Disease

Late Onset Alzheimer Disease

About the Disease
Alzheimer Disease 2, also known as alzheimer disease associated with apoe4, is related to alzheimer disease 3 and sleep disorder. An important gene associated with Alzheimer Disease 2 is APOE (Apolipoprotein E), and among its related pathways/superpathways are Metabolism of proteins and Neuroscience. The drugs BCG vaccine and Eltanolone have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and temporal lobe, and related phenotypes are dementia and parkinsonism

Common Targets
CASP7 | UCP3 | PLD3 | CETP | MC1R | MLKL | PSEN1 | TOMM40 | TGFB1 | ABI3 | AKAP9 | SLC25A27 | CTNNA1 | NR1H2 | ABCA7 | LOC105373336 | ACE | PLEKHG6 | SNRNP200 | ADIPOQ | TYK2 | MIEF1 | NME8 | MS4A6A | GAS2L2 | TM2D3 | GSTO1 | IL7R | TCF4 | HMGCR | NOTCH4 | RPGRIP1 | EPHA1 | GALR3 | ADAM17 | BTNL2 | CLU | CACNA1C | PPARG | PCSK9 | G4137 | MEF2C | G999 | FERMT2 | ITGA4 | GSTT1 | C3AR1 | OPRL1 | CSMD1 | TREM2 | CLECL1P | PTK2B | ZCWPW1 | LOC102724808 | VWA2 | ND3 | MEF2C-AS1 | ZXDC | RAB38 | CYP39A1 | SHARPIN | MTCH2 | MFN2 | MME | B3GALT4 | CT47B1 | SMOX | CD33 | CYP2J2 | UNC5C | CR1 | CD163L1 | RTN3 | LAMA1 | IL16 | MTHFR | GRK5 | TTLL2 | NEIL1 | ND4L | PPP2R3A | ECE1 | LRP1B | GSTM1 | OPA1 | GSTP1 | DNAJB13 | TYROBP | SORL1 | CLHC1 | PTGR3 | POLB | TRIML2 | IDE | APOE | IL1B | MS4A4E | G3569 | UNG | INPP5D | UCP2 | SLC25A14 | PLCG2 | SKAP2 | ADAM10 | CYBA

疾病靶点研报
Late Onset Alzheimer Disease

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