Oculocutaneous Albinism Type 2

About the Disease
Albinism, Oculocutaneous, Type Ii, also known as oca2, is related to skin/hair/eye pigmentation, variation in, 1 and acute contagious conjunctivitis. An important gene associated with Albinism, Oculocutaneous, Type Ii is OCA2 (OCA2 Melanosomal Transmembrane Protein), and among its related pathways/superpathways are GPR143 in melanocytes and retinal pigment epithelium cells and Prader-Willi and Angelman syndrome. Affiliated tissues include skin, eye and retina, and related phenotypes are nystagmus and abnormality of retinal pigmentation

Common Targets
TYR | OCA2 | SLC45A2

Note: If you'd like to get a target analysis report for Oculocutaneous Albinism Type 2, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Oculocutaneous Albinism Type 2 at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Arts Syndrome | Spinocerebellar Ataxia Type 40 | Postaxial Polydactyly | Cardiomyopathy, Dilated, 1L | Spinocerebellar Ataxia Type 5 | Juvenile Myoclonic Epilepsy | Congenital Fiber-type Disproportion Myopathy | Adenomatoid Tumor | Exfoliative Dermatitis | Turner's Syndrome | Androgen Insensitivity | Renpenning Syndrome | Asthma, Nocturnal | Treacher Collins Syndrome | Kidney Stones | Focal Facial Dermal Dysplasia | Mumps | Primary Hyperoxaluria | Myeloid Leukemia | Pemphigus Vulgaris | Cerebral Cavernous Malformations | Omenn Syndrome | Oguchi Disease-2 | Diabetic Neuropathy | Takayasu's Arteritis | Sarcomatoid Carcinoma Of The Lung | Leukocyte Adhesion Deficiency | Hypercalciuria | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Osteogenesis Imperfecta | Thymoma, Malignant | Blue Rubber Bleb Nevus Syndrome | Cataplexy | Delirium | Oculocutaneous Albinism | Thyroid Dysgenesis | Neuroendocrine Cancer | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Cocaine-Related Disorders | Acute Chest Syndrome | Rhabdomyosarcoma, Alveolar | Polyneuropathy | Metabolic Syndrome | Retinal Degeneration | Familial Exudative Vitreoretinopathy | Insulin Resistance | Encephalitis | Frontometaphyseal Dysplasia | Sjogren Syndrome | Colorectal Adenoma | Fanconi Anemia | Strabismus | Bare Lymphocyte Syndrome | Impulse Control Disorder | Sickle Cell Disease | Delayed Sleep Phase Syndrome | Agammaglobulinemia | Optic Neuropathy | Kleine-Levin Syndrome | Bacterial Meningitis | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Chorioretinitis | Blepharitis | Methemoglobinemia | Granular Corneal Dystrophy Type 1 | Antisocial Personality Disorder | Nephrotic Syndrome Type 1 | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Hyperinsulinism-hyperammonemia Syndrome | Pulverulent Zonular Cataract | Chronic Enteropathy Associated With SLCO2A1 Gene | Retinitis Pigmentosa | Congenital Heart Block | Glycogen Storage Disease Type 0 | Hyperkeratosis | Lesch-Nyhan Syndrome | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Chronic Thromboembolic Pulmonary Hypertension | Spinocerebellar Ataxia Type 14 | Hydrolethalus Syndrome | T-cell Prolymphocytic Leukemia | Duodenal Atresia | Glycogen Storage Disease Type 4 | Withdrawal Syndrome | Histoplasmosis | Esotropia | Diarrhea | Motor Neuron Diseases | Focal Dermal Hypoplasia | Blastomycosis | Hepatoblastoma | Glycogen Storage Disease | Achromatopsia | Congenital Lipoid Adrenal Hyperplasia | Spinocerebellar Ataxia Type 27 | Primary Lateral Sclerosis | Pulmonary Capillary Hemangiomatosis | Esophageal Adenocarcinoma | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Carotid Artery Disease | Oligoastrocytoma | Hyperbilirubinemia | Gastroschisis | Williams Syndrome | Spinocerebellar Ataxia Type 10 | Proximal Symphalangism | Goiter, Nodular | Cranioectodermal Dysplasia | Hereditary Pyropoikilocytosis | Antley-Bixler