Familial Male-limited Precocious Puberty

About the Disease
Precocious Puberty, Male-Limited, also known as testotoxicosis, is related to precocious puberty, central, 1 and cortisone reductase deficiency. An important gene associated with Precocious Puberty, Male-Limited is LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Megestrol acetate and Leuprolide have been mentioned in the context of this disorder. Affiliated tissues include testes, testis and bone, and related phenotypes are precocious puberty and tall stature

Common Targets
LHCGR

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