Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Jawad Syndrome | Pheochromocytoma | Congenital Hereditary Endothelial Dystrophy Type II | Pure Red Cell Aplasia | Vitamin D Deficiency | Multifocal Motor Neuropathy | Coffin-Lowry Syndrome | CDKL5 Deficiency Disorder | Joubert Syndrome | Coffin-Siris Syndrome | Hemoglobinopathies | Focal Segmental Glomerulosclerosis | Autonomic Neuropathy | Costello Syndrome | Spinocerebellar Ataxia Type 28 | Nail Disorder, Nonsyndromic Congenital | Cohen Syndrome | Cholangitis | Multiple Sulfatase Deficiency | Camurati-Engelmann Disease | Asplenia | Esthesioneuroblastoma | Cystitis, Interstitial | Prurigo Nodularis | Dental Caries | Porphyria | Pain | Hydrolethalus Syndrome | Pneumonia, Mycoplasma | Loeys-Dietz Syndrome | Alzheimer Disease, Late Onset | Nicotine Addiction | Hereditary Spherocytosis | Sponastrime Dysplasia | Hypophosphatasia | Paraganglioma | Basal Ganglia Disease | Iron Deficiency Anemia | Congenital Adrenal Hyperplasia 1 | Acromicric Dysplasia | Wolcott-Rallison Syndrome | Usher Syndrome Type I | Congenital Generalized Lipodystrophy | Hennekam Lymphangiectasia-lymphedema Syndrome | Pontocerebellar Hypoplasia Type 2 | Hypopigmentation | Pantothenate Kinase-associated Neurodegeneration | Focal Facial Dermal Dysplasia | Diabetes Insipidus | Lymphedema-distichiasis Syndrome | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Hemophagocytic Lymphohistiocytosis | Exotropia | Heart Septal Defects | Alstrom Syndrome | Asphyxia Neonatorum | Hemochromatosis Type 2 | Whipple's Disease | T-cell Chronic Lymphocytic Leukemia | Amblyopia | Trigonocephaly | Cutaneous Mastocytosis | Heavy Chain Disease | Chromosome 5q Deletion Syndrome | Chiari Malformation Type I | Mevalonate Kinase Deficiency | Acute Kidney Injury | Familial Hypertrophic Cardiomyopathy | Hypoglycemia | Takayasu's Arteritis | Tangier Disease | Myocardial Infarction | Diamond-Blackfan Anemia | Chronic Leukemia | Coloboma | Johanson-Blizzard Syndrome | Roberts Syndrome | Hyper IgE Syndrome | Measles | Stiff-man Syndrome | Hepatitis | Hypertension, Pulmonary | Retinal Coloboma | Retinoschisis | Neutrophilia | Waardenburg Syndrome | Nephroblastoma | Gilbert Syndrome | Isobutyryl-CoA Dehydrogenase Deficiency | Fraser Syndrome | Autosomal Recessive Spastic Paraplegia Type 54 | Periodic Limb Movement Disorder | Hepatoblastoma | Benign Hereditary Chorea | Lysosomal Acid Lipase Deficiency | Anodontia | Portal Vein Thrombosis | Esophageal Adenocarcinoma | T-cell Leukemia | Pleurisy | Membranous Nephropathy | Empyema | Osteomyelitis | Pseudohypoparathyroidism Type 1C | Liebenberg Syndrome | Cutaneous T-cell Lymphoma | Neuronal Ceroid Lipofuscinosis | Waardenburg Syndrome Type 4A | Disseminated Intravascular Coagulation | Osteitis | Cockayne Syndrome | Incontinentia Pigmenti | Cartilage Disorders | Angina Pectoris | Hepatitis, Alcoholic | Craniometaphyseal Dysplasia | Frank-ter Haar Syndrome | Chondroma | Agnathia-Otocephaly Complex | Glycogen Storage Disease Type 5 | Acrodysostosis | Parkinson's Disease | Monilethrix | Microcephaly, Seizures, And Developmental Delay | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Leukocyte Adhesion Deficiency | Agammaglobulinemia | Clouston Hidrotic Ectodermal Dysplasia | Crouzon Syndrome With Acanthosis Nigricans | Pouchitis | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Peripheral Neuropathy | Lipid Metabolism