Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Vasculitis | Cranioectodermal Dysplasia | Progressive Encephalopathy-optic Atrophy Syndrome | Osteonecrosis | Microvillus Inclusion Disease | Nager Acrofacial Dysostosis | Basal Ganglia Disease | Osteogenesis Imperfecta Type IV | Porphyria Cutanea Tarda | Schnyder Crystalline Corneal Dystrophy | Non-proliferative Diabetic Retinopathy | Hypercalciuria | Polycythemia Vera | Lactose Intolerance | GM2-gangliosidosis AB Variant | Postpartum Depression | Hydrocephalus | Hereditary Spherocytosis | Leukemia-lymphoma, Adult T-cell | Choriocarcinoma | Chondrodysplasia Punctata 1, X-linked Recessive | Carcinoma, Signet Ring Cell | Adrenomyeloneuropathy | Myocardial Infarction | Farber Disease | Sickle Cell Anemia | Brugada Syndrome 1 | Neurofibromatosis | Glaucoma, Congenital | Thyroiditis, Autoimmune | Isovaleric Acidemia | Birk-Barel Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Hyperparathyroidism-jaw Tumor Syndrome | Restless Legs Syndrome | Primary Erythromelalgia | Spinal Muscular Atrophy Type 2 | Pyruvate Carboxylase Deficiency Disease | Smith-Magenis Syndrome | Autonomic Nervous System Disorders | Tyrosine Hydroxylase Deficiency | Dystonia-parkinsonism, X-linked | Hereditary Pyropoikilocytosis | Harlequin Ichthyosis | Split Hand-foot Malformation | Infantile Liver Failure Syndrome 1 | Carpenter Syndrome | Malaria, Cerebral | Schindler Disease | Achondrogenesis | Combined Deficiency Of Factor V And Factor VIII | Congenital Heart Block | Facioscapulohumeral Muscular Dystrophy Type 1 | Beckwith-Wiedemann Syndrome | Glutathione Synthetase Deficiency | Amyotrophic Lateral Sclerosis, Juvenile | WAGR Syndrome | Spinocerebellar Ataxia Type 28 | VACTERL Association | Pineoblastoma | Perry Syndrome | Pontocerebellar Hypoplasia Type 7 | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Amelanotic Melanoma | Heterotopic Ossification | Tularemia | Lateral Meningocele Syndrome | Williams Syndrome | Metabolic Diseases | Barakat Syndrome | Chondrodysplasia Punctata 2, X-linked Dominant | Hereditary Mixed Polyposis Syndrome | Omenn Syndrome | Down Syndrome | Porphyria, Acute Intermittent | Schistosomiasis Mansoni | Intermittent Explosive Disorder | Hyperinsulinemia | Diffuse Palmoplantar Keratoderma | X-linked Acrogigantism | Cushing Syndrome | Rheumatic Heart Disease | Disseminated Intravascular Coagulation | Beta-Propeller Protein-associated Neurodegeneration | Avellino Corneal Dystrophy | Partington Syndrome | McLeod Syndrome | Exostoses | Cheilitis | Tinea Versicolor | FG Syndrome | Dysgerminoma | Mandibuloacral Dysplasia With Type A Lipodystrophy | Myopathy | Ependymoma | Multicentric Carpotarsal Osteolysis Syndrome | Spinocerebellar Ataxia Type 1 | Behavioral Variant Of Frontotemporal Dementia | Keratoconjunctivitis | Depression | Hereditary Elliptocytosis | T-cell Leukemia | Alpha-thalassemia Myelodysplasia Syndrome | Extramammary Paget's Disease | Pelizaeus-Merzbacher Disease | Constipation | Granuloma Annulare | Analgesia | Pelvic Inflammatory Disease | Hemangioendothelioma | Thyroid Hormone Resistance | Arthritis, Reactive | Anal Fissure | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Neurotoxicity | Presbyopia | Wolcott-Rallison Syndrome | Renal Medullary Carcinoma | Esophagitis, Eosinophilic | Polyradiculopathy | Aldosterone Deficiency | Basal Ganglia Cerebrovascular Disease | Carbohydrate Metabolism Disorders | Mood Disorder | Hydrolethalus Syndrome | Hereditary Inclusion Body Myopathy | Papillorenal Syndrome | Meier-Gorlin Syndrome | Hypercholesterolemia | Early Infantile Epileptic Encephalopathy | Mitochondrial DNA Depletion Syndrome | Menkes Disease | Hypotrichosis | Angelman Syndrome | Spinocerebellar Ataxia Type 15 | Charcot-Marie-Tooth Disease Axonal Type 2N | Trimethylaminuria | Aneurysm, Abdominal Aortic | Congenital Lipoid Adrenal Hyperplasia | Acute Motor Axonal Neuropathy | Renal Tubular Acidosis | Craniofacial Dysostosis | Pterygium | Venous Insufficiency | Cocaine-Related Disorders | Primary Biliary Cholangitis | Angioedema | Scleritis | Fragile X Syndrome | Retinopathy Of Prematurity | Relapsing Polychondritis | Waardenburg Syndrome | Chiari Malformation Type I | Guttate Psoriasis | Non-small Cell Lung Cancer | Dystonia | Albinism | Mucolipidosis Type II | Microcephaly, Seizures, And Developmental Delay | Ovarian Sex Cord-stromal Tumor | Spitzoid Melanoma | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Proximal Symphalangism | Metanephric Adenoma | Juvenile Hyaline Fibromatosis | Leri-Weill Dyschondrosteosis | Multiple Epiphyseal Dysplasia | Gingivitis | Spinocerebellar Ataxia Type 8 | Angiosarcoma Of The Breast | Pneumococcal Meningitis | Lassa Fever | Early Infantile Epileptic Encephalopathy 1 | Holt-Oram Syndrome | Intracerebral Hemorrhage | Hypertensive Nephropathy | Neurogenic Bladder | Wolfram Syndrome | Tuberculosis | Adenosine Deaminase Deficiency | Dental Caries | Spasticity | Adams-Oliver Syndrome | Papilloma | Keratosis, Actinic | Giant Cell Glioblastoma | Sarcoma, Alveolar Soft Part | Charcot-Marie-Tooth Disease Type 2E | Cardiomyopathy, Dilated, 1L | Muscle Wasting | Asthma | Hamartoma | Astigmatism | Shock, Cardiogenic | Vitamin K Deficiency | Cold Agglutinin Disease | Early Infantile Epileptic Encephalopathy 13 | Stevens-Johnson Syndrome | Incontinentia Pigmenti | Osteogenesis Imperfecta Type III | Endometrial Hyperplasia | Neuroectodermal Tumors, Primitive | Lipoma | Gangliosidosis, GM1 | Autoimmune Hemolytic Anemia | Idiopathic Multicentric Castleman Disease | Acute Myeloid Leukemia | Duane Retraction Syndrome | Spinocerebellar Ataxia Type 40 | Apert Syndrome | Common Cold | Lymphoma, Follicular | Dyggve-Melchior-Clausen Disease | Alstrom Syndrome | Hypertension, Essential | Mastitis | Hemochromatosis | Polyarteritis Nodosa | Sitosterolemia | Necrobiosis Lipoidica | Sialidosis Type I | Stuve-Wiedemann Syndrome | Pseudohypoaldosteronism | Marinesco-Sjogren Syndrome | Limb Girdle Muscular Dystrophy | Epilepsy, Generalized | Cardiofaciocutaneous Syndrome | Toxic Epidermal Necrolysis | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | REM Sleep Behavior Disorder | Chronic Idiopathic Myelofibrosis | Campomelic Dysplasia | Silicosis | Schistosomiasis | Nicotine Addiction | Macular Corneal Dystrophy Type 1 | Epiphyseal Chondrodysplasia, Miura Type | Postpoliomyelitis Syndrome | Myasthenia Gravis | Cervical Dystonia | Seizures | Specific Granule Deficiency | Amish Infantile Epilepsy Syndrome | Okihiro Syndrome | Pancreatitis, Chronic | Gitelman Syndrome | Diamond-Blackfan Anemia | Multiple Sclerosis, Relapsing-remitting | Micropenis | Fibrillation, Atrial | Cryopyrin-associated Periodic Syndromes | Trichotillomania | Skin Papilloma | Metachromatic Leukodystrophy | Angioimmunoblastic T-cell Lymphoma | Knobloch Syndrome | Loeys-Dietz Syndrome | Encephalitis, Tick-borne | Erectile Dysfunction | Schwannoma | Oligospermia | Parkinsonism | Congenital Bilateral Absence Of Vas Deferens | Bone Marrow Necrosis | Twin-to-twin Transfusion Syndrome | Atopy | Asplenia | Traboulsi Syndrome | CHARGE Syndrome | Vascular Cognitive Impairment | Retinal Dystrophy | Lennox-Gastaut Syndrome | Thin Basement Membrane Disease | Focal Facial Dermal Dysplasia | Hyperhomocysteinemia | Cancer, Prostate | Renal Tubular Dysgenesis | Corneal Dystrophy | Liver Failure | Congenital Ichthyosiform Erythroderma | Ectopia Lentis, Isolated, Autosomal Recessive | Congenital Primary Aphakia | Nail-Patella Syndrome | Schizophrenia | Tenosynovial Giant Cell Tumor | Veno-occlusive Disease | Osteoporosis | Glycogen Storage Disease Type 1 | Meleda Disease | Retinitis | Neurodegeneration With Brain Iron Accumulation | Angina Pectoris | T-cell Lymphoma, Subcutaneous Panniculitis-like | Wagner Disease | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Retinal Telangiectasia | Gilbert Syndrome | Precocious Puberty | HUPRA Syndrome | Moyamoya Disease | Pure Autonomic Failure | Kashin-Beck Disease | Osteomyelitis | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Epilepsy Of Infancy With Migrating Focal Seizures | Cirrhosis | Atrial Septal Defect | Primary Lateral Sclerosis | Erythromelalgia | Persistent Fetal Circulation | Hypertension, Pulmonary | Thrombophlebitis | Headache | Wilson's Disease | Craniosynostosis | Sclerosing Cholangitis | Rosacea | Trismus-pseudocamptodactyly Syndrome | Keratitis-ichthyosis-deafness Syndrome | Erythrokeratodermia Variabilis | Nestor-Guillermo Progeria Syndrome | Waardenburg Syndrome Type 4A | Renal Dysplasia | Alopecia Areata | Multisystemic Smooth Muscle Dysfunction Syndrome | Opisthorchiasis | Herpes Genitalis | Leishmaniasis, Cutaneous | Hypertension | Subacute Sclerosing Panencephalitis | Mumps | Bloom Syndrome | Panic Disorder | Dubin-Johnson Syndrome | Optic Nerve Hypoplasia, Bilateral | Hypersomnia | Osteoporosis, Postmenopausal | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Adenomyosis | Infertility | Ichthyosis Bullosa Of Siemens | Impulse Control Disorder | Pituitary Dwarfism | Androgenic Alopecia | Conjunctivitis | Kohlschutter-Tonz Syndrome | Kearns-Sayre Syndrome | Sporadic Inclusion Body Myositis | Chitayat Syndrome | Retinal Vasculitis | Cornelia De Lange Syndrome | Benign Recurrent Intrahepatic Cholestasis 1 | Usher Syndrome | Leiomyoma | Delirium | Myeloid Leukemia | Hyperinsulinemic Hypoglycemia | Familial Hypobetalipoproteinemia | Polymyalgia Rheumatica | Reflex Epilepsy | Neurocutaneous Syndromes | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Polyomavirus Nephropathy | Familial Cerebral Amyloid Angiopathy | Chronic Myelomonocytic Leukemia | Impetigo | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Hypoplastic Left Heart Syndrome | Mixed Connective Tissue Disease | Diabetes Gestational | Joubert Syndrome | Dominant Optic Atrophy | Coronary Restenosis | Schwartz-Jampel-Aberfeld Syndrome | Gestational Trophoblastic Disease | Tyrosinemia | Cramp Fasciculation Syndrome | Insulinoma | Familial Exudative Vitreoretinopathy | Hydronephrosis | Carey-Fineman-Ziter Syndrome | Glycogen Storage Disease Type 4 | DRESS Syndrome | Urolithiasis | Apraxia | Spinocerebellar Ataxia Type 27 | Colitis | Ventricular Septal Defect | PASLI Disease | Schizencephaly | Persistent Hyperplastic Primary Vitreous | Congenital Hemolytic Anemia | Glycogen Storage Disease Type 1b | Osteoporosis-pseudoglioma Syndrome | Kabuki Syndrome 2 | Corneal Dystrophies, Hereditary | Melnick-Needles Syndrome | Iron Deficiency Anemia | Cat Eye Syndrome | Hypospadias
