Disease

Mitochondrial Encephalomyopathy

About the Disease
Mitochondrial Encephalomyopathy, also known as mitochondrial encephalomyopathies, is related to mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes and combined oxidative phosphorylation deficiency 6. An important gene associated with Mitochondrial Encephalomyopathy is MT-CYB (Mitochondrially Encoded Cytochrome B), and among its related pathways/superpathways are Metabolism and "Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.". The drugs 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, brain and occipital lobe.

Common Targets
TMEM70 | NSUN3 | SLC25A42 | DNM1L | SLIRP | ATP6 | ATP8 | COX11 | LIG3 | FASTKD2 | TYMP | MRPS25

疾病靶点研报
Mitochondrial Encephalomyopathy

Note: If you'd like to get a target analysis report for Mitochondrial Encephalomyopathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Mitochondrial Encephalomyopathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Osteogenesis Imperfecta Type I | Hennekam Lymphangiectasia-lymphedema Syndrome | Granular Corneal Dystrophy | Erdheim-Chester Disease | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Heterotopic Ossification | Multifocal Motor Neuropathy | Charcot-Marie-Tooth Disease Type 2T | Cancer, Kidney | Methylmalonic Acidemia | Glycogen Storage Disease Type 0 | Tic Disorder | Sarcomatoid Carcinoma Of The Lung | Transthyretin-related Amyloidosis | Basal Cell Nevus Syndrome | MELAS Syndrome | Diffuse Mesangial Sclerosis | Rothmund-Thomson Syndrome | Epithelial-myoepithelial Carcinoma | Corneal Dystrophy And Perceptive Deafness | Esophageal Motility Disorders | Angiomyolipoma | Nicotine Dependence | Irritable Bowel Syndrome | Congenital Hypofibrinogenemia | Incontinentia Pigmenti | Fraser Syndrome | T-cell Lymphoma, Subcutaneous Panniculitis-like | Polycythemia Vera | Keratoconjunctivitis | Lymphedema | Spinocerebellar Ataxia Type 31 | Spinocerebellar Ataxia Type 17 | Atrioventricular Septal Defect | Axenfeld-Rieger Syndrome | Keratopathy | Familial Exudative Vitreoretinopathy | Infantile Liver Failure Syndrome 1 | Histoplasmosis | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Diabetes Mellitus, Transient Neonatal | Thin Basement Membrane Disease | Anxiety Disorders | Bulimia Nervosa | Spinocerebellar Ataxia Type 5 | Blood Protein Disorders | Homocystinuria | Atelosteogenesis Type 2 | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Arthrogryposis | Erythropoietic Protoporphyria | Chondrodysplasia Punctata 1, X-linked Recessive | Kabuki Syndrome 2 | Intestinal Obstruction | Spondyloepiphyseal Dysplasia Tarda, X-linked | Bainbridge-Ropers Syndrome | Lymphoma Lymphoblastic | Amenorrhea | Acromicric Dysplasia | Carney-Stratakis Syndrome | Intracranial Hypertension | Genitopatellar Syndrome | Congenital Primary Aphakia | Treacher Collins Syndrome | Graves Disease | Hemochromatosis Type 2 | Platelet Disorders | Chronic Enteropathy Associated With SLCO2A1 Gene | Carney Triad | Myelodysplasia | Colitis, Collagenous | Dwarfism | Sponastrime Dysplasia | Aceruloplasminemia | Poikiloderma With Neutropenia | Neutrophilia | Localized Scleroderma | Malnutrition | Renal Hypouricemia | Takayasu's Arteritis | Cluster Headache | Cholestasis, Intrahepatic | Cholangitis | Congenital Afibrinogenemia | Non-Hodgkin Lymphoma | Salla Disease | Porphyria | Lymphoma, Mantle Cell | Triple A Syndrome | Angiodysplasia | Pyruvate Decarboxylase Deficiency | Asperger Syndrome | Ehlers-Danlos Syndrome | Lymphoproliferative Disorders | Arthritis, Psoriatic | Intracerebral Hemorrhage | Hypermetropia | Oligoasthenoteratozoospermia | Pantothenate Kinase-associated Neurodegeneration | Leigh Syndrome | Filariasis | Retinal Detachment | Extramammary Paget's Disease | Acute Lung Injury | Hypercalciuria | Ollier Disease | Autoimmune Hemolytic Anemia | Common Variable Immunodeficiency | Charcot-Marie-Tooth Disease | Fibrillation, Atrial | Arteriosclerosis | Dubin-Johnson Syndrome | Osteitis | Leukoplakia | Goldenhar Syndrome | X-linked Sideroblastic Anemia | Hemolytic Uremic Syndrome | Shwachman-Bodian-Diamond Syndrome | Congenital Hemolytic Anemia | Epidermolysis Bullosa Simplex, Generalized | Interstitial Lung Diseases | Hypertrophy | Parkinsonism | Ectrodactyly | Hyperacusis | Holoprosencephaly | Lassa Fever | Non-bullous Congenital Ichthyosiform Erythroderma | Congenital Dyserythropoietic Anemia | Leukocyte Adhesion Deficiency Type 1 | Rolandic Epilepsy | Glutaric Aciduria Type 2 | Lactose Intolerance | Erectile Dysfunction | Raynaud Phenomenon | Choriocarcinoma | Pelvic Inflammatory Disease | Cutaneous T-cell Lymphoma | Trichomegaly | Hypolipoproteinemia | Campomelic Dysplasia | Japanese Encephalitis | Adrenal Insufficiency | Histiocytic Sarcoma | Charcot-Marie-Tooth Disease Type 2E | Migraine | Congenital Poikiloderma | Veno-occlusive Disease | Sarcoidosis, Pulmonary | Congenital Myasthenic Syndrome | COACH Syndrome | Mast Cell Leukemia | Canavan Disease | Crisponi Syndrome | Cyclic Vomiting Syndrome | Carpenter Syndrome | Sclerosteosis 2 | Malonyl-CoA Decarboxylase Deficiency | Pontocerebellar Hypoplasia | Tinea Versicolor | Bullous Pemphigoid | Neurocutaneous Melanocytosis | Charcot-Marie-Tooth Disease Type 4 | Spinal Muscular Atrophy Type 3 | Anorexia Nervosa | Anterior Segment Dysgenesis | Cerebral Amyloid Angiopathy | Eccrine Porocarcinoma | Epilepsy Of Infancy With Migrating Focal Seizures | Lennox-Gastaut Syndrome | Myopathy | Neurodegeneration With Brain Iron Accumulation | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Chronic Lymphocytic Leukemia | Smith-Kingsmore Syndrome | Episodic Ataxia Type 2 | Dental Caries | Hypoparathyroidism | Hyperinsulinism-hyperammonemia Syndrome | Charcot-Marie-Tooth Disease, Type 1A | Pyruvate Kinase Deficiency | Bronchitis, Chronic | Hyperparathyroidism, Secondary | Atherosclerosis | Prostatitis | Traboulsi Syndrome | Dent Disease | Huntington's Disease-like 2 | Necrobiosis Lipoidica | Periodontitis | Retinopathy Of Prematurity | Glycogen Storage Disease Type 4 | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Skin Papilloma | Hypertension | Early Infantile Epileptic Encephalopathy 28 | Fibromuscular Dysplasia | Tenosynovial Giant Cell Tumor | Alexander Disease | Hemolytic Uremic Syndrome, Atypical | Autism | Trimethylaminuria | Hypoalbuminemia | Pancytopenia | Multiple Sclerosis | Thalassemia, Beta | Adrenomyeloneuropathy | Neurofibroma | 3-methylglutaconic Aciduria | Cardiofaciocutaneous Syndrome | Prediabetes | Myelofibrosis | Dystonia-parkinsonism, X-linked | Usher Syndrome Type III | Schamberg Disease | Epidermolysis Bullosa Acquisita | Klippel-Feil Syndrome | Goiter | Renal Hypomagnesemia 3 | Nestor-Guillermo Progeria Syndrome | Hyperparathyroidism, Primary | Myasthenia Gravis | Lichen Planus | REM Sleep Behavior Disorder | Neuroblastoma | Hereditary Coproporphyria | Neuronal Ceroid Lipofuscinosis | Arteriovenous Malformations | Histiocytosis | Mesothelioma, Malignant | Fanconi Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Acrodermatitis Enteropathica | Farber Disease | Netherton Syndrome | Pemphigus Vulgaris | Milk Allergy | Osteonecrosis Of The Jaw | Glomerulonephritis, Membranoproliferative | Alopecia Areata | Lymphomatoid Granulomatosis | Cystitis, Interstitial | Spinocerebellar Ataxia Type 1 | Pseudoexfoliation Syndrome | Cutaneous Lupus Erythematosus | Hepatitis B, Chronic | Lentigo | Erythema Multiforme | Crimean-Congo Hemorrhagic Fever | Intermittent Explosive Disorder | Pulmonary Alveolar Microlithiasis | Liver