Porokeratosis

About the Disease
Porokeratosis, also known as disseminated superficial actinic porokeratosis, is related to porokeratosis 1, multiple types and linear porokeratosis. An important gene associated with Porokeratosis is SLC17A9 (Solute Carrier Family 17 Member 9), and among its related pathways/superpathways are Metabolism of steroids and Regulation of actin cytoskeleton. The drugs Lovastatin and Lipid Regulating Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, bone marrow and hypothalamus, and related phenotypes are hyperkeratosis and porokeratosis

Common Targets
PMVK | MVD | MVK | FDPS | SLC17A9 | GJB2

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