Disease

Pemphigus

About the Disease
Pemphigus is related to pemphigus erythematosus and herpetiform pemphigus, and has symptoms including exanthema and pruritus. An important gene associated with Pemphigus is DSG3 (Desmoglein 3), and among its related pathways/superpathways are Nervous system development and Programmed Cell Death. The drugs Prednisone and Mycophenolic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and neutrophil, and related phenotypes are no effect and no effect

Common Targets
HLA-A | NR1H3 | FCGRT | GSK3B | BMX | ABCA1 | ATP13A5 | MS4A1 | MOG | DSG3 | Proteasome Complex | FASLG | CCR5 | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | ERBB4 | LNCRNA-IUR | HLA-DQB1 | HLA-DPB1 | ATP9B | DHFR | HLA-DRB1 | G2475 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | CD19 | TLR7 | BTK | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | ST18 | HCAR2 | HLA-B | G7124 | PLAAT1 | SCN10A | PIK3CD | DSG1 | TXK | SLC38A4 | C5 | ATP11A | Folate Receptor (nonspecified subtype) | TEC

疾病靶点研报
Pemphigus

Note: If you'd like to get a target analysis report for Pemphigus, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Pemphigus at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Blue Rubber Bleb Nevus Syndrome | Menkes Disease | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Mitochondrial Disease | Obesity, Morbid | Hepatitis C, Chronic | Arthritis, Reactive | Budd-Chiari Syndrome | Galloway-Mowat Syndrome | Chromosome 8q21.11 Deletion Syndrome | Endometritis | Raine Syndrome | Werner's Syndrome | Pulmonary Alveolar Microlithiasis | Ichthyosis, X-linked | Schuurs-Hoeijmakers Syndrome | Triphalangeal Thumb-polysyndactyly Syndrome | Adenoma, Pleomorphic | Inflammatory Myopathy | Riboflavin Transporter Deficiency Neuronopathy | Cleidocranial Dysplasia | Light Chain Amyloidosis | Adenomatoid Tumor | Thymoma, Malignant | Ataxia-ocular Apraxia 2 | Learning Disability | Crohn's Disease | Chronic Idiopathic Myelofibrosis | Familial Mediterranean Fever | Thyroid Dysgenesis | Stevens-Johnson Syndrome | Adenoma, Villous | FG Syndrome | Disseminated Superficial Actinic Porokeratosis | Hypermetropia | Hypoparathyroidism | Atelosteogenesis Type 1 | Hydrocephalus, Normal Pressure | Membranous Nephropathy | Myofibrillar Myopathy | Spondylolisthesis | Charcot-Marie-Tooth Disease Type 3 | Glomerulonephritis, Membranoproliferative | Papillorenal Syndrome | Sporadic Hemiplegic Migraine | Osteomyelitis | Sickle Cell Disease | Hyperandrogenemia | Spinal And Bulbar Muscular Atrophy | Acute Myeloid Leukemia | Tumoral Calcinosis | Early Infantile Epileptic Encephalopathy 1 | Osteopathia Striata With Cranial Sclerosis | Spinocerebellar Ataxia Type 27 | Peritonitis | Leigh Syndrome | Neuropathy | Pulmonary Stenosis | Glycogen Storage Disease | Mandibuloacral Dysplasia With Type A Lipodystrophy | T-cell Leukemia | Familial Hypobetalipoproteinemia | Familial Digital Arthropathy-brachydactyly | Wolfram Syndrome 2 | Williams Syndrome | Presbyopia | Yellow Fever | Klippel-Feil Syndrome | Hyperbilirubinemia | Leukoencephalopathy, Progressive Multifocal | Costello Syndrome | Blue Nevus | Avian Influenza | Persistent Truncus Arteriosus | Cannabis Abuse | Jawad Syndrome | Usher Syndrome Type II | Hypoplastic Left Heart Syndrome | Saul-Wilson Syndrome | Von Willebrand Disease | Ocular Surface Squamous Neoplasia | Huntington's Disease-like 2 | Aldosteronism | Prune Belly Syndrome | Withdrawal Syndrome | Hyperthermia, Malignant | Acute Generalized Exanthematous Pustulosis | Angelman Syndrome | Neuroma | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Trigonocephaly | Nemaline Myopathy 8 | Sturge-Weber Syndrome | Keratosis, Seborrheic | Kindler Syndrome | Non-Langerhans Cell Histiocytosis | Mitochondrial Encephalomyopathy | Aldosterone Synthase