Spondylocarpotarsal Synostosis Syndrome

About the Disease
Spondylocarpotarsal Synostosis Syndrome, also known as vertebral fusion with carpal coalition, is related to synostosis and atelosteogenesis. An important gene associated with Spondylocarpotarsal Synostosis Syndrome is FLNB (Filamin B), and among its related pathways/superpathways are Cardiac conduction and Striated muscle contraction pathway. Affiliated tissues include bone, eye and skin, and related phenotypes are abnormality of retinal pigmentation and frontal bossing

Common Targets
PXK | SCN7A | CHST3 | MYH3 | RFLNA | FLNB | COL21A1

Note: If you'd like to get a target analysis report for Spondylocarpotarsal Synostosis Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Spondylocarpotarsal Synostosis Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Reflex Epilepsy | Diastrophic Dysplasia | Progressive Familial Intrahepatic Cholestasis Type 2 | Primary Lateral Sclerosis | Cohen Syndrome | Multiple Sclerosis, Primary Progressive | Peyronie's Disease | Androgen Insensitivity | Gastric Atrophy | Glycogen Storage Disease Type 4 | Milk Allergy | Genitopatellar Syndrome | Thrombosis | Creutzfeldt-Jakob Disease | Hyperparathyroidism, Primary | Pseudoexfoliation Syndrome | Rhinitis | Sickle Cell Anemia | Paraganglioma, Carotid Body | Macular Degeneration | Erectile Dysfunction | Hypoplastic Left Heart Syndrome | Lymphoma | Basal Ganglia Disease, Biotin-responsive | Heart Septal Defects | Erythematotelangiectatic Rosacea | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Spinal And Bulbar Muscular Atrophy | Huntington's Disease | Primary Aldosteronism | Porphyria Cutanea Tarda | Xeroderma Pigmentosum Variant Type | Gastroenteritis | HIBCH Deficiency | Thalassemia, Beta | Blue Nevus | Diffuse Palmoplantar Keratoderma | Behavioral Variant Of Frontotemporal Dementia | Neuropathy | Varicocele | Myocardial Infarction | Spinocerebellar Ataxia Type 17 | POEMS Syndrome | Adenoma, Pleomorphic | Autosomal Recessive Spastic Paraplegia Type 35 | Myositis, Focal | Nevus | Juvenile Polyposis | Cannabis Abuse | Schistosomiasis | Myasthenia Gravis | DICER1 Syndrome | Hemolytic Anemia | Schwannomatosis | Encephalopathy, Hepatic | Dominant Optic Atrophy | Neurofibroma | Persistent Hyperplastic Primary Vitreous | Scapuloperoneal Spinal Muscular Atrophy | Citrullinemia | Tinea | Hypoproteinemia, Hypercatabolic | Adrenoleukodystrophy, X-linked | Peroxisomal Disorder | Atherosclerosis | Prostatitis | PASLI Disease | Tracheal Disorders | Spondylo-ocular Syndrome | Gastritis | Dyslexia | T-cell Chronic Lymphocytic Leukemia | Congenital Dyserythropoietic Anemia Type 1 | Personality Disorders | Apraxia | Cyclic Vomiting Syndrome | Carney Triad | Acute Coronary Syndrome | Empyema | Adult Polyglucosan Body Disease | Adenoma, Pituitary | Distal Myopathy 2 | Angelman Syndrome | Coma | Pituitary Stalk Interruption Syndrome | Eccrine Porocarcinoma | Polymyalgia Rheumatica | Encephalocele | Cutaneous Mastocytosis | Agoraphobia | Mevalonate Kinase Deficiency | Heart Block | HELLP Syndrome | Myelitis, Transverse | Hyperinsulinism-hyperammonemia Syndrome | Chiari Malformation Type I | Axenfeld-Rieger Syndrome | Richter's Syndrome | Danon Disease | Macrodactyly | Pneumonia, Mycoplasma | Cranial Nerve Disease | Pompe Disease | Bronchiolitis | Mitochondrial Myopathy | Primary Progressive Nonfluent Aphasia | Cystinuria | Stickler Syndrome | Haim-Munk Syndrome | Spinocerebellar Ataxia Type 28 | Diverticulitis | Autism | Cenani-Lenz Syndactyly Syndrome | Infantile Neuroaxonal Dystrophy | Retinal