McCune-Albright Syndrome

About the Disease
Mccune-Albright Syndrome, also known as polyostotic fibrous dysplasia, is related to fibrous dysplasia and acth-independent cushing syndrome. An important gene associated with Mccune-Albright Syndrome is GNAS (GNAS Complex Locus), and among its related pathways/superpathways are Metabolism of proteins and ERK Signaling. The drugs Etidronic acid and Risedronic acid have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and thyroid, and related phenotypes are fibrous dysplasia of the bones and precocious puberty

Common Targets
Estrogen receptor (nonspecified subtype) | GNAS | FGF23 | CYP19A1 | PRKACA

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