Syndrome | Pneumothorax | Chordoma | Cholangitis | Eccrine Porocarcinoma | Kabuki Syndrome 2 | Spondylocostal Dysostosis | Transient Bullous Dermolysis Of The Newborn | Neuroblastoma | Hypercholesterolemia, Familial | Epithelial-myoepithelial Carcinoma | Fetal Alcohol Syndrome | Spinocerebellar Ataxia Type 20 | Fukuyama Congenital Muscular Dystrophy | Osteopetrosis | Guillain-Barre Syndrome | Bainbridge-Ropers Syndrome | Fascioliasis | Von Willebrand Disease | Alexander Disease | Acne | Silver-Russell Syndrome | Coffin-Lowry Syndrome | Hereditary Coproporphyria | Cryoglobulinemia | Tinea Versicolor | Pelvic Inflammatory Disease | Facioscapulohumeral Muscular Dystrophy | Eiken Syndrome | Takenouchi-Kosaki Syndrome | Kohlschutter-Tonz Syndrome | Cenani-Lenz Syndactyly Syndrome | Diverticulitis | Mitochondrial DNA Depletion Syndrome | Congenital Disorders Of Glycosylation Type II | Neurogenic Bladder | Fibrosis | Cyst | Osteitis | Imerslund-Grasbeck Syndrome | Cystinosis | Glycogen Storage Disease Type 1 | Palmoplantar Keratoderma | Bronchiolitis | Autonomic Neuropathy | Hepatitis, Chronic | Chronic Granulomatous Disease, X-linked | Polycythemia | Pouchitis | Spinocerebellar Ataxia Type 8 | Hypothyroidism | Swine Influenza | Spondylometaphyseal Dysplasia | Acromesomelic Dysplasia | Lattice Corneal Dystrophy | Whipple's Disease | Hyperbilirubinemia, Neonatal | Portal Vein Thrombosis | Neurofibroma | Primary Hyperoxaluria Type 1 | Smith-Lemli-Opitz Syndrome | Muscle Wasting | Alcoholism | Situs Inversus | Proteasome-associated Autoinflammatory Syndrome 2 | Hereditary Spastic Paraplegia | Schuurs-Hoeijmakers Syndrome | Geleophysic Dysplasia | Zollinger-Ellison Syndrome | Early Infantile Epileptic Encephalopathy 13 | Thyroid Dyshormonogenesis | Spinocerebellar Ataxia Type 1 | Spinal Muscular Atrophy Type 3 | Blau Syndrome | Japanese Encephalitis | Pyloric Stenosis, Infantile Hypertrophic | Hypermethioninemia | Cockayne Syndrome | Klippel-Feil Syndrome | Craniometaphyseal Dysplasia | Osteochondrosis | Schnitzler Syndrome | IgA Deficiency | Periventricular Nodular Heterotopia | Metachondromatosis | Congenital Adrenal Hyperplasia | Primary Erythromelalgia | Arthritis, Psoriatic | Gyrate Atrophy Of The Choroid And Retina | Chromosome 5q Deletion Syndrome | Multiple Hamartoma Syndrome | Muir-Torre Syndrome | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Antiphospholipid Syndrome | Hyperferritinemia-cataract Syndrome | Mucolipidosis Type II | Urticaria | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Mycosis Fungoides | Lymphedema-distichiasis Syndrome | Neurocutaneous Syndromes | Actinomycetoma | Hypokalemic Periodic Paralysis | Acute Anterior Uveitis | Myoclonic Atonic Epilepsy | Charcot-Marie-Tooth Disease, Type 2 | Alzheimer Disease, Late Onset | Schistosomiasis | Pyelonephritis | Language Disorders | Thromboembolism | Gastroenteritis, Eosinophilic | Hypogammaglobulinemia | Cherubism | AIDS Dementia Complex | Hypercalcemia | Osteosarcoma | Myelomeningocele | Glycogen Storage Disease Type 1b | Wagner Disease | Peyronie's Disease | Spinocerebellar Ataxia Type 6 | Bullous Pemphigoid | Craniopharyngioma | Ophthalmia, Sympathetic | DNA Ligase IV Deficiency | Schnyder Crystalline Corneal Dystrophy | Sarcoma, Ewing | Optic Neuritis | Usher Syndrome Type IIC | Hyperekplexia | Benign Familial Neonatal Convulsions | Megalencephaly | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Isovaleric Acidemia | Knobloch Syndrome | Pyoderma Gangrenosum | Guttate Psoriasis | Essential Fructosuria | Carey-Fineman-Ziter Syndrome | Exotropia | Occipital Neuralgia | Prader-Willi Syndrome | Oligoasthenoteratozoospermia | Pituitary Stalk Interruption Syndrome | Palsy, Cerebral | Carcinoid Syndrome | Cushing Syndrome | Desmosterolosis | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Arthritis, Gouty | Transcobalamin Deficiency | Fundus Albipunctatus | Wiedemann-Steiner Syndrome | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Pyruvate Carboxylase Deficiency Disease | Erdheim-Chester Disease | Glucagonoma | Sclerocornea | Basal Ganglia Cerebrovascular Disease | Kearns-Sayre Syndrome | Shprintzen-Goldberg Syndrome | Atrial Septal Defect | Poretti-Boltshauser Syndrome | Speech Disorders | Usher Syndrome | Motion Sickness | Liddle Syndrome | Hydronephrosis | Molybdenum Cofactor Deficiency | Craniofrontonasal Syndrome | Insulinoma | Mucolipidosis Type IV | Liver Diseases | Frank-ter Haar Syndrome | Encephalopathy, Ethylmalonic | Hypertension, Renovascular | Lyme Disease | Carpal Tunnel Syndrome | Angioedema | Chromosome 17q21.31 Deletion Syndrome | Angelman Syndrome | Osteoglophonic Dysplasia | Subacute Sclerosing Panencephalitis | Cole-Carpenter Syndrome | Sezary Syndrome | Pulmonary Veno-occlusive Disease | Leukemia-lymphoma, Adult T-cell | Angioedema, Acquired | Vitelliform Macular Dystrophy | Carbamoyl Phosphate Synthetase I Deficiency | Cholestasis, Intrahepatic | LMNA-related Congenital Muscular Dystrophy | Muscular Dystrophy | Polycythemia Vera | Stevens-Johnson Syndrome | Glycogen Storage Disease Type 6 | Nijmegen Breakage Syndrome | Colitis, Collagenous | Agnathia-Otocephaly Complex | Combined Pituitary Hormone Deficiency | Holoprosencephaly | Protein S Deficiency | Zygomycosis | Ataxia-ocular Apraxia 2 | Meconium Ileus | Loeys-Dietz Syndrome | Fowler's Syndrome | Hypertension, Pulmonary | Mitochondrial Disease | Overactive Bladder | Malaria, Cerebral | Episodic Ataxia Type 1 | Optic Neuropathy, Anterior Ischemic | Tylosis With Esophageal Cancer | Familial Dysautonomia | Cleidocranial Dysplasia | Centronuclear Myopathy | Lewy Body Dementia | X-linked Acrogigantism | Colitis, Microscopic | Acromicric Dysplasia | Hyperparathyroidism | Acquired Partial Lipodystrophy | McCune-Albright Syndrome | Vaginitis | Pleural Tuberculosis | Gout | Pure Autonomic Failure | McLeod Syndrome | Thrombotic Microangiopathy | Follicular Dendritic Cell Sarcoma | Hyper IgE Syndrome | Congenital Hereditary Endothelial Dystrophy Type II | Cerebellar Ataxia, Cayman Type | Hartsfield Syndrome | Nail Disorder, Nonsyndromic Congenital | Pre-eclampsia | GNE Myopathy | Conduct Disorder | Avellino Corneal Dystrophy | Neonatal Progeroid Syndrome | Stroke, Hemorrhagic | Cabezas Syndrome | Vertigo | Hyperphenylalaninemia | Hereditary Neuropathy With Liability To Pressure Palsies | Myelitis | Metabolic Diseases | Acute Lung Injury | Hyperparathyroidism-jaw Tumor Syndrome | Infantile Nephropathic Cystinosis | Lactose Intolerance | Cholelithiasis | Inflammatory Linear Verrucous Epidermal Nevus | Presbycusis | Hypermetropia | Mitochondrial Encephalomyopathy | Pneumonia, Mycoplasma | Cholesteryl Ester Storage Disease | Spinocerebellar Ataxia Type 2 | Meningitis | Epidermodysplasia Verruciformis | Noonan Syndrome-like Disorder With Loose Anagen Hair | Myoclonus | Large Granular Lymphocytic Leukemia | Paraplegia | Charcot-Marie-Tooth Disease Type 2T | POEMS Syndrome | Familial Retinal Arterial Macroaneurysm | Cryptorchidism | Congenital Dyserythropoietic Anemia Type 4 | Colitis, Lymphocytic | Sialoadenitis | Ophthalmoplegia | Pilomatrix Carcinoma | Major Depression | SAPHO Syndrome | Schizoaffective Disorder | Micropenis | Primary Progressive Aphasia | Camptocormia | Orthostatic Intolerance | Walker-Warburg Syndrome | Adenosine Deaminase Deficiency | Down Syndrome | Learning Disability | Holt-Oram Syndrome | Acute Coronary Syndrome | HELLP Syndrome | Craniofacial Dysostosis