Batten Disease

About the Disease
Ceroid Lipofuscinosis, Neuronal, 3, also known as batten disease, is related to ceroid lipofuscinosis, neuronal, 1 and neuronal ceroid-lipofuscinoses, and has symptoms including myoclonus, seizures and abnormality of extrapyramidal motor function. An important gene associated with Ceroid Lipofuscinosis, Neuronal, 3 is CLN3 (CLN3 Lysosomal/Endosomal Transmembrane Protein, Battenin). The drugs Prednisolone phosphate and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include eye, heart and bone marrow, and related phenotypes are developmental regression and motor deterioration

Common Targets
TPP1 | UGCG | SORT1 | CLN3 | CLN6 | Chaperone (nonspecified subtype) | SLC5A4 | GAA | VCP | MFSD8 | PPT1

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