Disease

Nephrotic Syndrome Type 1

About the Disease
Nephrotic Syndrome, Type 1, also known as finnish congenital nephrosis, is related to nephrotic syndrome, type 2 and focal segmental glomerulosclerosis 1, and has symptoms including edema An important gene associated with Nephrotic Syndrome, Type 1 is NPHS1 (NPHS1 Adhesion Molecule, Nephrin), and among its related pathways/superpathways are Cell junction organization and Primary focal segmental glomerulosclerosis (FSGS). Affiliated tissues include kidney, placenta and brain, and related phenotypes are proteinuria and abnormal renal tubule morphology

Common Targets
CRB2 | NPHS1

疾病靶点研报
Nephrotic Syndrome Type 1

Note: If you'd like to get a target analysis report for Nephrotic Syndrome Type 1, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Nephrotic Syndrome Type 1 at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

MELAS Syndrome | Dyggve-Melchior-Clausen Disease | Schizotypal Personality Disorder | Long QT Syndrome Type 2 | Benign Familial Neonatal Convulsions | Thalassemia, Beta | Osmotic Demyelination Syndrome | Shprintzen-Goldberg Syndrome | Adrenomyeloneuropathy | Obesity | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Congenital Dyserythropoietic Anemia | Infectious Diarrhea | Postpartum Depression | Bronchitis, Chronic | Acne | Transcobalamin Deficiency | Generalized Epilepsy And Paroxysmal Dyskinesia | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Contact Dermatitis | Heterotopic Ossification | Congenital Dyserythropoietic Anemia Type 1 | Atrioventricular Septal Defect | Focal Facial Dermal Dysplasia | Turner's Syndrome | Cryptococcal Meningitis | Neurotoxicity | Diabetes | Niemann-Pick Disease, Type B | Cheilitis | Meesmann Corneal Dystrophy | Spondyloarthritis | Pulmonary Stenosis | Spinal Muscular Atrophy Type 3 | Oculocutaneous Albinism Type 2 | Ectrodactyly | Epidermolytic Hyperkeratosis | Acral Lentiginous Melanoma | Proximal Symphalangism | Coronary Restenosis | Impetigo | Parvovirus B19 Infection | Melanoma, Malignant | Microphthalmia | Hypercholesterolemia | Anosmia, Congenital | Bardet-Biedl Syndrome | Leukodystrophies | Megalencephaly | Muckle-Wells Syndrome | Antisocial Personality Disorder | Fatty Aldehyde Dehydrogenase Deficiency | Medulloblastoma | B-cell Prolymphocytic Leukemia | Schamberg Disease | Lactose Intolerance | Behavioral Variant Of Frontotemporal Dementia | Mesothelioma, Malignant | Epithelioid Hemangioma | Hepatitis E | Autoimmune Polyendocrine Syndrome | Fragile X Syndrome | Wolman Disease | Epidermolysis Bullosa Simplex | Alstrom Syndrome | Schindler Disease | Erythromelalgia | Paracoccidioidomycosis | Rash | Becker Muscular Dystrophy | Scoliosis | Mitochondrial Myopathy | Discoid Lupus Erythematosus | Perivascular Epithelioid Cell Tumor | Albinism | Galactosemia | Malaria, Cerebral | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Myelofibrosis | Bone Marrow Necrosis | Xeroderma Pigmentosum | Eating Disorder | Erythematotelangiectatic Rosacea | TARP Syndrome | Pseudohypoparathyroidism Type 1C | Hepatic Steatosis | NGLY1 Deficiency | Sotos Syndrome | Sporadic Inclusion Body Myositis | Angiosarcoma | Adrenoleukodystrophy, X-linked | Congenital Dyserythropoietic Anemia Type 4 | Hydrops Fetalis | Maternally Inherited Diabetes And Deafness | Gnathodiaphyseal Dysplasia | Optic Neuropathy, Anterior Ischemic | Klippel-Feil Syndrome | Myosin Storage Myopathy | Chorioretinitis | Seizures | Meningioma | Combined Pituitary Hormone Deficiency | Glycogen Storage Disease Type 1a | Optic Neuritis | Familial