Disease

Chondrosarcoma

About the Disease
Chondrosarcoma, also known as cartilaginous cancer, is related to chondrosarcoma, extraskeletal myxoid and myxoid chondrosarcoma. An important gene associated with Chondrosarcoma is EXT1 (Exostosin Glycosyltransferase 1), and among its related pathways/superpathways are Interleukin-4 and Interleukin-13 signaling and Proteoglycan biosynthesis. The drugs Mechlorethamine and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include bone, t cells and brain, and related phenotype is chondrosarcoma.

Common Targets
RAD51D | IDH1 | G4609 | ACAN | ARHGAP35 | ETV3 | G5594 | CIC | CASP8 | Hedgehog Protein (nonspecified subtype) | RAD52 | NTRK1 | LRATD2 | PTCH1 | NOTCH4 | TP73 | G7015 | CTLA4 | G7157 | TSHZ3 | CUL4B | SLC4A1 | GART | PRX | PDGFRA | FAT3 | SUZ12 | APC | KIT | RB1 | CUL4A | MEN1 | KMT2A | JAK1 | RAD50 | IDH2 | RPS14 | KIF5B | CREBBP | TYMS | TOP2A | FOXA2 | MIR181A1 | G1029 | SIK1 | DHFR | EPHA5 | G5728 | PDGFRB | NAPRT | ATR | G2475 | HIF1A | HDAC6 | EPAS1 | G5243 | SMC3 | MED12 | TNFRSF10B | TSC1 | SMO | MAPK8IP1 | NOTCH3 | NCOR1 | G4851 | SPEN | RAD54L | G9429 | FKBP1A | ARID1B | KDR | FLT1 | FLT4

疾病靶点研报
Chondrosarcoma

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