Pemphigus Vulgaris

About the Disease
Pemphigus Vulgaris, Familial, also known as pemphigus vulgaris, is related to pemphigus gestationis and ritter's disease. An important gene associated with Pemphigus Vulgaris, Familial is DSG3 (Desmoglein 3), and among its related pathways/superpathways are Innate Immune System and Nervous system development. The drugs Mycophenolic acid and Abatacept have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and neutrophil, and related phenotypes are feeding difficulties in infancy and atypical scarring of skin

Common Targets
SCN10A | CD3 Complex (T Cell Receptor Complex) | HLA-E | HLA-B | HLA-DRB1 | HLA-F | HLA-DMB | HLA-DQA1 | PIK3CD | TCF4 | HLA-A | IL-2 receptor | MOG | HLA-DOB | VPS37A | PIK3CA | HLA-L | LNCRNA-IUR | VDR | MS4A1 | TNFRSF13C | ST18 | MIF | CD28 | JAK3 | RIPK3 | HLA-C | HLA-DQB1 | PIK3CG | CD37 | HLA-DPB2 | SLC38A4 | BTK | ICOS | HCG17

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