Pheochromocytoma-paraganglioma | Thrombocythemia, Essential | Myositis, Focal | Progressive External Ophthalmoplegia | Lipid Storage Myopathy | Chronic Enteropathy Associated With SLCO2A1 Gene | Enterocolitis, Necrotizing | Herpes Simplex Dermatitis | Otosclerosis | Progressive Familial Intrahepatic Cholestasis Type 1 | Protein S Deficiency | Congenital Hereditary Endothelial Dystrophy Type I | Azoospermia | Marinesco-Sjogren Syndrome | Rhabdomyosarcoma | Mastitis | Angiosarcoma Of The Breast | Non-Hodgkin Lymphoma | Otitis Media | Papillon-Lefevre Syndrome | Hemorrhagic Disorders | LRBA Deficiency | Epidermolysis Bullosa Simplex, Generalized | Arteriosclerosis | Charcot-Marie-Tooth Disease, Type 1A | Dysthymia | Smoldering Myeloma | Pheochromocytoma | Duchenne Muscular Dystrophy | Dwarfism | Aneurysm, Abdominal Aortic | Leukoencephalopathy, Progressive Multifocal | Cherubism | Eclampsia | Small Lymphocytic Lymphoma | Dermatitis | Hypolipoproteinemia | Acromegaly | Hypermethioninemia | Autism Spectrum Disorders | Waardenburg Syndrome Type 2A | Familial Retinal Arterial Macroaneurysm | Choroiditis | Infantile Spasm | Cholelithiasis | Pouchitis | Erythema Nodosum | Erdheim-Chester Disease | POEMS Syndrome | Syphilis | Hypokalemia | Language Disorders | Autosomal Recessive Spastic Paraplegia Type 35 | Otitis Externa | Spinocerebellar Ataxia Type 23 | Glycogen Storage Disease Type 1b | Priapism | Hemolytic Uremic Syndrome | Hepatitis, Autoimmune | Brachial Plexus Neuropathy | Charcot-Marie-Tooth Disease, Type 2C | Proteus Syndrome | Lipodystrophy | Jalili Syndrome | Hyperparathyroidism-jaw Tumor Syndrome | Frontometaphyseal Dysplasia | Cystitis, Interstitial | Focal Dermal Hypoplasia | Retinal Degeneration | Chediak-Higashi Syndrome | Treacher Collins Syndrome | Agranulocytosis | Trichothiodystrophy | Renal Tubular Dysgenesis | Pityriasis Rubra Pilaris | Gestational Trophoblastic Disease | Restrictive Dermopathy | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Tylosis With Esophageal Cancer | Hemorrhoids | Anemia | Angioedema, Acquired | Pyruvate Decarboxylase Deficiency | Lymphoma Lymphoblastic | Gallstones | Unverricht-Lundborg Syndrome | Peutz-Jeghers Syndrome | Zygomycosis | Nicotine Dependence | Congenital Mirror Movements | Tendinopathy | Amenorrhea | Tangier Disease | Cystinosis | Heart Failure | Cholangitis | Hemosiderosis | Beta-Propeller Protein-associated Neurodegeneration | Cryptorchidism | Sturge-Weber Syndrome | Camptocormia | Low Tension Glaucoma | Menetrier Disease | Plasmacytoma | Menkes Disease | Ocular Hypertension | Primary Torsion Dystonia | Molybdenum Cofactor Deficiency | Paternal Uniparental Disomy Of Chromosome 14 | Shwachman-Bodian-Diamond Syndrome | Cancer, Brain | Genee-Wiedemann Syndrome | Silver-Russell Syndrome | Aspartylglycosaminuria | Mountain Sickness | Dupuytren Disease | Methylmalonic Acidemia | Glioma | Lupus Erythematosus | Genitopatellar Syndrome | Arthritis, Reactive | Hemangioma | Pelvic Inflammatory Disease | Chromosome 9q34.3 Deletion Syndrome | McCune-Albright Syndrome | Osteochondroma | Seizures-scoliosis-macrocephaly Syndrome | Infertility, Male | Rubeosis Iridis | Oligoastrocytoma | Atherosclerosis | GM2-gangliosidosis AB Variant | Neurofibromatosis-Noonan Syndrome | McKusick Type Metaphyseal Chondrodysplasia | Sarcoma, Alveolar Soft Part | Isobutyryl-CoA Dehydrogenase Deficiency | Hypocalcemia | Hyperekplexia | Hydrocephalus, Normal Pressure | Deafness, Dystonia, And Cerebral Hypomyelination | Liver Failure | X-linked Charcot-Marie-Tooth Disease | Diabetes Mellitus, Transient Neonatal | Cerebral Cavernous Malformations | Lymphoproliferative Disease, X-linked | Papillorenal Syndrome | Hydrolethalus Syndrome | Ischemia | Paronychia | Cellulitis | Lipoma | Pachyonychia Congenita | Fanconi Syndrome | Bethlem Myopathy | Bronchiolitis | Kashin-Beck Disease | Campomelic Dysplasia | Klinefelter Syndrome | Thanatophoric Dysplasia Type 1 | Dubin-Johnson Syndrome | Chorea | Anterior Segment Dysgenesis | Familial Exudative Vitreoretinopathy | Common Variable Immunodeficiency | Waardenburg Syndrome | Hypotension, Orthostatic | Noonan Syndrome | Pemphigus Vulgaris | Acromesomelic Dysplasia | Hypermetropia | Pulmonary Vein Stenosis | Splenomegaly | Sleep Apnea | 3C Syndrome | Charcot-Marie-Tooth Disease, Type 2A | Pierson Syndrome | Spinocerebellar Ataxia | Oculocutaneous Albinism Type 4 | Neuropathy | Tuberculosis | HANAC Syndrome | Cancer, Colon | Meningioma, Benign | Primary Aldosteronism | Coma | Sleep Apnea, Obstructive | Diamond-Blackfan Anemia | Cervical Dystonia | Fibronectin Glomerulopathy | Thrombosis | Glioblastoma Multiforme | Dysfibrinogenemia | Gangliosidosis, GM1 | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Chondrodysplasia Punctata | Exostoses | Hypotrichosis | Chylothorax, Congenital | Anthrax | Cold Agglutinin Disease | Niemann-Pick Disease, Type C | Absence Epilepsy | Primary Erythromelalgia | Polyomavirus Nephropathy | CHOPS Syndrome | Hemolytic Uremic Syndrome, Atypical | Charcot-Marie-Tooth Disease Axonal Type 2N | Crohn's Disease | Babesiosis | Guttate Psoriasis | Spina Bifida | Lichen Planus | Cartilage Disorders | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Trismus-pseudocamptodactyly Syndrome | Porphyria Cutanea Tarda | Echinococcosis | Metatropic Dysplasia | Senior-Loken Syndrome | Feingold Syndrome | Cervicitis | Urticaria | Acute Myeloid Leukemia | Hartsfield Syndrome | WAGR Syndrome | Glycogen Storage Disease Type 4 | Branchiootorenal Syndrome | Carcinoma, Signet Ring Cell | Asperger Syndrome | Epicondylitis | Familial Hyperaldosteronism | Filariasis | Congenital Heart Block | Lissencephaly 2 | MIRAGE Syndrome | Preaxial Polydactyly | Blau Syndrome | Tinea | Carcinoid Syndrome | Optic Neuropathy | Trichomegaly | Cramp Fasciculation Syndrome | Dyskeratosis Congenita | Niemann-Pick Disease | Mixed Connective Tissue Disease | Netherton Syndrome | Kleine-Levin Syndrome | DOCK8 Immunodeficiency Syndrome | Vascular Cognitive Impairment | Acute Lung Injury | Takayasu's Arteritis | Parkinsonism | Myelitis | Myoclonic Epilepsy With Ragged Red Fibers | Mucolipidosis Type II | Rhinitis | Hidradenitis | Hartnup Disease | Obsessive-compulsive Disorder | Congenital Primary Aphakia | Knobloch Syndrome | Seborrheic Dermatitis | Familial Male-limited Precocious Puberty | Hepatitis, Alcoholic | Hemophilia | Calcium Pyrophosphate Deposition Disease | Retinal Detachment | Lymphangiomatosis | Arts Syndrome | Intestinal Pseudo-obstruction | Juvenile Myoclonic Epilepsy | Schuurs-Hoeijmakers Syndrome | Jawad Syndrome | Muscular Dystrophy | Myoclonus-dystonia Syndrome | Infertility | Early Infantile Epileptic Encephalopathy 13 | Glycogen Storage Disease Type 9 | Double Outlet Right Ventricle | Congenital Lipoid Adrenal Hyperplasia | Congenital Fiber-type Disproportion Myopathy | Pneumothorax | Sandhoff Disease | Dysferlinopathy | Schizencephaly | Carcinoma, Small Cell | Chromosome 5q Deletion Syndrome | Neurocutaneous Melanocytosis | Wieacker-Wolff Syndrome | Photosensitivity | Hepatitis B, Chronic | Nager Acrofacial Dysostosis | Peripheral T-cell Lymphoma | Apert Syndrome | Hyperthermia, Malignant