Failure, Acute Infantile | Inflammatory Linear Verrucous Epidermal Nevus | Pterygium | Moyamoya Disease | Reye Syndrome | Metachondromatosis | Joubert Syndrome 2 | Hepatitis C, Chronic | Paraganglioma | Nijmegen Breakage Syndrome | VACTERL Association | Toxic Epidermal Necrolysis | Fanconi Anemia | Benign Familial Neonatal Convulsions | GLUT1 Deficiency Syndrome | Pineoblastoma | Meningioma, Benign | Agnathia-Otocephaly Complex | Schuurs-Hoeijmakers Syndrome | Adenoma, Pituitary | Birk-Barel Syndrome | Acrodysostosis | Sleep Disorder | Cerebrovascular Disorders | Ebstein Anomaly | Hypobetalipoproteinemias | Primrose Syndrome | Metaphyseal Chondrodysplasia, Schmid Type | Relapsing Polychondritis | Spondylolisthesis | Carcinoid Tumor | Hypercholesterolemia, Familial | Geleophysic Dysplasia | Blastomycosis | Major Depression | Dysmorphophobia | Mitochondrial Cytopathy | Beckwith-Wiedemann Syndrome | Riboflavin Transporter Deficiency Neuronopathy | Multiple Sclerosis, Secondary Progressive | Myocarditis | Trichorhinophalangeal Syndrome | Spinal Cord Diseases | Hemochromatosis Type 1 | Anuria | Adenosine Deaminase Deficiency | Castleman Disease | Epidermolysis Bullosa Simplex | Woodhouse-Sakati Syndrome | Fibrodysplasia Ossificans Progressiva | Sialidosis | Spondylometaphyseal Dysplasia | Hemorrhage | Keratitis | Hyperoxaluria | Lysosomal Acid Lipase Deficiency | Addison Disease | Leukoencephalopathy, Progressive Multifocal | Dystonia Musculorum Deformans | Sporadic Hemiplegic Migraine | Antithrombin III Deficiency | Coronary Heart Disease | Hypotension, Orthostatic | Adenomatoid Tumor | Proximal Symphalangism | Thymoma, Malignant | Aldosterone Deficiency | Oculocutaneous Albinism Type 1 | Pneumonia, Bacterial | Hereditary Elliptocytosis | Erythrokeratodermia Variabilis | Antiphospholipid Syndrome | Aldosteronism | Carbonic Anhydrase VA Deficiency | Recurrent Respiratory Papillomatosis | Esophageal Adenocarcinoma | Spinal And Bulbar Muscular Atrophy | Rhabdomyosarcoma | Coronary Restenosis | Schwannoma | Chronic Inflammatory Demyelinating Polyneuropathy | Carcinoma In Situ | Imerslund-Grasbeck Syndrome | Headache | Congenital Nephrotic Syndrome | Large Granular Lymphocytic Leukemia | Renal Oncocytoma | Adenoid Cystic Carcinoma | Contact Dermatitis | Oligoastrocytoma | Bacterial Meningitis | Cervical Dystonia | Papillorenal Syndrome | Paroxysmal Kinesigenic Dyskinesia | Multicystic Renal Dysplasia | Pancreatitis, Chronic | Oral Lichen Planus | Episodic Ataxia Type 1 | Leber Hereditary Optic Neuropathy | Micro Syndrome | Glanzmann Thrombasthenia | Distal Myopathy 2 | Hereditary Inclusion Body Myopathy | Myoclonus-dystonia Syndrome | Porphyria, Acute Intermittent | Endometriosis | Retinal Diseases | Cleidocranial Dysplasia | Gangliosidosis, GM1 | Carcinoma, Signet Ring Cell | Meleda Disease | 3-methylcrotonyl-CoA Carboxylase Deficiency | Centronuclear Myopathy | Blastoma, Pleuropulmonary | Gastroenteritis | Chronic Granulomatous Disease | Waardenburg Syndrome Type 1 | Marshall-Smith Syndrome | Globozoospermia | Leukocyte Adhesion Deficiency | Lichen Sclerosus | Chronic Idiopathic Myelofibrosis | Cone Dystrophy | Tyrosinemia | Diastrophic Dysplasia | Still Disease | Donnai-Barrow Syndrome | Liddle Syndrome | Raine Syndrome | Takenouchi-Kosaki Syndrome | Corneal Neovascularization | Greig Cephalopolysyndactyly Syndrome | Iron Deficiency Anemia | Pseudo-pseudohypoparathyroidism | Cervicitis | Retinal Dystrophy | Vitamin B12 Deficiency | Meniere's Disease | Personality Disorders | Pierpont Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | Vestibular Disease | Chromosome 9q34.3 Deletion Syndrome | Glaucoma, Congenital | Obesity | Schizophrenia, Paranoid | LRBA Deficiency | Lateral Meningocele Syndrome | Lymphopenia