Martsolf Syndrome

About the Disease
Martsolf Syndrome 1, also known as martsolf syndrome, is related to rab18 deficiency and warburg micro syndrome 2, and has symptoms including finger joint laxity An important gene associated with Martsolf Syndrome 1 is RAB3GAP2 (RAB3 GTPase Activating Non-Catalytic Protein Subunit 2), and among its related pathways/superpathways are Vesicle-mediated transport and COPI-independent Golgi-to-ER retrograde traffic. Affiliated tissues include eye, tongue and trachea, and related phenotypes are intellectual disability and cataract

Common Targets
RAB3GAP2 | ITPA | RAB3GAP1 | TBC1D20

Note: If you'd like to get a target analysis report for Martsolf Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Martsolf Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Myocardial Infarction | Fibromyalgia | Lupus Erythematosus | Mycosis Fungoides | Congenital Nephrotic Syndrome | Glycogen Storage Disease Type 5 | Scapuloperoneal Myopathy, X-linked Dominant | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Spastic Paraplegia Type 7 | H Syndrome | Branchiootorenal Syndrome | Spinocerebellar Ataxia Type 15 | Prolymphocytic Leukemia | Hyperbilirubinemia | Optic Nerve Diseases | Spondylometaphyseal Dysplasia | McLeod Syndrome | Succinic Semialdehyde Dehydrogenase Deficiency | Oligoastrocytoma | Congenital Fiber-type Disproportion Myopathy | Takayasu's Arteritis | Meier-Gorlin Syndrome | Megalencephaly | Charcot-Marie-Tooth Disease Axonal Type 2N | Lymphoma, Follicular | Plasma Cell Leukemia | Tonsillitis | Usher Syndrome Type II | Hypertension, Renal | Keratosis, Seborrheic | Maple Syrup Urine Disease | Bietti Crystalline Dystrophy | Macular Corneal Dystrophy | Antithrombin III Deficiency | Amyotrophic Lateral Sclerosis, Juvenile | Cartilage Disorders | Juvenile Myelomonocytic Leukemia | Mitochondrial DNA Depletion Syndrome | Uremia | Hemosiderosis | Heterotaxy | Chromosome 8q21.11 Deletion Syndrome | Antley-Bixler Syndrome | Nasodigitoacoustic Syndrome | Ovarian Sex Cord-stromal Tumor | Congenital Poikiloderma | Gray Platelet Syndrome | Mitochondrial Disease | ICF Syndrome | Renal Dysplasia | Primary Erythromelalgia | Atelosteogenesis Type 1 | Peutz-Jeghers Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Gingivitis | Lymphoma Lymphoblastic | Unverricht-Lundborg Syndrome | Costello Syndrome | Temporal Lobe Epilepsy | Poirier-Bienvenu Neurodevelopmental Syndrome | Carcinoma In Situ | Facioscapulohumeral Muscular Dystrophy | Iron Deficiency Anemia | Cardiomyopathy, Hypertrophic | Nance-Horan Syndrome | Chronic Kidney Disease | Meningococcal Meningitis | Autonomic Nervous System Disorders | Primary Ovarian Insufficiency | COACH Syndrome | Intestinal Obstruction | Nestor-Guillermo Progeria Syndrome | Early Infantile Epileptic Encephalopathy 1 | Parvovirus B19 Infection | Hereditary Mixed Polyposis Syndrome | Open-angle Glaucoma | Encephalopathy, Glycine | Van Der Knaap Disease | Leukodystrophies | Hypermethioninemia | Cystitis, Interstitial | Charcot-Marie-Tooth Disease, Type 2C | Farber Disease | Oligoasthenoteratozoospermia | Sialoadenitis | Diabetic Nephropathy | Gangliosidosis | Congenital Aniridia | Facioscapulohumeral Muscular Dystrophy Type 2 | Diabetes | Sarcoma | Glutaric Aciduria Type 3 | Retinal Diseases | Pericarditis | Carcinoma, Small Cell | Pemphigoid | Urethritis | Blood Protein Disorders | Odonto-onycho-dermal Dysplasia | Thyrotoxic Periodic Paralysis | Distal Spinal Muscular Atrophy | Metachondromatosis | Kabuki Syndrome | Fanconi Syndrome | Lymphoma, Mantle Cell | Acute Myeloid Leukemia | Insulinoma | Rhabdoid Tumor | Adrenal Insufficiency | Rett Syndrome | Fetal Alcohol Syndrome | Congenital