Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Citrullinemia | Phosphoglycerate Dehydrogenase Deficiency | Polycystic Liver | Wolff-Parkinson-White Syndrome | Succinic Semialdehyde Dehydrogenase Deficiency | Patent Ductus Arteriosus | Chromosome 8q21.11 Deletion Syndrome | Esophageal Motility Disorders | Duane Retraction Syndrome | Hereditary Hemorrhagic Telangiectasia | Alveolar Capillary Dysplasia | Coma | H Syndrome | Twin-to-twin Transfusion Syndrome | Sepiapterin Reductase Deficiency | Pheochromocytoma | Pregnancy, Ectopic | Oculocutaneous Albinism Type 1 | Exostoses | Sponastrime Dysplasia | Delayed Sleep Phase Syndrome | Hepatitis D | Charcot-Marie-Tooth Disease, Type 2 | Endocarditis | Speech Disorders | Tuberculous Meningitis | Tyrosinemia | Kashin-Beck Disease | Wieacker-Wolff Syndrome | Sick Sinus Syndrome | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Alexander Disease | Intermittent Explosive Disorder | Hennekam Lymphangiectasia-lymphedema Syndrome | Cervicitis | Pycnodysostosis | N-acetylglutamate Synthase Deficiency | GAPO Syndrome | Paraplegia | Cranioectodermal Dysplasia | Measles | Glutathione Synthetase Deficiency | Kearns-Sayre Syndrome | Blue Nevus | Glaucoma, Congenital | Malaria, Cerebral | Erythrokeratodermia Variabilis | Multiple Sclerosis, Relapsing-remitting | Imerslund-Grasbeck Syndrome | Metachromatic Leukodystrophy | Astigmatism | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Chronic Thromboembolic Pulmonary Hypertension | Ischemia | Multisystemic Smooth Muscle Dysfunction Syndrome | Subacute Sclerosing Panencephalitis | Impulse Control Disorder | Ileitis | Alagille Syndrome | Myeloid Leukemia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Autism Spectrum Disorders | Cutaneous Lupus Erythematosus | Congenital Afibrinogenemia | Persistent Mullerian Duct Syndrome | Gout | Charcot-Marie-Tooth Disease, Type 6 | Peutz-Jeghers Syndrome | Headache | Myosin Storage Myopathy | Xeroderma Pigmentosum Variant Type | T-cell Lymphoma, Subcutaneous Panniculitis-like | Meningococcal Infections | Parapsoriasis | Epilepsy, Generalized | Essential Fructosuria | Woodhouse-Sakati Syndrome | Cardiomyopathy, Dilated, 1L | Urolithiasis | Dyskeratosis Congenita | Rhabdomyosarcoma, Alveolar | Membranous Nephropathy | Charcot-Marie-Tooth Disease Type 4D | C3 Glomerulonephritis | Placenta Previa | Anti-glomerular Basement Membrane Disease | Renal-hepatic-pancreatic Dysplasia | Multiple Hamartoma Syndrome | Primrose Syndrome | Noonan Syndrome | Fibromyalgia | Meier-Gorlin Syndrome | Mucolipidosis | Neutrophilia | Hereditary Sensory Neuropathy Type 1 | Ameloblastoma | Norrie Disease | Aceruloplasminemia | Schwannoma | Oligospermia | Lymphoproliferative Disease, X-linked | Rhabdomyosarcoma | Infertility, Male | Cholangiocarcinoma | Hyperoxaluria | Gigantism | Epiphyseal Chondrodysplasia, Miura Type | Scleritis | Amenorrhea | Thrombophlebitis | Whipple's Disease | Myelitis, Transverse | Hamartoma | Autoimmune Polyendocrine Syndrome | Congenital Torticollis | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Agnathia-Otocephaly Complex | Plasmacytoma | Actinomycetoma | Chondroma | Oculopharyngeal Muscular Dystrophy | Familial Exudative Vitreoretinopathy | Alpha-mannosidosis | Smoldering Myeloma | Necrotizing Autoimmune Myopathy | Macrophage Activation Syndrome | Fibrosis | Amyotrophic Lateral Sclerosis, Juvenile | Jawad Syndrome | Farber Disease | Rhabdoid Tumor | Hepatorenal Syndrome | Glycogen Storage Disease Type 6 | Multiple Sclerosis, Primary Progressive | Polymicrogyria | Creatine Deficiency Syndrome | Dermatomyositis | Spondyloperipheral Dysplasia | Meconium Ileus | CREST Syndrome | Facioscapulohumeral Muscular Dystrophy Type 1 | Currarino Syndrome | Exocrine Pancreatic Insufficiency | Spinocerebellar Ataxia Type 10 | Disseminated Intravascular Coagulation | Syncope | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Generalized Epilepsy With Febrile Seizures Plus | Major Depression | Proteasome-associated Autoinflammatory Syndrome 2 | Binge Eating Disorder | Retinal Diseases | Reticular Dysgenesis | Sertoli Cell-only Syndrome | Autosomal Recessive Spastic Paraplegia Type 35 | Choroiditis | Heroin Dependence | Spinocerebellar Ataxia Type 28 | Tyrosine Hydroxylase Deficiency | Angina Pectoris | Hypertelorism | Methemoglobinemia | Portal Vein Thrombosis | Temtamy Preaxial Brachydactyly Syndrome | Muscular Dystrophy | Carbonic Anhydrase VA Deficiency | Diabetic Macular Edema | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Neuromyelitis Optica | Astrocytoma, Anaplastic | Sickle Cell Disease | Tic Disorder | Hairy Cell Leukemia | Premenstrual Syndrome | Congenital Disorders Of Glycosylation | Plasma Cell Leukemia | Benign Familial Neonatal Convulsions | Brenner Tumor | Light Chain Amyloidosis | Aphasia | Porphyria Cutanea Tarda | Hypertensive Retinopathy | Congenital Absence Of Vas Deferens | Myocarditis | Analgesia | Tricho-hepato-enteric Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Chondrodysplasia Punctata | Intellectual Disability, Autosomal Dominant 5 | Trismus-pseudocamptodactyly Syndrome | Non-small Cell Lung Cancer | Neurocutaneous Syndromes | Neuroblastoma | Vertebrobasilar Insufficiency | Neuropathy | Dysplastic Nevus | Craniofrontonasal Syndrome | Cardiomyopathy, Restrictive | Lateral Meningocele Syndrome | Ichthyosis Bullosa Of Siemens | Diabetic Encephalopathy | Hyperostosis | Joubert Syndrome 2 | Erythromelalgia | Acral Lentiginous Melanoma | Aromatic L-amino Acid Decarboxylase Deficiency | Dysfibrinogenemia | Muscle Wasting | AIDS Dementia Complex | Fucosidosis | Hyper IgE Syndrome | Stiff-man Syndrome | Autonomic Nervous System Disorders | Cholestasis | Johanson-Blizzard Syndrome | Anxiety Disorders | Mitochondrial Cytopathy | Zollinger-Ellison Syndrome | Immunoproliferative Disorders | Fukuyama Congenital Muscular Dystrophy | Congenital Tufting Enteropathy | Mitochondrial Disease | Myoclonus | Lymphedema | Alkaptonuria | DICER1 Syndrome | Shock, Cardiogenic | CHOPS Syndrome | Pseudohypoaldosteronism | Aspergillosis | Hepatic Veno-occlusive Disease | Schwannomatosis | Meesmann Corneal Dystrophy | Pompe Disease | Insulin Resistance | Nasodigitoacoustic Syndrome | Acrodermatitis | Hypervalinemia | Chorea-acanthocytosis | Lattice Corneal Dystrophy Type 1 | Allergic Contact Dermatitis | Lafora Disease | Spondylocarpotarsal Synostosis Syndrome | Persistent Truncus Arteriosus | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Aldosterone Deficiency | Steel Syndrome | DNA Ligase IV Deficiency | Tetraplegia | IMAGe Syndrome | Werner's Syndrome | Apparent Mineralocorticoid Excess Syndrome | Anuria | Fahr Disease | Gitelman Syndrome | Methemoglobinemia Type IV | Familial Partial Lipodystrophy | Ulcerative Colitis | Choroideremia | Common Cold | Nicotine Addiction | Heart Septal Defects | Gray Platelet Syndrome | Aldosteronism | Lymphoma, Mantle Cell | Osteoporosis | Alcoholism | Trichotillomania | Chromosome 16p11.2 Deletion Syndrome | Spinocerebellar Ataxia Type 42 | Camptocormia | Hoyeraal-Hreidarsson Syndrome | Sarcoma, Ewing | Retinal Dystrophy, Early-onset Severe | Primary Lateral Sclerosis | Hepatitis, Autoimmune | Systemic Lupus Erythematosus | Overactive Bladder | Senior-Loken Syndrome | Adult Polyglucosan Body Disease | Microphthalmia, Syndromic 7 | Left Ventricular Noncompaction | Palsy, Cerebral | HELLP Syndrome | Niemann-Pick Disease | Glaucoma | Pyloric Stenosis, Infantile Hypertrophic | Hypoproteinemia, Hypercatabolic | Renal Oncocytoma | Aplastic Anemia | Congenital Dyserythropoietic Anemia Type 1 | Alopecia Totalis | Megaloblastic Anemia | Cerebellofaciodental Syndrome | Spinocerebellar Ataxia Type 27 | Pleurisy | Autoimmune Disease | Hyperphenylalaninemia | Blomstrand Osteochondrodysplasia | Multicystic Renal Dysplasia | Alpers Syndrome | Lassa Fever | Hidradenitis | Cornelia De Lange Syndrome | Recurrent Respiratory Papillomatosis | Acute Tubular Necrosis | Geleophysic Dysplasia | Occipital Neuralgia | Eiken Syndrome | Chiari Malformation Type I | Metaphyseal Chondrodysplasia, Schmid Type | Dyggve-Melchior-Clausen Disease | Oral Lichen Planus | Waardenburg Syndrome Type 4A | Carcinoma, Merkel Cell | Brachydactyly | Neurofibromatosis-Noonan Syndrome | Thrombotic Microangiopathy | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Erdheim-Chester Disease | Jacobsen Syndrome | Hepatitis, Chronic | Endometriosis | Colitis, Collagenous | Progressive Familial Intrahepatic Cholestasis | Intestinal Hypomagnesemia 1 | Hemochromatosis Type 2 | Waardenburg Syndrome Type 4 | Adrenal Insufficiency | Dysferlinopathy | Polyneuropathy | Pemphigus Vulgaris | Hyperparathyroidism, Primary | Thyroiditis, Autoimmune | Nevus | Strabismus | Rolandic Epilepsy | Hydrolethalus Syndrome | Ectodermal Dysplasia | Vitiligo | Pancreatitis, Chronic | Non-proliferative Diabetic Retinopathy | Pleural Tuberculosis | Trimethylaminuria | Hypercholesterolemia | Uremic Pruritus | Sarcomatoid Carcinoma Of The Lung | Withdrawal Syndrome | Juvenile Polyposis | Holt-Oram Syndrome | Cannabis Abuse | Leukoencephalopathy, Progressive Multifocal | Microcephaly, Seizures, And Developmental Delay | Kaposi Sarcoma | Fetal Akinesia Deformation Sequence | High Molecular Weight Kininogen Deficiency | Presbyopia | Hyperinsulinemia | Progressive External Ophthalmoplegia | Parkinson Disease 6, Autosomal Recessive Early-onset | Malnutrition | Conjunctivitis | Mabry Syndrome | Schizoaffective Disorder | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Nephrocalcinosis | Lysosomal Acid Lipase Deficiency | Hypertension, Renal | Antisynthetase Syndrome | Charcot-Marie-Tooth Disease Axonal Type 2N | Metatropic Dysplasia | Charcot-Marie-Tooth Disease Type 4B1 | Papilloma | Shwachman-Bodian-Diamond Syndrome | Salla Disease | Hereditary Coproporphyria | Vestibular Disease | Focal Segmental Glomerulosclerosis | Eosinophilia | Thymoma, Malignant | Progressive Myoclonic Epilepsy | Huntington's Disease | Auriculocondylar Syndrome | Osteopetrosis | Kaposiform Hemangioendothelioma | Mucormycosis | Sick Sinus Syndrome 1 | Hepatic Steatosis | Cystinosis | Charcot-Marie-Tooth Disease Type 2T | Glycogen Storage Disease Type 1 | Hyperparathyroidism | Bipolar Disorder | Hypobetalipoproteinemias | Pemphigus | Diverticulitis | Peripheral Neuropathy | Neurofibroma, Plexiform | Alstrom Syndrome | Inflammatory Myopathy