-Directed DNA Polymerase Complex | GTF2H1 | HDAC10 | GSR | OGDH | MALT1 | IL-15 receptor | JAK2 | IL12B | FAP | FBN1 | G6774 | Pyruvate Dehydrogenase Complex | THBS1 | HLA-DMB | CCR6 | ASXL1 | MYD88 | CDK2 | IL1RN | G3569 | G7015 | TFRC | ORAI1 | CCNH | NFATC1 | HDAC2 | TNFRSF10A | BTK | CTPS1 | HOXA9 | NAE1 | FAM221A | Heat shock protein 90 (nonspecified subtype) | PRMT5 | HOXB13 | PRDM1 | CNRIP1 | IFNGR1 | ELANE | G5563 | Calcium release-activated channel (CRAC) | PRKCA | CDK6 | IL2RA | CHEK1 | MNX1 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | CCR4 | CCR7 | AURKB | G6352 | C11orf65 | AXL | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | G7099 | LAG3 | BMX | Ribonucleoside-diphosphate reductase | Protein kinase C (nonspecified subtype) | MSH5 | VWA5B1 | GATA6 | EED | TYK2 | EML4 | HLA class II histocompatibility antigen DR (HLA-DR) | G1950 | G5133 | EBF3 | G598 | PIM3 | TNFSF13B | CD3 Complex (T Cell Receptor Complex) | mTOR complex 1 | G7295 | IL7R | CDK4 | CD2 | CCL7 | KIT | ADAM17 | TOP1 | IKZF1 | G29126 | HLA-B | CDK9/Cyclin T1 | FLRT2 | LY75 | HDAC11 | NOD2 | NOTCH4 | BRCA2 | CCL8 | G7852 | CACNG8 | NCF4 | DPP7 | BCR | MAP2K1 | DRD2 | XIAP | RHOH | BRD4 | ZNF503 | HLA-DRB1 | PIK3CD | AVEN | TGFB1I1 | NRN1 | DPP8 | MAL | PLXNC1 | IFNGR2 | Adenosine deaminase (nonspecified subtype) | DNA Topoisomerase II (nonspecified subtype) | ARID5B | ROS1 | CCN2 | FOXP4 | GABRG3 | CDK9 | ADA | HDAC3 | IRF4 | POLQ | SH3BP4 | FZD8 | MSI1 | CCL11 | XPO1 | ZAP70 | CD40 | SIRPA | SOD2 | CD52 | CD38 | INA | G142 | Interleukin-12 (IL-12) | NTRK3 | SEPTIN9 | DPP4 | PDGFRB | CD22 | HLA-DRA | SYK | G581 | PIKFYVE | CCL13 | Tyrosine Kinase (nonspecified subtype) | HDAC1 | JUP | G4170 | MUC1 | CCNT1 | CDK20 | ITGA5 | LSP1 | EZH1 | PTGS1 | SUMO activating enzyme complex | FABP5 | FCGR3A | CCR8 | PRF1 | PAX5 | DSP | MRE11 | G4609 | FCRL2 | NEDD8-activating enzyme E1 | TMEM260 | AIF1 | NTRK1 | SYT6 | IL5 | CCL1 | HEATR9 | HLA-A | Interferon alpha/beta Receptor (nonspecified subtype) | CSNK1A1 | CD7 | G9429 | BCL2A1 | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | BCL2L11 | CD70 | Polycomb Repressive Complex 2 | TNFAIP3 | G2475 | MS4A1 | CDK1/Cyclin B | MERTK | CCR9 | G3480 | FLT4 | mTOR complex 2 | CCND3 | CCR1 | MSMB | IKZF3 | KIF11 | G2033 | ADRA1D | KDM1A | CCL18 | Mitogen-Activated Protein Kinase (nonspecified subtype) | CD80 | PRKAG1 | FLT1 | H1-3 | TYRO3 | RAD51 | CDK2/Cyclin A | CD3E | HLA-DRB3 | TNFRSF13C | BCL2L2 | RYR3 | ROR1 | NR3C1 | BLK | G7157 | Ikzf1 | CLPTM1L | TNFRSF17 | B2M | CCL20 | CLPP | Janus Kinase (nonspecified subtype) | PRKCB | Glutaminase (nonspecified subtype) | MBP | PIM1 | VCP | FCGR2A | NPAT | PON1 | POLA1 | CXCR2 | METAP2 | LYN | SPART | TIMP2 | TIGIT | Tubulin | MMP2 | MAP2K2 | G5743 | CD79B | TLR9 | PPP1R14A | Cyclin A (nonspecified subtype) | EPHX1 | VDR | NAMPT | CCL24 | PARP2 | TNFRSF8 | TYMS | CTLA4 | HLA-DRB5 | PIK3CA | CD47 | CD28 | CCR5 | PAK4 | CD37 | MYCN | G2064 | GSPT1 | G7124 | KMT2D | NQO1 | LGALS1 | CREBBP | PRRC2A | DPP9 | BIRC5 | GPER1 | 11beta-Hydroxysteroid Dehydrogenase (nonspecified subtype) | DNAH14 | PDGFRA | FLT3 | DHFR | TNFRSF13B | TDP1 | PTPRC | IL10 | ATR | IL6R | MTHFR | DRD3 | FCRL5 | TAP2 | MTR | Proteasome Complex | TOP2A | ALDH1L1 | Histone deacetylase (nonspecified subtype) | G2146 | TOGARAM1 | G5243 | CDK1 | PTPRO | ASRGL1 | CDK7 | C2 | G7422 | POU2AF1 | CD19 | GOLGA7

Note: If you'd like to get a target analysis report for Non-Hodgkin Lymphoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Non-Hodgkin Lymphoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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