Torticollis | Colitis, Collagenous | Xeroderma Pigmentosum | Mitochondrial Cytopathy | Esophagitis | Myeloid Leukemia | Bruck Syndrome | Moyamoya Disease | Placenta Previa | Cholestasis | Colorectal Adenoma | Granular Corneal Dystrophy | Spinal And Bulbar Muscular Atrophy | LEOPARD Syndrome | Rolandic Epilepsy | Amebiasis | Frontometaphyseal Dysplasia | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | CHARGE Syndrome | Keratoconjunctivitis | Ventricular Septal Defect | Impulse Control Disorder | Micropenis | Follicular Dendritic Cell Sarcoma | Genee-Wiedemann Syndrome | Bone Marrow Necrosis | Tinea Versicolor | Pyruvate Carboxylase Deficiency Disease | Actinomycetoma | Myofibromatosis | Multiple Sclerosis, Chronic Progressive | Sengers Syndrome | Proctitis | Ectopia Lentis, Isolated, Autosomal Recessive | Paroxysmal Nocturnal Hemoglobinuria | Measles | Neural Tube Defect | Primary Hyperoxaluria Type 3 | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Creutzfeldt-Jakob Disease | Ichthyosis Hystrix, Curth-Macklin Type | Corneal Neovascularization | Jacobsen Syndrome | Pontocerebellar Hypoplasia Type 2 | Paroxysmal Kinesigenic Dyskinesia | Macrodactyly | Cutaneous T-cell Lymphoma | Pre-eclampsia | Usher Syndrome Type IIC | Hypertriglyceridemia | Osteogenesis Imperfecta Type III | Headache | Chorea-acanthocytosis | Hepatitis, Autoimmune | Pituitary Stalk Interruption Syndrome | Spinocerebellar Ataxia Type 42 | Neurocysticercosis | Purpura | Ichthyosis, X-linked | Arthrogryposis | Skin Papilloma | Ischemia | Spinocerebellar Ataxia Type 16 | Angioedema, Acquired | Anorexia Nervosa | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Congenital Hereditary Endothelial Dystrophy Type II | Epidermolysis Bullosa Simplex, Localized | Blepharophimosis Syndrome | Osteoporosis | Early Infantile Epileptic Encephalopathy 13 | Rhinitis | Sarcoma, Alveolar Soft Part | Pleomorphic Xanthoastrocytoma | Motor Neuron Diseases | Chondrodysplasia Punctata 1, X-linked Recessive | Lymphoma, AIDS-related | Diffuse Palmoplantar Keratoderma | Pearson Syndrome | Glutaric Aciduria Type 2 | Adenoma, Pituitary | Veno-occlusive Disease | Blastomycosis | Hyper IgE Syndrome | Vaginitis | Sarcomatoid Carcinoma Of The Lung | Primary Carnitine Deficiency | Pleurisy | Dermatomyositis | Peripheral T-cell Lymphoma | Epidermolytic Hyperkeratosis | Cancer, Breast | Cerebellofaciodental Syndrome | Thrombocytopenia | Macrophage Activation Syndrome | Persistent Hyperplastic Primary Vitreous | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Deafness, Dystonia, And Cerebral Hypomyelination | Exfoliative Dermatitis | Hamartoma | Familial Hypobetalipoproteinemia | Guttate Psoriasis | Rosacea | Bronchitis | Marshall-Smith Syndrome | Pyruvate Decarboxylase Deficiency | Bronchitis, Chronic | Cardiomyopathy, Restrictive | Vitelliform Macular Dystrophy | Skin Carcinoma | Apparent Mineralocorticoid Excess Syndrome | Charcot-Marie-Tooth Disease, Type 2A | Sclerosteosis 2 | Aldosterone Synthase Deficiency | Thrombophilia | Analgesia | Depression | Behavioral Variant Of Frontotemporal Dementia | Cheilitis | Parapsoriasis | Nicolaides-Baraitser Syndrome | Infantile Refsum Disease | Mesothelioma, Malignant | Chondroma | Birt-Hogg-Dube Syndrome | Spinocerebellar Ataxia Type 14 | Chediak-Higashi Syndrome | Keloid | Hypolipoproteinemia | Scabies | X-linked Creatine Transporter Deficiency | Gastroschisis | Congenital Nystagmus | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Wiskott-Aldrich Syndrome | Otitis Media | Strabismus | Venous Insufficiency | Otosclerosis | Ichthyosis | Cholesteryl Ester Storage Disease | Lymphopenia | Extramammary Paget's Disease | Cancer, Lung | Dysgerminoma | Diffuse Mesangial Sclerosis | Methylmalonic Acidemia | Lipid Metabolism Disorders | Granuloma Annulare | Presbycusis | Intermittent Claudication | Vitamin A Deficiency | Omenn Syndrome | Hypotension, Orthostatic | Chronic Granulomatous Disease, X-linked | Chudley-McCullough Syndrome | Carbamoyl Phosphate Synthetase I Deficiency | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Echinococcosis | Pontocerebellar Hypoplasia Type 7 | Autoimmune Disease | Autosomal Recessive Bestrophinopathy | Hypocalcemia | Uremic Pruritus | Spinocerebellar Ataxia Type 2 | Pseudoexfoliation Syndrome | Esophagitis, Eosinophilic | Leber Congenital Amaurosis | Coloboma | Wolfram Syndrome 2 | Pure Red Cell Aplasia | Herpes Simplex Dermatitis | Ophthalmia, Sympathetic | Cleidocranial Dysplasia | Coronary Restenosis | Dysmorphophobia | Pseudohermaphroditism | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Diamond-Blackfan Anemia | Hyperinsulinemic Hypoglycemia | Cherubism | Phenylketonuria II | Frontotemporal Dementia | Glycogen Storage Disease Type 3 | Cerebellar Ataxia, Cayman Type | Metatropic Dysplasia | Retinitis Pigmentosa 3 | Otopalatodigital Syndrome Type 2 | Anterior Segment Dysgenesis | Myhre Syndrome | Paraplegia | Renal-hepatic-pancreatic Dysplasia | Osteoporosis, Postmenopausal | Argininosuccinic Aciduria | Delayed Sleep Phase Syndrome | Schuurs-Hoeijmakers Syndrome | Bicuspid Aortic Valve | Systemic Mastocytosis | Glycogen Storage Disease Type 0 | Premenstrual Syndrome | Shprintzen-Goldberg Syndrome | Chromosome 9q34.3 Deletion Syndrome | Hypertension, Pulmonary | Iron Metabolism Disorders | Neuroblastoma | Axenfeld-Rieger Syndrome | Episodic Ataxia Type 1 | Angioedema | Camurati-Engelmann Disease | Diverticulitis | Sarcoidosis, Pulmonary | Arthritis, Psoriatic | Retinitis Pigmentosa | Spondyloperipheral Dysplasia | Kleine-Levin Syndrome | Melanocytic Nevus | Hyperlipidemia Type V | Corneal Edema | Heart Failure | Hypospadias | Bare Lymphocyte Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Hemoglobinopathies | Hyperhomocysteinemia | Hereditary Xerocytosis | Lafora Disease | Cockayne Syndrome | Spondyloarthritis | Dengue Shock Syndrome | Enhanced S-cone Syndrome | Heroin Dependence | Pelvic Inflammatory Disease | Tay-Sachs Disease | Multiple Sclerosis, Primary Progressive | Alopecia | Communication Disorders | Ollier Disease | Gilbert Syndrome | Peyronie's Disease | Intermittent Explosive Disorder | Blastoma, Pleuropulmonary | Parkinson's Disease | Asthma | Leukoencephalopathy, Progressive Multifocal | Cirrhosis | Retinal Detachment | Kaposiform Hemangioendothelioma | Androgen Insensitivity | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Hidradenitis Suppurativa | Cardiomyopathy, Peripartum | Acrocallosal Syndrome | Benign Familial Neonatal Convulsions | Hepatitis E | Trichomegaly | Lymphoma, B-cell | Cryoglobulinemia | Eiken Syndrome | Congenital Myopathy | Neuromuscular Disorders | Congenital Heart Block | Chondrosarcoma | Coronary Heart Disease | Generalized Epilepsy With Febrile Seizures Plus | Interstitial Lung Diseases | Lysosomal Acid Lipase Deficiency | Wagner Disease | Conn Syndrome | X-linked Acrogigantism | Cardiac Sarcoidosis | Crouzon Syndrome With Acanthosis Nigricans | Hyperparathyroidism | Neurodermatitis | Bloom Syndrome | Hypodontia | Dent Disease | Epidermolysis Bullosa Simplex, Generalized | Schistosomiasis | Meningococcal Infections | Progressive Osseous Heteroplasia | Situs Inversus | VACTERL Association | Hydrocephalus | Muscular Dystrophy | Congenital Generalized Lipodystrophy | L-2-Hydroxyglutaric Aciduria | Cataract | Anti-glomerular Basement Membrane Disease | Neutrophilia