Vasculitis | Central Retinal Artery Occlusion | Retinoschisis | C3 Glomerulonephritis | Fetal And Neonatal Alloimmune Thrombocytopenia | Centronuclear Myopathy | Iron Overload | Adenocarcinoma | Glycogen Storage Disease Type 1b | Hepatitis A | Muscle Wasting | Pulmonary Alveolar Microlithiasis | Cantu Syndrome | Tuberculous Meningitis | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Acute Lung Injury | Mucolipidosis Type IV | Mumps | Polycystic Kidney, Autosomal Recessive | CREST Syndrome | Coronary Restenosis | Neurofibromatosis | Greig Cephalopolysyndactyly Syndrome | Succinic Semialdehyde Dehydrogenase Deficiency | Peters-plus Syndrome | Amelogenesis Imperfecta | Vascular Cognitive Impairment | Hyper IgE Syndrome | Acromicric Dysplasia | Porphyria, Variegate | Long QT Syndrome Type 1 | Hypercalciuria | Osteogenesis Imperfecta Type II | Parkinsonism | Hemorrhage | Pseudo-pseudohypoparathyroidism | Renpenning Syndrome | Cryptorchidism | Lissencephaly 2 | Chondrodysplasia Punctata 1, X-linked Recessive | Galactosemia | Androgenic Alopecia | Charcot-Marie-Tooth Disease, Type 6 | Vitamin B12 Deficiency | Osteogenesis Imperfecta Type VI | Spinocerebellar Ataxia Type 3 | Neurocutaneous Syndromes | Primary Progressive Aphasia | Occipital Neuralgia | Adams-Oliver Syndrome | Osteonecrosis | Fanconi Syndrome | Endometriosis | Auriculocondylar Syndrome | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Pitt-Hopkins Syndrome | Meesmann Corneal Dystrophy | Dubin-Johnson Syndrome | Megalencephaly | Raynaud Phenomenon | Necrotizing Autoimmune Myopathy | Rolandic Epilepsy | Ophthalmia, Sympathetic | Cutis Laxa | Fascioliasis | Arts Syndrome | Guttate Psoriasis | Cervicitis | Thrombasthenia | Herpes Simplex Dermatitis | Leishmaniasis, Visceral | Oral Lichen Planus | Miyoshi Myopathy | Hereditary Folate Malabsorption | Neurofibroma, Plexiform | Irritable Bowel Syndrome | Alpers Syndrome | Cardiospondylocarpofacial Syndrome | Hyperlipidemia, Familial Combined | Pontocerebellar Hypoplasia Type 7 | Nasodigitoacoustic Syndrome | Optic Neuritis | Urethritis | Retinitis | Gyrate Atrophy Of The Choroid And Retina | Dysfibrinogenemia | Moyamoya Disease | Aldosterone Deficiency | Low Tension Glaucoma | Arthrogryposis | Charcot-Marie-Tooth Disease Type 3 | Autoimmune Polyendocrinopathy Syndrome Type I | Papillorenal Syndrome | Gangliosidosis, GM1 | Dyggve-Melchior-Clausen Disease | Platelet Disorders | Angiosarcoma | Usher Syndrome Type I | Chronic Inflammatory Demyelinating Polyneuropathy | Infertility | Hyperekplexia | Porphyria | Fabry's Disease | Ataxia-ocular Apraxia 2 | Blomstrand Osteochondrodysplasia | Charcot-Marie-Tooth Disease Type 2D | Pheochromocytoma | Nephrotic Syndrome Type 1 | Overactive Bladder | Norrie Disease | Retinal Degeneration | Tonsillitis | Sleep Apnea | Schizotypal Personality Disorder | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Renal Failure | Lamellar Ichthyosis | Wiedemann-Steiner Syndrome | Infantile Refsum Disease | Addison Disease | Hypersensitivity Pneumonitis | Congenital Adrenal Hyperplasia 1 | Multiple Hamartoma Syndrome | Hereditary Hemorrhagic Telangiectasia Type 2 | SAPHO Syndrome | Hereditary Pyropoikilocytosis | Thyroiditis, Autoimmune | Pseudohypoparathyroidism Type 1B | Esotropia | Hypercholesterolemia, Familial | Spinocerebellar Ataxia Type 14 | Colorectal Adenoma | Synovitis | Epilepsy Of Infancy With Migrating Focal Seizures | Common Cold | Porphyria, Acute Intermittent | Hermansky-Pudlak Syndrome | Cerebellofaciodental Syndrome | Early Infantile Epileptic Encephalopathy | GATA2 