Hidradenitis Suppurativa

About the Disease
Hidradenitis Suppurativa, also known as acne inversa, is related to dowling-degos disease and inflammatory bowel disease 1, and has symptoms including painful nodules, exanthema and pruritus. An important gene associated with Hidradenitis Suppurativa is NCSTN (Nicastrin), and among its related pathways/superpathways are ERK Signaling and Disease. The drugs Triamcinolone and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and lymph node, and related phenotypes are no effect and no effect

Common Targets
MIR548I3 | MIR548H5 | DTX2 | MIR548I4 | MIR548F1 | PSEN1 | MIR200A | MIR1306 | IL2RA | MIR132 | TLR10 | IL23A | MIR1280 | DTX4 | MIR1266 | MIR548I1 | LYST | C5 | MIR2110 | MIR320A | G1950 | MIR943 | MIR200B | MIR33B | ELOVL7 | IL17RA | FAT4 | MIR1180 | MIR153-2 | NR3C1 | MIR200C | MIR933 | MFNG | MIR410 | MIR941-3 | MIR1178 | HDAC1 | MIR548L | MIR548I2 | MIR548A1 | MIR1237 | APH1B | PHTF1 | MIR548A2 | MIR548A3 | MIR548B | MIR548C | MIR548D1 | MIR548H3 | MIR548D2 | MIR549A | MIR548P | NOD2 | MIR556 | IL-1 Receptor (nonspecified subtype) | MIR557 | MIR568 | MIR205 | ADAM17 | MIR575 | MIR138-1 | MIR138-2 | MIR581 | SYK | LRRC8B | MAP3K14 | CXCR1 | CD40 | G3605 | MIR590 | MIR591 | MIR592 | NLE1 | SEC24B | NFKBIA | MIR548K | MIR548F2 | TLR2 | G367 | MIR548O | MIR548H1 | MIR143 | IRAK4 | MIR548Q | MIR548H4 | MIR2116 | MIR519C | MIR548J | Interleukin-12 (IL-12) | PLXND1 | MIR548G | NOTCH2NLA | CHD1L | MAPKAPK2 | TMEM191A | BMP2K | IL1B | FLT3 | MIR26A2 | IL1R1 | IL1A | MIR340 | PRAG1 | MIR369 | MAML2 | MIR192 | MIR617 | MIR373 | CSF2 | CDKN1B | ZFYVE28 | CXCR2 | JAK2 | MIR211 | ZNF423 | MEFV | MIR629 | IL12A | JAK1 | CREBBP | MIR639 | MIR194-2 | MIR539 | CUL2 | MIR487B | IL1RL2 | MIR216A | MIR29A | C5AR1 | NOTCH2 | ATOSB | MIR125B1 | G7124 | ELF3 | TLR6 | SEL1L | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | MIR93 | TGFB1 | PSENEN | MIR29B1 | NCSTN | MIR656 | LTA4H | IL18 | EPN1 | MIR658 | MIR9-3 | G7099 | MIR29B2 | KRT19 | Interleukin 23 complex (IL-23) | MAGEA1 | TLR1 | MIR499A | RORC | ROBO2 | MIR29C | MIR218-2 | MIR548N | Defensin (nonspecified subtype) | MIRLET7A1 | IL12B | Phosphodiesterase IV (PDE4) (nonspecified subtype) | MIRLET7A2 | IL1RN | MIRLET7A3 | ATP11A | DCPS | Interleukin 17 (nonspecified subtype) | MIR219A2 | IFT172 | GOT1 | METTL3 | NOTCH3

Note: If you'd like to get a target analysis report for Hidradenitis Suppurativa, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hidradenitis Suppurativa at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Aicardi-Goutieres Syndrome | Neuroblastoma | Sialidosis | Pathological Gambling | Autoimmune Disease | Thyroid Hormone Resistance | Androgenic Alopecia | Pancytopenia | Chronic Thromboembolic Pulmonary Hypertension | Spinocerebellar Ataxia Type 15 | Colitis, Collagenous | Thrombocytopenia | Neurocysticercosis | Warsaw Breakage Syndrome | Cornelia De Lange Syndrome | Bicuspid Aortic Valve | Arthritis, Reactive | GLUT1 Deficiency Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Meningitis | Methylmalonic Aciduria And Homocystinuria, CblC Type | Oculocutaneous Albinism | 3-methylglutaconic Aciduria Type I | Astigmatism | Trichuriasis | Esophageal Motility Disorders | Hypohidrotic Ectodermal Dysplasia | Schnyder Crystalline Corneal Dystrophy | Spinocerebellar Ataxia | Atopic Dermatitis | Congenital Tufting Enteropathy | Antisocial Personality Disorder | Lipid Metabolism Disorders | Panuveitis | Neurotoxicity | Pulmonary Stenosis | Congenital Stromal Corneal Dystrophy | Sleep Disorder | Acrocallosal Syndrome | Sezary Syndrome | Mood Disorder | Congenital Adrenal Hyperplasia 1 | Dysferlinopathy | Acute Tubular Necrosis | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Basal Ganglia Disease | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Diffuse Intrinsic Pontine Glioma | Trichothiodystrophy | Riboflavin Transporter Deficiency Neuronopathy | Dowling-Degos Disease | Creutzfeldt-Jakob Disease | Heart Failure | Hoyeraal-Hreidarsson Syndrome | Coloboma | Niemann-Pick Disease, Type B | Peroxisomal Disorder | Gingivitis | Gangliosidosis | Alagille Syndrome | Panic Disorder | Pulmonary Veno-occlusive Disease | Localized Scleroderma | Nicolaides-Baraitser Syndrome | T-cell Prolymphocytic Leukemia | C3 Glomerulonephritis | Frontotemporal Dementia | Metachromatic Leukodystrophy | Rhizomelic Chondrodysplasia Punctata | Myotonia | Behcet's Disease | Charcot-Marie-Tooth Disease, Type 1A | Chronic Kidney Disease | Mastitis | Extramammary Paget's Disease | Primary Pigmented Nodular Adrenocortical Disease | Thyrotoxic Periodic Paralysis | Sclerosteosis 2 | Antithrombin III Deficiency | Hypermethioninemia | Cholera | Lateral Meningocele Syndrome | Renal Tubular Dysgenesis | Congenital Hereditary Endothelial Dystrophy Type II | Meningococcal Meningitis | Cat Eye Syndrome | Granular Corneal Dystrophy | Cutis Laxa | Urofacial Syndrome | Keratosis, Seborrheic | Delayed Sleep Phase Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | Primary Hyperoxaluria Type 1 | Bronchiectasis | Partington Syndrome | Gardner Syndrome | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Aldosterone Deficiency | Insulinoma | Atelosteogenesis Type 1 | Neurodegeneration With Brain Iron Accumulation | Leukoencephalopathy, Progressive Multifocal | Nephrosclerosis | Waardenburg Syndrome | Knobloch Syndrome | Kernicterus | Renpenning Syndrome | Sulfite Oxidase Deficiency | Fundus Albipunctatus | Celiac Disease | Impetigo | Myelodysplasia | Benign Familial Infantile Seizures | Parapsoriasis | Vogt-Koyanagi-Harada Syndrome | Wiedemann-Steiner Syndrome | Lennox-Gastaut Syndrome | Spinocerebellar Ataxia Type 31 | Fibrosis | Corneal Edema | Leiomyosarcoma | Astrocytoma | Headache | Fabry's Disease | Posterior Polar Cataract | Waardenburg Syndrome Type 2 | Hyperthermia, Malignant | Glutathione Synthetase Deficiency | Myeloid Leukemia | Tyrosine Hydroxylase Deficiency | Hyperhomocysteinemia | Lymphoproliferative Disease, X-linked | Multiple Epiphyseal Dysplasia | Seminoma | Hemophagocytic Lymphohistiocytosis | Neurodevelopmental Disorders | Distal Spinal Muscular Atrophy | Pycnodysostosis | Schizencephaly | Allergic Contact Dermatitis | Carney-Stratakis Syndrome | Encephalitis, Tick-borne | Dwarfism | Malignant Fibrous Histiocytoma | Chorioretinitis | Reticular Dysgenesis | Diffuse Palmoplantar