Disease

Long QT Syndrome Type 3

About the Disease
Long Qt Syndrome 3, also known as lqt3, is related to long qt syndrome 6 and brugada syndrome 1, and has symptoms including syncope An important gene associated with Long Qt Syndrome 3 is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways/superpathways are Activation of cAMP-Dependent PKA and Cardiac conduction. The drugs Ranolazine and Sodium Channel Blockers have been mentioned in the context of this disorder. Affiliated tissues include heart, skeletal muscle and endothelial, and related phenotypes are sudden cardiac death and prolonged qtc interval

Common Targets
Sodium channel (nonspecified subtype) | SCN5A

疾病靶点研报
Long QT Syndrome Type 3

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