Disease

Hepatic Steatosis

About the Disease
Fatty Liver Disease, Nonalcoholic 1, also known as nafld1, is related to non-alcoholic fatty liver disease and fatty liver disease. An important gene associated with Fatty Liver Disease, Nonalcoholic 1 is ATG7 (Autophagy Related 7). The drugs Metformin and Entecavir have been mentioned in the context of this disorder. Affiliated tissues include liver, skeletal muscle and kidney, and related phenotype is hepatic steatosis.

Common Targets
GOT2 | HMGCR | PASK | NR1H2 | TYR | NCAN | G23411 | PNPLA3 | PHGDH | Lipoxygenase (nonspecified subtype) | MTNR1A | IL37 | FFAR1 | ADIPOQ | CFD | DGAT1 | Estrogen receptor (nonspecified subtype) | APLNR | HTR2B | IL4R | BSG | TGFBR1 | HDAC3 | IFNL3 | ADORA2B | NR1H3 | MIR34A | DPP4 | CCR2 | HSD11B1 | SCD | XDH | FDFT1 | CD14 | DGAT2 | COL13A1 | IP6K2 | PTPN1 | PPARD | SOD2 | SLC7A11 | PCSK9 | FNDC5 | FGF21 | TXNIP | KHK | NF-kappaB (NFkB) | NR1H4 | HTR2A | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | PDE5A | Oxysterols receptor LXR (nonspecified subtype) | NPY2R | Mitogen-Activated Protein Kinase (nonspecified subtype) | MTNR1B | APOC3 | CYP2E1 | SLC1A5 | BTRC | RBP4 | Histone acetyltransferase (HAT) (nonspecified subtype) | TM6SF2 | GCKR | IAPP | GIPR | FGFR4 | Casein kinase II (CKII) | NEK7 | PSMD9 | Amylin receptor | RORA | IL2 | MERTK | Na+/K+-ATPase (nonspecified subtype) | FASN | PARVB | MAPK9 | ACVR1 | G6PC1 | LEPR | KDM1A | LIPC | ACVRL1 | Complement Complex | LOC157273 | GAA | PCSK7 | AP-1 Transcription Factor Complex | MBOAT7 | ESRRA | PIM1 | LYPLAL1 | TGFB1 | HSD17B13 | G1786 | MTTP | SUCNR1 | SOAT1 | DDIT3 | TPH1 | ACVR1B | MTARC1 | PKM | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | TMC4 | SLC5A1 | GLUD1 | HLA-DPB1 | AGER | ENPP1 | FTO | ACMSD | ALOX5 | IL13 | GLP1R | P2RX7 | SGMS2 | MAPK10 | ADIPOR2 | DENND5B | HK2 | IFNL4 | APOB | NQO1 | DNA topoisomerase (nonspecified subtype) | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | AMP-activated protein kinase (AMPK) | TGFBR2 | ESRRG | PDGFRB | CSF1R | DAGLA | STK25 | CMKLR1 | LOC101929713 | HIF1A | KLF6 | G2475 | Sterol Regulatory Element-Binding Protein (nonspecified subtype) | ACLY | G595 | BMPR1A | G4780 | SLC43A1 | CALCR | Cytochrome P450 4A (nonspecified subtype) | SOAT2 | ACACA | CSNK1D | ESD | MTHFR | SLC38A8 | CYP4A11 | PPARGC1A | SIRT3 | TBK1 | IRS1 | CRACR2A | PPARG | LBP | Sphingomyelin synthase (nonspecified subtype) | G1956 | MCHR1 | RELN | IKBKE | LDLR | PPARA | DAGLB | MBOAT4 | Calcium channel (nonspecified subtype) | GCGR | SLC5A2 | BMPR1B | UCP2 | GPBAR1 | IP6K1 | Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) | COX1 | SIRT6 | CNR1 | NR2F6 | ND6 | G2099 | LPIN1 | Acetyl-CoA Carboxylases (ACC) (nonspecified subtype) | SAMM50 | G5599 | G5743 | FFAR4 | SREBF1 | ELOVL6 | MAP2K4 | CSNK1E | SLC2A5 | TTR | BRD4 | ESR2 | ACHE | PTGS1 | G3569 | Tyrosine-Protein Kinases Src (nonspecified subtype) | MYLIP | THRB | CMKLR2 | G4233 | EHBP1L1 | Diacylglycerol Acyltransferase (DGAT) (nonspecified subtype) | G7124 | G3630

疾病靶点研报
Hepatic Steatosis

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