Disease

Epidermolysis Bullosa

About the Disease
Epidermolysis Bullosa, also known as acantholysis bullosa, is related to epidermolysis bullosa simplex 1b, generalized intermediate and epidermolysis bullosa, junctional 1b, severe. An important gene associated with Epidermolysis Bullosa is KRT5 (Keratin 5), and among its related pathways/superpathways are ERK Signaling and Integrin Pathway. The drugs Morphine and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include skin, bone marrow and bone, and related phenotypes are growth/size/body region and immune system

Common Targets
DST | AMP-activated protein kinase (AMPK) | CNR2 | PLEC | TRPM8 | CHRNE | LAMB2 | CNR1 | EXPH5 | ITGA3 | KRT5 | LAMB3 | TRPV2 | TRPV1 | GZMB | MMP7 | COL17A1 | LAMC2 | DSP | KRT14 | MMP2 | TRPA1 | TACR1 | AGTR1 | PKP1 | CASP1 | LAMA3 | NLRP3 Inflammasome | IL1B | FERMT1 | ITGB4 | CD151 | ANPEP | G114548 | Collagen (nonspecified subtype) | GPR55 | MMP1 | COL7A1 | ITGA6

疾病靶点研报
Epidermolysis bullosa

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Granuloma Annulare | Charcot-Marie-Tooth Disease Type 2D | Multiple Sclerosis, Primary Progressive | Transient Bullous Dermolysis Of The Newborn | Uveitis, Anterior | Hypertrophy | Epidermolytic Hyperkeratosis | Basal Ganglia Disease | 3C Syndrome | Osteogenesis Imperfecta Type VI | Cushing Syndrome | Osteogenesis Imperfecta Type III | Glutaric Aciduria Type 2 | Spinocerebellar Ataxia Type 16 | Infantile Nephropathic Cystinosis | Hypersensitivity | Becker Muscular Dystrophy | Acute Leukemia | Holt-Oram Syndrome | Congenital Tufting Enteropathy | Myasthenia Gravis | Periodontitis | Ocular Albinism Type 1 | Echinococcosis | Scleritis | Emery-Dreifuss Muscular Dystrophy | Sjogren Syndrome | Vitamin D Deficiency | Sleep Apnea, Central | Choriocarcinoma | Fascioliasis | Erythema Multiforme | Mucolipidosis | Endophthalmitis | Blue Rubber Bleb Nevus Syndrome | SAPHO Syndrome | Chronic Idiopathic Myelofibrosis | Coffin-Siris Syndrome | Spastic Paraplegia Type 7 | Evans Syndrome | Lentigo | 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