Disease

Photosensitivity

About the Disease
Photoparoxysmal Response 1, also known as photosensitivity disease, is related to porphyria, congenital erythropoietic and protoporphyria, erythropoietic, 1, and has symptoms including exanthema, pruritus and photophobia. An important gene associated with Photoparoxysmal Response 1 is PPR1 (Photoparoxysmal Response 1), and among its related pathways/superpathways are superpathway of b heme biosynthesis from glycine and "Platinum Pathway, Pharmacokinetics/Pharmacodynamics". The drugs Fluorouracil and Diclofenac have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and retina, and related phenotypes are eeg with photoparoxysmal response and Increased shRNA abundance (Z-score > 2)

Common Targets
G7099 | PKMYT1 | CHEK1 | LOC102724428 | TIRAP | G3605 | ERCC2 | G836 | CDK1/Cyclin B | G5243 | SIK2 | PRKCB | TLR9 | NOX1 | SIK1 | Serine/Threonine-Protein Kinase PLK (nonspecified subtype) | CDK1 | FCER1A | SIK3 | CR2

疾病靶点研报
Photosensitivity

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