Disorders | Esophageal Carcinoma | Polyarteritis Nodosa | Pyruvate Carboxylase Deficiency Disease | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Greig Cephalopolysyndactyly Syndrome | Spinocerebellar Ataxia Type 27 | Adenomatoid Tumor | DICER1 Syndrome | VACTERL/VATER Association | Wiskott-Aldrich Syndrome | POEMS Syndrome | Porokeratosis | Tibial Muscular Dystrophy | Mitochondrial DNA Depletion Syndrome 13 | Basal Ganglia Disease, Biotin-responsive | Congenital Dyserythropoietic Anemia Type 4 | Craniofacial Dysostosis | Osteonecrosis Of The Jaw | Epithelial-myoepithelial Carcinoma | Hypoparathyroidism | Hereditary Inclusion Body Myopathy | Zimmermann-Laband Syndrome | Neuromyelitis Optica | Achondrogenesis | Methemoglobinemia Type IV | Hypogammaglobulinemia | Chronic Inflammatory Demyelinating Polyneuropathy | Hereditary Multiple Exostoses | Carey-Fineman-Ziter Syndrome | Hypothalamic Obesity | Takotsubo Cardiomyopathy | Budd-Chiari Syndrome | Gestational Trophoblastic Disease | Cutaneous Lupus Erythematosus | Dyggve-Melchior-Clausen Disease | Pilomatrix Carcinoma | Spinocerebellar Ataxia Type 20 | Infantile Nephropathic Cystinosis | Spitz Nevus | Sporadic Inclusion Body Myositis | Gliosarcoma | Cardiospondylocarpofacial Syndrome | Glutaric Aciduria Type 3 | Dystrophy, Cone-rod | Gastric Atrophy | Celiac Disease | LEOPARD Syndrome | Atrial Septal Defect | Oligospermia | Thyroiditis | Kernicterus | Chronic Idiopathic Myelofibrosis | Schistosomiasis | Brachydactyly | LRBA Deficiency | Tinea | Lipid Storage Myopathy | Idiopathic Multicentric Castleman Disease | Anorectal Malformations | Phosphoglycerate Dehydrogenase Deficiency | Hypokalemia | Lymphoproliferative Disease, X-linked | Cancer, Bladder | Nemaline Myopathy 10 | Bipolar Disorder | Impetigo | Neurofibrosarcoma | Lichen Planus | Epidermolysis Bullosa Simplex, Localized | Schwannoma | Thyroid Hormone Resistance | Stuttering | Primary Lateral Sclerosis | Diarrhea | Hyperostosis | Primary Hyperoxaluria Type 3 | Open-angle Glaucoma | Congenital Sodium Diarrhea | Beta-Propeller Protein-associated Neurodegeneration | Strabismus | Transcobalamin Deficiency | Hereditary Pyropoikilocytosis | Leukoplakia | Primary Biliary Cholangitis | Pancytopenia | Overactive Bladder | Keloid | Trimethylaminuria | T-cell Prolymphocytic Leukemia | Oligoasthenoteratozoospermia | Pontocerebellar Hypoplasia Type 7 | HELLP Syndrome | Acrodermatitis Enteropathica | 3-hydroxy-3-methylglutaric Aciduria | Birk-Barel Syndrome | Plasmacytoma | Sensory Neuropathy | Hypospadias | Paget's Disease Of The Breast | Metabolic Diseases | Hemorrhage | IgA Deficiency | Occipital Neuralgia | Osteonecrosis | Papulopustular Rosacea | Guillain-Barre Syndrome | Mitochondrial Myopathy | Ectodermal Dysplasia | Double Outlet Right Ventricle | Otopalatodigital Syndrome Type 2 | Cluster Headache | Amyotrophic Lateral Sclerosis | Glycogen Storage Disease Type 1 | Muir-Torre Syndrome | Chondromyxoid Fibroma | Hypocalcemia | Protein C Deficiency | Patent Foramen Ovale | Adenocarcinoma | Blue Nevus | Glioma | Multiple System Atrophy | Cysticercosis | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Retinal Dystrophy, Early-onset Severe | Carney-Stratakis Syndrome | Bainbridge-Ropers Syndrome | Vitreoretinopathy, Proliferative | Charcot-Marie-Tooth Disease Type 4B1 | Sclerosteosis | Chronic Enteropathy Associated With SLCO2A1 Gene | Cushing Syndrome | Pearson Syndrome | Retinal Degeneration | Scleroderma | Kashin-Beck Disease | Glaucoma, Congenital | Schistosomiasis Mansoni | Diffuse Intrinsic Pontine Glioma | Hydrops Fetalis | Amenorrhea | Genee-Wiedemann Syndrome | Cole-Carpenter Syndrome | Meier-Gorlin Syndrome | Eczema | Pituitary Stalk Interruption Syndrome | Colitis, Collagenous | Leukodystrophies | 3-methylcrotonyl-CoA Carboxylase Deficiency | Familial Exudative Vitreoretinopathy | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Ulcerative Colitis | Rosacea | Carbamoyl Phosphate Synthetase I Deficiency | Gyrate Atrophy Of The Choroid And Retina | Psoriasis | Osteochondroma | NDH Syndrome | Treacher Collins Syndrome | Bullous Pemphigoid | Majeed Syndrome | C3 Glomerulopathy | Ichthyosis | Premenstrual Syndrome | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Gingivitis | Xeroderma Pigmentosum Variant Type | Bronchitis, Chronic | Speech Disorders | Impulse Control Disorder | Shwachman-Bodian-Diamond Syndrome | Hyperinsulinism-hyperammonemia Syndrome | McCune-Albright Syndrome | Optic Neuropathy, Anterior Ischemic | Acute Tubular Necrosis | Glutathione Synthetase Deficiency | Acute Lymphocytic Leukemia | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Diabetes Type 1 | Kawasaki Disease | Spondylosis | Richter's Syndrome | Tremor | Cellulitis | Major Depression | Tendinitis | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Hepatitis, Autoimmune | Duane Retraction Syndrome | Tay-Sachs Disease | Acute Leukemia | Hemophilia | Takenouchi-Kosaki Syndrome | Absence Epilepsy | Subacute Sclerosing Panencephalitis | Palmoplantar Keratoderma | Spinocerebellar Ataxia Type 8 | Optic Neuritis | Hemangioendothelioma | Carcinoid Tumor | Hereditary Mixed Polyposis Syndrome | Blepharo-cheilo-odontic Syndrome | Retinal Telangiectasia | Encephalopathy, Glycine | Fanconi Anemia | Steel Syndrome | Nance-Horan Syndrome | Noonan Syndrome | Corneal Dystrophies, Hereditary | Hidradenitis Suppurativa | Blepharospasm | Cryptococcal Meningitis | Left Ventricular Noncompaction | Facioscapulohumeral Muscular Dystrophy | Sezary Syndrome | Benign Familial Pemphigus | Osteoporosis | Arthritis, Gouty | Feingold Syndrome | Calcium Pyrophosphate Deposition Disease | Malonyl-CoA Decarboxylase Deficiency | Turner's Syndrome | Cerebrotendinous Xanthomatosis | Larsen Syndrome | 5-oxoprolinase Deficiency | Lymphoma, AIDS-related | Hoyeraal-Hreidarsson Syndrome | Ependymoma | Trichothiodystrophy | Paraganglioma, Carotid Body | Meckel-Gruber Syndrome | Vertigo | Stuve-Wiedemann Syndrome | Hepatitis C, Chronic | Bare Lymphocyte Syndrome | Gnathodiaphyseal Dysplasia | Congenital Muscular Dystrophy | Ocular Surface Squamous Neoplasia | Short-chain Acyl-CoA Dehydrogenase Deficiency | Rett Syndrome | Skin Fragility-woolly Hair Syndrome | Spinocerebellar Ataxia Type 17 | Cataplexy | Mountain Sickness | Polycystic Liver | Neuroleptic Malignant Syndrome | Congenital Stationary Night Blindness | Sengers Syndrome | Bronchiectasis | Carbonic Anhydrase VA Deficiency | Pre-eclampsia | Carcinoma, Signet Ring Cell | Bladder Exstrophy | Pleomorphic Xanthoastrocytoma | Trichorhinophalangeal Syndrome | Lymphoproliferative Disorders | Intermittent Claudication | Herpes Genitalis | Cholestasis, Intrahepatic | Choriocarcinoma | Personality Disorders | Acne | Pneumothorax | Precocious Puberty | Moyamoya Disease | Depression | Graft-versus-host Disease
