Disease

Inborn Errors Of Metabolism

About the Disease
Inherited Metabolic Disorder, also known as inborn errors of metabolism, is related to phenylketonuria and carbohydrate metabolic disorder. An important gene associated with Inherited Metabolic Disorder is TKFC (Triokinase And FMN Cyclase), and among its related pathways/superpathways are Cell differentiation - expanded index and Interactions between immune cells and microRNAs in tumor microenvironment. The drugs Bezafibrate and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, liver and t cells.

Common Targets
GALNS | CAD | SLC6A8 | GLYCTK | ABCD4 | SPR | HSD11B1 | IVD | ACSF3 | UGCG | TSFM | HSD17B10 | ACADVL | HPD | PKLR | ALDH3A1 | ARSB | MMADHC | HADHA | MMACHC | NR1H4 | IKBKG | Chaperone (nonspecified subtype) | FBXL4 | APOC3 | CYP2C8 | NDUFS1 | Alcohol Dehydrogenase (nonspecified subtype) | GFM1 | ADA | AKR1D1 | TTC19 | NAXE | SLC13A5 | GLS | Adenosine deaminase (nonspecified subtype) | SLC16A1 | GAMT | LMBRD1 | ASL | HIBCH | SUCLA2 | PRF1 | FUCA1 | Histone deacetylase (nonspecified subtype) | MTHFD1 | SLC10A1 | CYP7B1 | GAA | HEXA | ACAT1 | Pyruvate dehydrogenase kinase (nonspecified subtype) | TRNA | HMGCS2 | H6PD | PNP | UGT1A1 | FUCA2 | HEXB | NAGA | CYP19A1 | P2X Receptor (nonspecified subtype) | ACY1 | SLC5A1 | OGA | TH | FBP1 | GPI | Cytochrome P450 Enzymes (nonspecified subtype) | APOB | DHFR | RMND1 | GLB1 | SLC22A5 | TALDO1 | G6PD | CYP27A1 | PCK1 | SURF1 | ND5 | MTHFR | FMO3 | ABCC3 | UROC1 | TNFRSF9 | ETHE1 | BCAT2 | BTD | G5243 | MC1R | MRTFA | NDUFA6 | PGK1 | HSD3B2 | GPBAR1 | ETFDH | GLA | Na+/Ca2+ Exchanger (NCX) (nonspecified subtype) | NPC2 | SLC25A20 | RFT1 | FTCD | G9429 | DIPK2B | ADK | IDUA | UPB1 | GBA1 | ZNF143 | ECHS1

疾病靶点研报
Inborn Errors Of Metabolism

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