Disease

Hereditary Sensory And Autonomic Neuropathy

About the Disease
Hereditary Sensory Neuropathy, also known as hereditary sensory and autonomic neuropathy, is related to insensitivity to pain, congenital, with anhidrosis and neuropathy, hereditary sensory and autonomic, type i, with cough and gastroesophageal reflux. An important gene associated with Hereditary Sensory Neuropathy is SPTLC1 (Serine Palmitoyltransferase Long Chain Base Subunit 1), and among its related pathways/superpathways are Neuroscience and Signaling by NTRKs. The drugs Folic acid and Lipoic acid have been mentioned in the context of this disorder. Affiliated tissues include tongue, spinal cord and tonsil, and related phenotypes are growth/size/body region and nervous system

Common Targets
DST | RETREG1 | SPTLC2 | MPZ | IQGAP3 | SCN11A | SPTLC1 | WNK1 | CLCN5 | ATL3 | KIF1A

疾病靶点研报
Hereditary Sensory And Autonomic Neuropathy

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