Disease

Postmenopausal Osteoporosis

About the Disease
Osteoporosis, also known as postmenopausal osteoporosis, is related to osteoporosis, juvenile and bone mineral density quantitative trait locus 15, and has symptoms including angina pectoris, back pain and muscle cramp. An important gene associated with Osteoporosis is COL1A1 (Collagen Type I Alpha 1 Chain), and among its related pathways/superpathways are Breast cancer pathway and Vitamin D receptor pathway. The drugs Clobetasol and Hydrocortisone have been mentioned in the context of this disorder. Affiliated tissues include Bone, and related phenotypes are osteoporosis and homeostasis/metabolism

Common Targets
FGF2 | FLT3 | MIR149 | MST1R | TNFRSF11B | PMVK | CCN1 | FOXF1 | CRBN | LOC101448202 | SOST | CDK5/p25 | NR3C2 | RDX | COL1A1 | FDFT1 | VKORC1 | G7124 | HDAC5 | MMP3 | AXL | ACE | LRP5 | MVD | IDI2 | ARID4B | GH1 | CASR | CDK5 | ENG | PPID | COL5A1 | TNFSF11 | CD86 | MVK | PGR | HLA-B | Estrogen receptor (nonspecified subtype) | NPY | CCR2 | SQOR | LCT | COL1A2 | ADIPOR1 | ACVRL1 | FDPS | DYNC2H1 | MERTK | STS | TNFRSF11A | Elastase (nonspecified subtype) | GHR | Transforming growth factor beta (nonspecified subtype) | SOX9 | PTPN4 | TYRO3 | PER1 | ADIPOR2 | G2099 | MCM6 | PTH1R | IDI2-AS1 | CTSK | NPR1 | GGPS1 | G4318 | CALCR | Parathyroid Hormone Receptors (PTHR) (nonspecified subtype) | G367 | G4233 | CCL2 | VDR | PI3

疾病靶点研报
Postmenopausal Osteoporosis

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