Disease

Oculocutaneous Albinism Type 2

About the Disease
Albinism, Oculocutaneous, Type Ii, also known as oca2, is related to skin/hair/eye pigmentation, variation in, 1 and acute contagious conjunctivitis. An important gene associated with Albinism, Oculocutaneous, Type Ii is OCA2 (OCA2 Melanosomal Transmembrane Protein), and among its related pathways/superpathways are GPR143 in melanocytes and retinal pigment epithelium cells and Prader-Willi and Angelman syndrome. Affiliated tissues include skin, eye and retina, and related phenotypes are nystagmus and abnormality of retinal pigmentation

Common Targets
TYR | OCA2 | SLC45A2

疾病靶点研报
Oculocutaneous Albinism Type 2

Note: If you'd like to get a target analysis report for Oculocutaneous Albinism Type 2, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Oculocutaneous Albinism Type 2 at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Nephropathy | Chloridorrhea, Congenital | Basan Syndrome | Renal Oncocytoma | Urofacial Syndrome | Absence Epilepsy | Long QT Syndrome Type 2 | Vitamin B12 Deficiency | Hypoplastic Left Heart Syndrome | Chorea-acanthocytosis | Discoid Lupus Erythematosus | Malonyl-CoA Decarboxylase Deficiency | Glutaric Aciduria Type 3 | Eclampsia | Acute Lung Injury | Stuve-Wiedemann Syndrome | Beckwith-Wiedemann Syndrome | Open-angle Glaucoma | Lymphoma, Follicular | Eosinophilia | Anemia | Stromal Corneal Dystrophy | Gliosarcoma | Early Infantile Epileptic Encephalopathy 13 | Acute Generalized Exanthematous Pustulosis | Cerebellofaciodental Syndrome | Histiocytosis | Anosmia, Congenital | Cholesteryl Ester Storage Disease | Jacobsen Syndrome | Spinocerebellar Ataxia Type 20 | Diastrophic Dysplasia | Wolfram Syndrome 2 | Familial Isolated Hyperparathyroidism | DICER1 Syndrome | Aneurysm, Thoracic Aortic | Carbohydrate Metabolism Disorders | Myositis | Agnathia-Otocephaly Complex | Bulimia Nervosa | Fibrosis | Macular Corneal Dystrophy Type 1 | Glaucoma | Myasthenia | Infantile Spasm | Disseminated Intravascular Coagulation | Metaphyseal Chondrodysplasia, Schmid Type | Uterine Leiomyoma | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Desbuquois Syndrome | Stickler Syndrome | Asperger Syndrome | Epidermal Nevus Syndrome | Cardiofaciocutaneous Syndrome | L-2-Hydroxyglutaric Aciduria | Acromegaly | Leukocyte Adhesion Deficiency Type 1 | Varicocele | Spinocerebellar Ataxia Type 23 | Acute Lymphocytic Leukemia | Cataplexy | Intestinal Pseudo-obstruction | Optic Neuropathy, Anterior Ischemic | Keratitis-ichthyosis-deafness Syndrome | Tinea Versicolor | Sleep Apnea, Central | Charcot-Marie-Tooth Disease Type 4E | Oculopharyngeal Muscular Dystrophy | Focal Cortical Dysplasia Type 2 | Hodgkin Lymphoma | Creatine Deficiency Syndrome Due To AGAT Deficiency | Vascular Cognitive Impairment | Priapism | Epidermodysplasia Verruciformis | Chondrodysplasia Punctata | Bethlem Myopathy | Schwannoma | Incontinentia Pigmenti | Distal Spinal Muscular Atrophy | Li-Fraumeni Syndrome | Niemann-Pick Disease, Type C | Potocki-Shaffer Syndrome | Chronic Myeloid Leukemia | Cardiomyopathy, Hypertrophic | Carcinoma, Small Cell | Lipid Storage Diseases | Anuria | Irritable Bowel Syndrome | Fraser Syndrome | Familial Thoracic Aortic Aneurysm | Dystonia Musculorum Deformans | DEND Syndrome | Leber Hereditary Optic Neuropathy | Non-bullous Congenital Ichthyosiform Erythroderma | Amebiasis | Chondrosarcoma | Hepatitis, Alcoholic | Nemaline Myopathy 8 | Esthesioneuroblastoma | Neuromuscular Disorders | Bartter Syndrome | Oral Lichen Planus | Postpartum Depression | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Hyperparathyroidism, Secondary | Glutaric Aciduria Type 2 | Spasticity | Distal Myopathy | Progressive Familial Intrahepatic Cholestasis Type 3 | CEDNIK Syndrome | Thromboembolism | Cystinuria | Pemphigus | Vasculitis | Cousin Syndrome | Hereditary Inclusion Body Myopathy | Beare-Stevenson Syndrome | Tyrosinemia Type 1 | Sporadic Hemiplegic Migraine | Enhanced S-cone Syndrome | Carcinoma, Transitional Cell | Cockayne Syndrome | Supravalvular Aortic Stenosis | Fibrosarcoma | Sensory Neuropathy | Glanzmann Thrombasthenia | Frank-ter Haar Syndrome | Hereditary Spastic Paraplegia | Hyperinsulinism-hyperammonemia Syndrome | Congenital Adrenal Hyperplasia | Leukoencephalopathy, Progressive Multifocal | Periodic Limb Movement Disorder | Norrie Disease | Goldenhar Syndrome | Syphilis | Scleroderma, Diffuse | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Glycogen Storage Disease Type 0 | Myocarditis | Hyperkalemic Periodic Paralysis | Lymphedema-distichiasis Syndrome | Congenital Primary Aphakia | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Eating Disorder | Gingivitis | Angiomyolipoma | Acral Lentiginous Melanoma | Jaundice, Obstructive | Carpal Tunnel Syndrome | Polycythemia Vera | Cutaneous Angiosarcoma | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Bronchiolitis | Stargardt Disease | Pure Red Cell Aplasia | Osteogenesis Imperfecta Type VI | Niemann-Pick Disease, Type B | Hairy Cell Leukemia | GNE Myopathy | Spinal Cord Diseases | Alpha-thalassemia Myelodysplasia Syndrome | Renal-hepatic-pancreatic Dysplasia | Fascioliasis | Schistosomiasis | Meleda Disease | Spinocerebellar Ataxia Type 10 | Angelman Syndrome | Uremia | Retinal Coloboma | Cryptorchidism | Multiple Sclerosis | Wolfram Syndrome | Double Outlet Right Ventricle | Lafora Disease | Acanthosis Nigricans | Oligospermia | Neutrophilia | Fatty Aldehyde Dehydrogenase Deficiency | Chronic Myelomonocytic Leukemia | Major Depression | Creutzfeldt-Jakob Disease | Congenital Nephrotic Syndrome | Wagner Disease | Pleurisy | Splenomegaly | Superficial Spreading Melanoma | Porphyria, Variegate | Intermittent Claudication | Diabetic Encephalopathy | Strabismus | Mountain Sickness | Leukodystrophies | Adenoma, Pleomorphic | Familial Hypobetalipoproteinemia | Congenital Disorders Of Glycosylation Type II | Anti-NMDA Receptor Encephalitis | Vitamin K Deficiency | Non-Langerhans Cell Histiocytosis | Keratitis | Toxoplasmosis | Demyelinating Diseases | Pemphigus Vulgaris | Ganglioneuroma | Pulmonary Stenosis | Autism Spectrum Disorders | Blastomycosis | Osteonecrosis | Chudley-McCullough Syndrome | Pleomorphic Xanthoastrocytoma | Azoospermia | Temtamy Preaxial Brachydactyly Syndrome | Trachoma | Tangier Disease | Erythema Multiforme | Hypocalcemia | Pterygium | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Lymphoma | Proteus Syndrome | Corneal Dystrophy And Perceptive Deafness | Sarcoma, Alveolar Soft Part | Succinic Semialdehyde Dehydrogenase Deficiency | Hemochromatosis Type 1 | Ectrodactyly | Cervicitis | Kaposiform Hemangioendothelioma | Epilepsy Of Infancy With Migrating Focal Seizures | Sandhoff Disease | Mannosidase Deficiency Diseases | Exostoses | Ganglioglioma | Language Disorders | Glutaric Aciduria Type 1 | Intestinal Obstruction | Early Infantile Epileptic Encephalopathy 28 | Myelodysplasia | Ichthyosis Bullosa Of Siemens | Chronic Periodontitis | Hyperuricemia | Congenital Nystagmus | Panuveitis | Coronary Restenosis | Woodhouse-Sakati Syndrome | Thrombasthenia | Temporal Lobe Epilepsy | Gerodermia Osteodysplastica | Familial Episodic Pain Syndrome | Salla Disease | Tibial Muscular Dystrophy | Relapsing Polychondritis | Long QT Syndrome Type 3 | Rash | Glutathione Synthetase Deficiency | Restless