Disease

Anemia

About the Disease
Deficiency Anemia, also known as anemia, is related to iron deficiency anemia and diamond-blackfan anemia, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Deficiency Anemia is HBA2 (Hemoglobin Subunit Alpha 2), and among its related pathways/superpathways are Cellular responses to stimuli and Binding and Uptake of Ligands by Scavenger Receptors. The drugs Iron protein succinylate and Proguanil have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, kidney and heart, and related phenotypes are homeostasis/metabolism and liver/biliary system

Common Targets
EGLN3 | VDR | INPP5D | MAP3K4 | VHL | OAS1 | G5743 | IL13 | SULT1A1 | GSTP1 | UGT1A10 | BDKRB2 | MTHFR | SLC28A2 | MMP1 | HMOX1 | Histone deacetylase (nonspecified subtype) | MAP2K4 | CSNK1E | HUS1 | HCK | Prolyl 4-hydroxylase | XRCC1 | PIK3CG | HAMP | SLC28A3 | DPYD | CTNNB1 | G5599 | CSF3 | FFAR4 | XPC | G5243 | G1026 | MAP2K7 | ST14 | P2Y purinoceptor (nonspecified subtype) | FAP | ERCC1 | ABL1 | UGT1A8 | ALAS2 | CYTOR | GAS5 | CRBN | TRMU | KDR | ATIC | FFAR1 | Serine/Threonine Kinase (nonspecified subtype) | SLC25A38 | CHRM4 | P4HA3 | TPMT | RRM1 | JAK2 | CFD | GADD45B | G59272 | G7015 | NAT2 | SEC23B | CDA | G7124 | Folate Receptor (nonspecified subtype) | BTK | UGT1A7 | ATP7A | HIF1A | PTK6 | CHRM1 | G3479 | SPTA1 | PMS2 | LAG3 | MMP3 | EIF3A | ACE | GDF2 | CSF3R | FAH | LCK | DCK | ALDH2 | FKBP1A | G1432 | ACVR2A | IL1B | CYP1A1 | P2RY11 | CDO1 | BRCA2 | CD3 Complex (T Cell Receptor Complex) | CYP2C8 | G5133 | GADD45A | IKZF1 | G3569 | IL-3 receptor | CBR1 | EPO | SLC22A16 | DYRK3 | GADD45G | RICTOR | GATA2 | UGT2B7 | HBA2 | HLA-B | PGR | MAP4K4 | HSPA9 | UGT1A9 | CYP24A1 | PKD1L1 | ABCC2 | IMPDH2 | P4HB | MAPK9 | STAT5 (nonspecified subtype) | IL-6 receptor | SLC19A2 | CES1 | CD40 | G581 | Reverse transcriptase (Telomerase) | HK1 | EIF2AK1 | SLC40A1 | TRNT1 | ACVR1 | XRCC3 | ACVRL1 | HBB | KLF1 | ADORA2A | AKR1B1 | LOC105369749 | Heme Oxygenase (HO) (nonspecified subtype) | LOC105378508 | GPR84 | SFTPD | BMP6 | EPOR | MPL | Transforming growth factor beta (nonspecified subtype) | ACHE | G9429 | CYP3A5 | RAD51 | ITPA | FPGS | GRK5 | CES1P1 | HBG2 | HK2 | DNAAF9 | IL12A-AS1 | FGFR4 | SPHK1 | G2099 | FASN | PTPN22 | SFXN4 | CYP2B6 | IFNL4 | MIR126 | EGLN1 | Hypoxia-Inducible Factor Prolyl Hydroxylase (nonspecified subtype) | STEAP3 | G196 | FCGR2A | NOS3 | G4318 | Sterol Regulatory Element-Binding Protein (nonspecified subtype) | C5AR1 | ALDOB | EPHX1 | Complement Complex | SLCO1B1 | GGH | HJV | CDC42 | BMPR1A | SLC31A1 | TYMS | RGMA | APP | alpha-Amylase (nonspecified subtype) | C3 | GAA | KLF12 | G672 | FTO | SLC29A1 | NQO1 | EGLN2 | UGT1A1 | CYP27B1 | MMP2 | ABCC4 | BMPR1B | P4HA2 | PRKCE | REN | SLCO1B3 | GALNT14 | G367 | FANCC | GSTM1 | LCAT | ABL2 | GYPA | TUBB | EPAS1 | FOXP3 | DHFR

疾病靶点研报
Anemia

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