Deficiency | Borderline Personality Disorder | Crohn's Disease | Menkes Disease | Hepatitis, Chronic | Agammaglobulinemia | Nemaline Myopathy 8 | Reticular Dysgenesis | Echinococcosis | Primary Erythromelalgia | Lymphomatoid Granulomatosis | AIDS | IMAGe Syndrome | Insulinoma | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Gynecomastia | Malnutrition | Hyperuricemic Nephropathy, Familial Juvenile | Chylomicron Retention Disease | Heart Failure | Hyperphenylalaninemia | Hypertension | Benign Hereditary Chorea | Vitreoretinal Degeneration, Snowflake Type | Hydronephrosis | Eiken Syndrome | Primary Cutaneous Amyloidosis | Blue Rubber Bleb Nevus Syndrome | Insulin Resistance | Fibrosis | Cholangitis | Pituitary Dwarfism | Bietti Crystalline Dystrophy | Carbohydrate Metabolism Disorders | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Paraganglioma | Hennekam Lymphangiectasia-lymphedema Syndrome | Leiomyoma | Wolfram Syndrome | Spinocerebellar Ataxia Type 38 | Apert Syndrome | Neurofibromatosis Type 2 | Central Core Disease | Myasthenia | Beare-Stevenson Syndrome | Patent Foramen Ovale | Swine Influenza | Myelitis | Epidermolytic Palmoplantar Keratoderma | Cardiomyopathy, Hypertrophic | Nephroblastoma | Carcinoma, Merkel Cell | Homocystinuria | Thyroid Dyshormonogenesis | Colitis, Collagenous | WAGR Syndrome | Usher Syndrome Type III | Metatropic Dysplasia | Plasma Cell Dyscrasia | REM Sleep Behavior Disorder | Budd-Chiari Syndrome | Periventricular Nodular Heterotopia | Acne Vulgaris | Cockayne Syndrome | Cabezas Syndrome | NDH Syndrome | Familial Advanced Sleep Phase Syndrome | Enlarged Vestibular Aqueduct | MIRAGE Syndrome | Granular Corneal Dystrophy | Harlequin Ichthyosis | Asthma | X-linked Charcot-Marie-Tooth Disease | Lipid Storage Diseases | Epithelial-myoepithelial Carcinoma | Porencephaly | Marfan Syndrome | Shwachman-Bodian-Diamond Syndrome | Hepatitis D | Kawasaki Disease | Smith-Magenis Syndrome | Trachoma | Dupuytren Disease | Pterygium | Takenouchi-Kosaki Syndrome | Multiple Sclerosis, Relapsing-remitting | Senior-Loken Syndrome | Odonto-onycho-dermal Dysplasia | Bacterial Meningitis | Chondromyxoid Fibroma | Coffin-Lowry Syndrome | Pupil Disorders | Uveitis | Congenital Aniridia | Migraine | Gerstmann-Straussler-Scheinker Syndrome | Familial Mediterranean Fever | Delirium | Neuromuscular Disorders | L-2-Hydroxyglutaric Aciduria | Vitelliform Macular Dystrophy | Facioscapulohumeral Muscular Dystrophy Type 2 | Tatton-Brown-Rahman Syndrome | Myopia | Chorea-acanthocytosis | Glioblastoma Multiforme | Alagille Syndrome | Autosomal Recessive Congenital Ichthyosis | Anorexia Nervosa | Corneal Dystrophies, Hereditary | Glycogen Storage Disease Type 1a | Coloboma | Compartment Syndrome | Hypobetalipoproteinemias | Urolithiasis | Atopy | Non-Langerhans Cell Histiocytosis | Congenital Nephrotic Syndrome | Choriocarcinoma | Ichthyosis Hystrix, Curth-Macklin Type | Arthritis | Chronic Periodontitis | Toxoplasmosis | Kaposiform Hemangioendothelioma | Congenital Stationary Night Blindness | Krabbe Disease | Leprosy | Familial Male-limited Precocious Puberty | Carney-Stratakis Syndrome | LMNA-related Congenital Muscular Dystrophy | Craniolenticulosutural Dysplasia | Tibial Muscular Dystrophy | Oculocutaneous Albinism Type 4 | Liddle Syndrome | Oculocutaneous Albinism Type 1 | Proctitis | Hepatitis E | Schizoaffective Disorder | MELAS Syndrome | Motion Sickness | Histiocytosis | Multiple System Atrophy | Portal Vein Thrombosis | Oculocutaneous Albinism Type 2 | Holoprosencephaly | Lichen Planus | Bruck Syndrome