Keratoderma | Myositis | Dent Disease | Cantu Syndrome | Carcinoma In Situ | Hyperglycemia | Gliosarcoma | Hennekam Lymphangiectasia-lymphedema Syndrome | Colorectal Adenoma | Miyoshi Myopathy | Basal Ganglia Disease, Biotin-responsive | Trigonocephaly | Polycystic Ovary Syndrome | Fascioliasis | Galloway-Mowat Syndrome | Melanoma, Malignant | Thyroiditis, Autoimmune | Gynecomastia | Loeys-Dietz Syndrome Type 4 | Osteogenesis Imperfecta Type IV | Nail Disorder, Nonsyndromic Congenital | Arteriovenous Malformations | Schizophrenia, Paranoid | Myoclonic Epilepsy With Ragged Red Fibers | Glycogen Storage Disease Type 6 | Cancer, Prostate | Prader-Willi Syndrome | Systemic Mastocytosis | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Sarcoma, Ewing | Progressive External Ophthalmoplegia | Silver-Russell Syndrome | Hypersensitivity | Chanarin-Dorfman Syndrome | Inflammatory Joint Disease | CREST Syndrome | Dental Caries | Paracoccidioidomycosis | Delirium | Ocular Hypertension | Erythematotelangiectatic Rosacea | L-2-Hydroxyglutaric Aciduria | Ichthyosis Bullosa Of Siemens | Spinocerebellar Ataxia Type 14 | Diastrophic Dysplasia | Chordoid Glioma | Campomelic Dysplasia | Bloom Syndrome | Schizoaffective Disorder | Hypokalemia | Basan Syndrome | Chromosome 9q34.3 Deletion Syndrome | Myasthenia Gravis | Osteoglophonic Dysplasia | Arterial Tortuosity Syndrome | Esthesioneuroblastoma | Neovascular Glaucoma | Hemangioendothelioma | Stroke, Ischemic | Chronic Periodontitis | Chiari Malformation Type I | Reflex Epilepsy | Personality Disorders | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Pyruvate Kinase Deficiency | Sengers Syndrome | Congenital Myopathy | Familial Thoracic Aortic Aneurysm | Trismus-pseudocamptodactyly Syndrome | Cancer, Colon | Hepatitis | Retinal Coloboma | Chromosome 17q21.31 Deletion Syndrome | Open-angle Glaucoma | Lymphoma Lymphoblastic | Keratosis, Actinic | Glutaric Aciduria Type 3 | Spinocerebellar Ataxia Type 3 | Osteomalacia | Dementia | Hyperuricemic Nephropathy, Familial Juvenile | Pulmonary Tuberculosis | Tardive Dyskinesia | Palmoplantar Keratoderma | Otopalatodigital Syndrome Type 2 | Hyper IgE Syndrome | Neutrophilia | Smoldering Myeloma | Leukodystrophies | Corneal Ulcer | Carcinoma, Squamous Cell | Ectrodactyly | Bare Lymphocyte Syndrome | Alcoholism | Osteogenesis Imperfecta Type II | Martsolf Syndrome | Epilepsy Of Infancy With Migrating Focal Seizures | Cardiomyopathy, Restrictive | Schwannomatosis | Thromboembolism | Nanophthalmos | Acromegaly | Epidermolytic Hyperkeratosis | Oculopharyngeal Muscular Dystrophy | Portal Vein Thrombosis | Syphilis | Noonan Syndrome-like Disorder With Loose Anagen Hair | Smith-Kingsmore Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Non-Langerhans Cell Histiocytosis | Coronary Artery Disease | Leukemia | Progressive Familial Intrahepatic Cholestasis | Iron Deficiency Anemia | Acute Lymphocytic Leukemia | Fukuyama Congenital Muscular Dystrophy | Pelvic Inflammatory Disease | Congenital Nystagmus | Measles | Spitz Nevus | Usher Syndrome Type I | Birk-Barel Syndrome | Nephrocalcinosis | Rothmund-Thomson Syndrome | Hypertension, Pulmonary | Psoriasis | Chondrosarcoma | Fahr Disease | Pityriasis Rubra Pilaris | Prolidase Deficiency | Intestinal Tuberculosis | Ichthyosis Hystrix, Curth-Macklin Type | Spinocerebellar Ataxia Type 5 | Infantile Spasm | Pseudohypoparathyroidism Type 2 | Muckle-Wells Syndrome | Cholesteryl Ester Storage Disease | Methylmalonic Acidemia | Heterotopic Ossification | Presbyopia | Patent Foramen Ovale | Renal-hepatic-pancreatic Dysplasia | Schwartz-Jampel-Aberfeld Syndrome | Epilepsy | Hyperinsulinism-hyperammonemia Syndrome | Kleine-Levin Syndrome | Coma | Juvenile Xanthogranuloma | Nephroblastoma | Acne | Benign Familial Neonatal Convulsions | Temporal Lobe Epilepsy | Language Disorders | Alpha-1 Antitrypsin Deficiency | Apert Syndrome | Primary Carnitine Deficiency | Pseudohypoaldosteronism | Neurofibromatosis | Blepharo-cheilo-odontic Syndrome | Ocular Albinism Type 1 | Polymyalgia Rheumatica | Meconium Ileus | Familial Partial Lipodystrophy | Facioscapulohumeral Muscular Dystrophy | Compartment Syndrome | Bulimia Nervosa | Strabismus | Uremia | Sarcoma, Endometrial Stromal | Dermatitis Herpetiformis | Familial Isolated Hyperparathyroidism | Progressive Osseous Heteroplasia | Retinitis Pigmentosa 3 | Fetal Alcohol Syndrome | Anencephaly | Tularemia | Coffin-Siris Syndrome | Pemphigus Vulgaris | Overactive Bladder | Spinal Cord Diseases | Achromatopsia | Biotinidase Deficiency | Lymphoma, Mantle Cell | Hashimoto Thyroiditis | Thrombocythemia, Essential | Hereditary Coproporphyria | Lymphoma | Glaucomatocyclitic Crisis | Microphthalmia | Epiphyseal Chondrodysplasia, Miura Type | Genitopatellar Syndrome | Tetanus | Goiter, Nodular | Desmosterolosis | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Diffuse Mesangial Sclerosis | Cirrhosis | Guttate Psoriasis | Hyperekplexia | Angioimmunoblastic T-cell Lymphoma | Sensorineural Hearing Loss | Whipple's Disease | Holt-Oram Syndrome | Danon Disease | Gangliosidosis, GM1 | Hereditary Multiple Exostoses | Adenomatoid Tumor | Opisthorchiasis | Joubert Syndrome 2 | Cole-Carpenter Syndrome | Hereditary Hemorrhagic Telangiectasia | Chronic Beryllium Disease | Multiple Sclerosis, Chronic Progressive | Parkinsonism | Branchiootorenal Syndrome | Neonatal Progeroid Syndrome | Vascular Cognitive Impairment | Barrett Esophagus | Chronic Neutrophilic Leukemia | Conjunctivitis, Allergic | Hepatitis, Autoimmune | Microcephaly | Spondylocostal Dysostosis | Wilson's Disease | Avellino Corneal Dystrophy | Chronic Idiopathic Myelofibrosis | Pre-eclampsia | Autism | Benign Recurrent Intrahepatic Cholestasis 1 | Atrial Septal Defect | Papillorenal Syndrome | Rosacea | Epicondylitis | Cardiospondylocarpofacial Syndrome | HELLP Syndrome | Hemochromatosis | Prostatitis | Dyskeratosis Congenita | Hypogammaglobulinemia | Meningococcal Infections | Intracranial Hypertension | Carcinoma, Transitional Cell | Poirier-Bienvenu Neurodevelopmental Syndrome | Adult Polyglucosan Body Disease | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Papilledema | Hypercalciuria | Tyrosinemia Type 1 | Acrodermatitis | Pulmonary Capillary Hemangiomatosis | Enterocolitis, Necrotizing | Pyelonephritis | Behavioral Variant Of Frontotemporal Dementia | Hyperoxaluria