Optic Neuropathy

About the Disease
Optic Nerve Disease, also known as optic neuropathy, is related to leber optic atrophy and dystonia and toxic optic neuropathy, and has symptoms including eye manifestations and sciatica. An important gene associated with Optic Nerve Disease is TYR (Tyrosinase), and among its related pathways/superpathways are Metabolism and "Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.". The drugs Dalfampridine and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include optic nerve, eye and retina, and related phenotype is vision/eye.

Common Targets
MAP3K12 | RTN4IP1 | ROCK1 | ND1 | cAMP-Dependent protein kinase (PKA) | MAP3K13 | AARS2 | TULP1 | ACO2 | CASP2 | MFN2 | SPG7 | ROCK2 | KARS1 | ATP6 | OPA1 | Rho kinase (ROCK) (nonspecified subtype) | Soluble guanylyl cyclase | MCAT | GPR17 | G5728 | ND6

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