Osteogenesis Imperfecta Type IV

About the Disease
Osteogenesis Imperfecta, Type Iv, also known as osteogenesis imperfecta type iv, is related to osteogenesis imperfecta, type v and osteogenesis imperfecta, type viii. An important gene associated with Osteogenesis Imperfecta, Type Iv is COL1A2 (Collagen Type I Alpha 2 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. The drugs Zoledronic acid and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include bone and eye, and related phenotypes are blue sclerae and scoliosis

Common Targets
COL1A1 | PLOD2 | SPARC | P3H1 | FKBP10 | COL1A2 | IFITM5 | WNT1 | TMEM38B | SERPINF1

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