Deficiency | Benign Familial Pemphigus | Vascular Cognitive Impairment | Chordoma | Multiple Epiphyseal Dysplasia | Adenocarcinoma | Pitt-Hopkins Syndrome | Ovarian Hyperstimulation Syndrome | Fetal Alcohol Syndrome | DICER1 Syndrome | Hemoglobinopathies | Aldosterone Deficiency | Spinocerebellar Ataxia Type 17 | Renal Hypouricemia | Brachydactyly | Stargardt Disease | Nephrosclerosis | Esophagitis | Neuroectodermal Tumors, Primitive | Placenta Previa | Triple A Syndrome | McKusick Type Metaphyseal Chondrodysplasia | Nicolaides-Baraitser Syndrome | Echinococcosis | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Connective Tissue Disorders | Chediak-Higashi Syndrome | Progressive Familial Intrahepatic Cholestasis Type 1 | Proximal Symphalangism | Neuromyotonia | Stroke, Ischemic | Carcinoma, Transitional Cell | Erectile Dysfunction | Silicosis | HANAC Syndrome | Lissencephaly 2 | Methylmalonic Aciduria And Homocystinuria, CblC Type | Angioedema | Familial Cerebral Amyloid Angiopathy | Primary Hyperoxaluria | Tyrosinemia | Influenza | Relapsing Polychondritis | Temporal Lobe Epilepsy | Intermittent Explosive Disorder | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Primary Biliary Cholangitis | Endophthalmitis | Herpes Simplex Dermatitis | Metanephric Adenoma | Osteochondroma | Bursitis | Cramp Fasciculation Syndrome | Portal Vein Thrombosis | Papilledema | Shprintzen-Goldberg Syndrome | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Keratoconus | Spinocerebellar Ataxia Type 7 | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Atopy | Proteasome-associated Autoinflammatory Syndrome 2 | Fukuyama Congenital Muscular Dystrophy | Sclerosteosis | PHARC Syndrome | Nemaline Myopathy | Pemphigoid | Leiomyosarcoma | Behcet's Disease | T-cell Lymphoma, Subcutaneous Panniculitis-like | Fahr Disease | Polycystic Kidney, Autosomal Dominant | Spinocerebellar Ataxia Type 2 | Hypereosinophilic Syndrome | Idiopathic Multicentric Castleman Disease | Spastic Paraplegia Type 7 | Cole-Carpenter Syndrome | Chudley-McCullough Syndrome | NDH Syndrome | Ichthyosis Bullosa Of Siemens | Angioimmunoblastic T-cell Lymphoma | Premature Ejaculation | Glycogen Storage Disease Type 0, Muscle | Holoprosencephaly | Bloom Syndrome | Netherton Syndrome | High Molecular Weight Kininogen Deficiency | Hypertensive Retinopathy | Granular Corneal Dystrophy | Aplasia Cutis Congenita | Ghosal Syndrome | Peutz-Jeghers Syndrome | Dominant Optic Atrophy | Ollier Disease | Pulmonary Veno-occlusive Disease | Odonto-onycho-dermal Dysplasia | Vici Syndrome | Basan Syndrome | Herpes Genitalis | Impetigo | Spermatocele | Senior-Loken Syndrome | Microtia | GM2-gangliosidosis AB Variant | Polyradiculopathy | Peters-plus Syndrome | Knobloch Syndrome | Bipolar Disorder | Cervical Dystonia | Pierre Robin Syndrome | Granular Corneal Dystrophy Type 1 | Kearns-Sayre Syndrome | Arterial Tortuosity Syndrome | IgA Deficiency | Huntington's Disease | Varicocele | Long QT Syndrome Type 2 | Methemoglobinemia Type IV | Macular Corneal Dystrophy Type 1 | Exotropia | Eczema | Cyst | Oculopharyngeal Muscular Dystrophy | Dystrophy, Cone-rod | Epidermolytic Ichthyosis, Annular | Cavitary Optic Disc Anomalies | Chondrosarcoma | Cholera | Primary Sclerosing Cholangitis | Hyperkeratosis | Optic Neuritis | Pneumonia, Viral | Intestinal Pseudo-obstruction | Hypercholesterolemia, Familial | Maternally Inherited Diabetes And Deafness | Osteosarcoma | Juvenile Polyposis | 3-hydroxy-3-methylglutaric Aciduria | Congenital Myasthenic Syndrome | Hemorrhoids | Chloridorrhea, Congenital | Fowler's Syndrome | Anthrax | Cheilitis | Hidradenitis Suppurativa | Lassa Fever | Myoclonic Epilepsy With Ragged Red Fibers | Carcinoma, Signet Ring Cell | Acne | Communication Disorders | Blepharitis | Leishmaniasis, Cutaneous | Temtamy Preaxial Brachydactyly Syndrome | Sarcoma, Alveolar Soft Part | CDKL5 Deficiency Disorder | Retinitis Pigmentosa | Coronary Heart Disease | Peeling Skin Syndrome, Acral Type | Cone Dystrophy | Bronchitis | Bone Marrow Necrosis | Swine Influenza | Amebiasis | Spinocerebellar Ataxia Type 15 | Ebstein Anomaly | Norrie Disease | Dysplastic Nevus | Neurofibrosarcoma | Osteoporosis, Postmenopausal | Mucolipidosis Type IV | Basal Ganglia Disease | Pneumococcal Meningitis | Hemangioblastoma | Sialidosis Type I | Schizencephaly | Porphyria, Variegate | Asplenia | Carey-Fineman-Ziter Syndrome | Gingivitis | Blepharo-cheilo-odontic Syndrome | Histoplasmosis | Infantile Nephropathic Cystinosis | Blepharospasm | Stromal Corneal Dystrophy | Lafora Disease | Juvenile Xanthogranuloma | Rosacea | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Hypohidrotic Ectodermal Dysplasia | Colitis, Microscopic | Leukocyte Adhesion Deficiency Type 1 | Poretti-Boltshauser Syndrome | Down Syndrome | Low Phospholipid Associated Cholelithiasis | Rolandic Epilepsy | Liver Failure | Autoimmune Disease | Cryptococcal Meningitis | Lymphoma, AIDS-related | Urofacial Syndrome | Oligoastrocytoma | Colon Adenoma | Smith-Kingsmore Syndrome | Contact Dermatitis | Generalized Epilepsy And Paroxysmal Dyskinesia | Vascular Calcification | Pantothenate Kinase-associated Neurodegeneration | Atopic Dermatitis | Polymyositis | Non-epidermolytic Palmoplantar Keratoderma | Arteriosclerosis | CREST Syndrome | Adenosine Deaminase Deficiency | Osteosclerosis | Long QT Syndrome Type 3 | Coma | Esophagitis, Eosinophilic | Chromosome 17q21.31 Deletion Syndrome | Distal Myopathy | Renal Tubular Acidosis | Hennekam Lymphangiectasia-lymphedema Syndrome | Aicardi-Goutieres Syndrome | Reticular Dysgenesis | Necrobiosis Lipoidica | Graves Disease | Carcinoid Syndrome | Leukocyte Adhesion Deficiency | Hypervalinemia | Bartter Syndrome | Hypertension, Portal | Ophthalmia, Sympathetic | Alzheimer Disease, Late Onset | Hyperparathyroidism-jaw Tumor Syndrome | Narcolepsy | Neurocutaneous Syndromes | Major Depression | Turner's Syndrome | Osteitis | ADNP Syndrome | Discoid Lupus Erythematosus | Pneumoconiosis | Wolman Disease | Obesity | Myoclonus-dystonia Syndrome | Keratosis, Actinic | Nephritis, Interstitial | Pycnodysostosis | Cryptosporidiosis | Argininosuccinic Aciduria | Glutaric Aciduria Type 2 | Spinocerebellar Ataxia Type 28 | Glutaric Aciduria Type 1 | Sensory Neuropathy | Blood Protein Disorders | Atelosteogenesis Type 2 | Amelogenesis Imperfecta | Glutathione Synthetase Deficiency | Aphasia | MELAS Syndrome | VACTERL/VATER Association | Hyperammonemia | Atrial Septal Defect | Left Ventricular Noncompaction | Hepatic Adenomatosis | Compartment Syndrome | Paracoccidioidomycosis | Recurrent Respiratory Papillomatosis | Erythrokeratodermia Variabilis | Superficial Spreading Melanoma | Epithelioid Hemangioma | Pneumothorax | Perivascular Epithelioid Cell Tumor | Prolymphocytic Leukemia | Glioblastoma Multiforme | Myelitis, Transverse | McCune-Albright Syndrome | IgA Nephropathy | Oculocutaneous Albinism Type 4 | Cholelithiasis | Central Core Disease | Alveolar Capillary Dysplasia | Stroke | Lymphedema | Binge Eating Disorder | Cerebrotendinous Xanthomatosis | Hepatic Veno-occlusive Disease | Angioedema, Acquired | Thyrotoxic Periodic Paralysis | Spinal Muscular Atrophy Type 3 | Endometrial Hyperplasia | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Macrophage Activation Syndrome | Shwachman-Bodian-Diamond Syndrome | Hereditary Elliptocytosis | Retinal Degeneration | Lysosomal Acid Lipase Deficiency | Hepatitis A | Chronic Periodontitis | Agoraphobia | Osteogenesis Imperfecta Type IV | Wilson's Disease | Inflammatory Linear Verrucous Epidermal Nevus | Barrett Esophagus