Epidermolysis Bullosa

About the Disease
Epidermolysis Bullosa, also known as acantholysis bullosa, is related to epidermolysis bullosa simplex 1b, generalized intermediate and epidermolysis bullosa, junctional 1b, severe. An important gene associated with Epidermolysis Bullosa is KRT5 (Keratin 5), and among its related pathways/superpathways are ERK Signaling and Integrin Pathway. The drugs Morphine and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include skin, bone marrow and bone, and related phenotypes are growth/size/body region and immune system

Common Targets
DST | AMP-activated protein kinase (AMPK) | CNR2 | PLEC | TRPM8 | CHRNE | LAMB2 | CNR1 | EXPH5 | ITGA3 | KRT5 | LAMB3 | TRPV2 | TRPV1 | GZMB | MMP7 | COL17A1 | LAMC2 | DSP | KRT14 | MMP2 | TRPA1 | TACR1 | AGTR1 | PKP1 | CASP1 | LAMA3 | NLRP3 Inflammasome | IL1B | FERMT1 | ITGB4 | CD151 | ANPEP | G114548 | Collagen (nonspecified subtype) | GPR55 | MMP1 | COL7A1 | ITGA6

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