Legs Syndrome | Kohlschutter-Tonz Syndrome | Bone Giant Cell Tumor | Anthrax | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Hypogonadism | Glomerulonephritis, Membranous | Gastroenteritis | Alopecia | Glioblastoma Multiforme | Androgenic Alopecia | Greenberg Dysplasia | Neuropathy | Swine Influenza | Kearns-Sayre Syndrome | Familial Hemiplegic Migraine | Ureteropelvic Junction Obstruction | Corticobasal Syndrome | Warsaw Breakage Syndrome | Myopathy | Hypertension | Dysferlinopathy | Urea Cycle Disorder | Wolcott-Rallison Syndrome | Joubert Syndrome 2 | Congenital Stromal Corneal Dystrophy | Common Cold | Autosomal Recessive Bestrophinopathy | Giant Cell Arteritis | Alopecia Totalis | Vogt-Koyanagi-Harada Syndrome | Creatine Deficiency Syndrome | B-cell Prolymphocytic Leukemia | Hyperferritinemia-cataract Syndrome | Mucormycosis | Leukoplakia | Dysgerminoma | Duodenal Atresia | Corneal Ulcer | Nutrition Disorders | Sarcoma, Ewing | Lyme Disease | Melanoma, Uveal | Blue Nevus | Persistent Mullerian Duct Syndrome | Pulmonary Alveolar Microlithiasis | Extramammary Paget's Disease | Multicystic Renal Dysplasia | Osteochondroma | Triple A Syndrome | Cutaneous T-cell Lymphoma | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Trismus-pseudocamptodactyly Syndrome | Cryptosporidiosis | Retinal Degeneration | Non-small Cell Lung Cancer | Chondroma | Sorsby Fundus Dystrophy | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Congenital Mirror Movements | Pyruvate Carboxylase Deficiency Disease | Diabetes | Angioedema | Prader-Willi Syndrome | Charcot-Marie-Tooth Disease | Cholangiocarcinoma | Pleural Tuberculosis | Mucolipidosis | Esotropia | Aldosteronism | Centronuclear Myopathy | Sensorineural Hearing Loss | Borjeson-Forssman-Lehmann Syndrome | Tyrosinemia Type 2 | Autoimmune Polyendocrine Syndrome | 3-hydroxy-3-methylglutaric Aciduria | Leber Congenital Amaurosis | Keratoconus | Glycogen Storage Disease | Triphalangeal Thumb-polysyndactyly Syndrome | Gallstones | Coenzyme Q10 Deficiency | Cluster Headache | Pancytopenia | Pemphigus Foliaceus | Pneumonia, Mycoplasma | Hyperglycemia | Krabbe Disease | Brooke-Spiegler Syndrome | Autosomal Recessive Spastic Paraplegia Type 35 | Focal Dermal Hypoplasia | Hypertensive Retinopathy | Cancer, Prostate | Nemaline Myopathy | Waardenburg Syndrome Type 4 | Hereditary Sensory And Autonomic Neuropathy | GAPO Syndrome | Spinal Muscular Atrophy | Melanoma, Malignant | Anorexia Nervosa | Toxic Epidermal Necrolysis | Cancer, Colon | Tyrosine Hydroxylase Deficiency | Tuberculous Meningitis | Meconium Ileus | Hydronephrosis | Tyrosinemia | Hypohidrotic Ectodermal Dysplasia, X-linked | Leukoplakia, Oral | Spondyloperipheral Dysplasia | Acute Tubular Necrosis | Pseudohermaphroditism | Diffuse Mesangial Sclerosis | Thrombophlebitis | NDH Syndrome | Rosacea | Spinal And Bulbar Muscular Atrophy | Episodic Ataxia Type 1 | Noonan Syndrome-like Disorder With Loose Anagen Hair | Lymphoma, Mantle Cell | Thyroid Dysgenesis | Cardiospondylocarpofacial Syndrome | Progressive Encephalopathy-optic Atrophy Syndrome | Leiomyoma | Primary Biliary Cholangitis | Meningeal Melanocytoma | Metabolic Diseases | Cataract | Arthritis, Psoriatic | Pulmonary Vein Stenosis | Meier-Gorlin Syndrome | Mucolipidosis Type IV | Hyperphenylalaninemia | Acromicric Dysplasia | Myelitis, Transverse | Vici Syndrome | Arrhythmogenic Right Ventricular Cardiomyopathy | Usher Syndrome Type II | Pemphigoid | Paraganglioma, Carotid Body | Acute Motor Axonal Neuropathy | Hypoglycemia | Angioedema, Hereditary | Spinocerebellar Ataxia Type 8 | Optic Neuritis | Progressive Familial Intrahepatic Cholestasis Type 2 | Tularemia